Focus
Quale biopsia?
V. Villanacci
Settembre 2005 - pagg. 442 -455
Abstract
When diagnosing celiac disease, the intestinal biopsy represents a moment of close collaboration
between the pathologist and the clinician. The accuracy of the hystological diagnosis
depends on the number and the adequate placement of the biopsies on the slides. It
is fundamental to correctly interpret the biopsy in order to recognise artefacts and to describe
the different mucosal strata, the relation between villus/crypt and the presence of intraepithelial
lymphocytes. All these characteristics are of great help for the clinician in order
to identify non clear celiac forms.
Parole chiave
Suggerite dall'AI
Classificazione MeSH
Bibliografia
1. Green PH, Jabri B. Coeliac disease. Lancet
2003;362:383-91.
2. Auriati L, Truini M, Sebastiani P, Bruzzone G, Fiocca R. Use of cellulose millipore filters for the correct orientation of endoscopic biopsies in digestive diseases. Pathologica 2003;95:146-51.
3. Hayat M, Cairns A, Dixon MF, O’Mahony S. Quantitation of intraepithelial lymphocytes in human duodenum: what is normal? J Clin Pathol 2002;55:393-4.
4. Ferguson A, Ziegler K. Intraepithelial lymphocyte mitosis in a jejunal biopsy correlates with intraepithelial lymphocytes count, irrespective of diagnosis. Gut 1986;27:675-9.
5. Marsh MN. Grains of truth: evolutionary changes in small intestinal mucosa in response to environmental antigen challenge. Gut 1990;31:111-4.
6. Oberhuber G, Granditsch G, Vogelsang H. The histopathology of celiac disease: time for standardized report scheme for pathologists. Eur J Gastroenterol Hepatol 1999;11:1185-94.
7. Rostami K. From microenteropathy to villous atrophy: what is treatable? Dig Liver Dis 2003;35:758-73.
8. Antonioli DA. Celiac disease: a progress report. Mod Pathol 2003;16:342-6.
9. Rostami K, Kerckhaert J, Tiemessen R, et al. Sensitivity of antiendomysium and antigliadin antibodies in untreated celiac disease: disappointing in clinical practice. Am J Gastroenterol 1999;94:888-94.
10. Kakar S, Nehera V, Murray JA, Dayharsh GA, Burgart LJ. Significance of intraepithelial lymphocytosis in small bowel biopsy samples with normal mucosal architecture. Am J Gastroenterol 2003;98:2027-33.
11. Jarvinen TT, Kaukinen K, Laurila K, et al. Intraepithelial lymphocytes in celiac disease. Am J Gastroenterol 2003;98:1332-7.
12. Patey-Mariaud de Serre N, Cellier C, Jabri B, et al. Distinction between coeliac disease and refractory sprue: a simple immunohistochemical method. Histopathology 2000;37:70-7.
2. Auriati L, Truini M, Sebastiani P, Bruzzone G, Fiocca R. Use of cellulose millipore filters for the correct orientation of endoscopic biopsies in digestive diseases. Pathologica 2003;95:146-51.
3. Hayat M, Cairns A, Dixon MF, O’Mahony S. Quantitation of intraepithelial lymphocytes in human duodenum: what is normal? J Clin Pathol 2002;55:393-4.
4. Ferguson A, Ziegler K. Intraepithelial lymphocyte mitosis in a jejunal biopsy correlates with intraepithelial lymphocytes count, irrespective of diagnosis. Gut 1986;27:675-9.
5. Marsh MN. Grains of truth: evolutionary changes in small intestinal mucosa in response to environmental antigen challenge. Gut 1990;31:111-4.
6. Oberhuber G, Granditsch G, Vogelsang H. The histopathology of celiac disease: time for standardized report scheme for pathologists. Eur J Gastroenterol Hepatol 1999;11:1185-94.
7. Rostami K. From microenteropathy to villous atrophy: what is treatable? Dig Liver Dis 2003;35:758-73.
8. Antonioli DA. Celiac disease: a progress report. Mod Pathol 2003;16:342-6.
9. Rostami K, Kerckhaert J, Tiemessen R, et al. Sensitivity of antiendomysium and antigliadin antibodies in untreated celiac disease: disappointing in clinical practice. Am J Gastroenterol 1999;94:888-94.
10. Kakar S, Nehera V, Murray JA, Dayharsh GA, Burgart LJ. Significance of intraepithelial lymphocytosis in small bowel biopsy samples with normal mucosal architecture. Am J Gastroenterol 2003;98:2027-33.
11. Jarvinen TT, Kaukinen K, Laurila K, et al. Intraepithelial lymphocytes in celiac disease. Am J Gastroenterol 2003;98:1332-7.
12. Patey-Mariaud de Serre N, Cellier C, Jabri B, et al. Distinction between coeliac disease and refractory sprue: a simple immunohistochemical method. Histopathology 2000;37:70-7.