Sette lattanti rossi: dalla dermatite atopica ai difetti congeniti dell’immunità

Seven infants with severe dermatitis, diarrhoea and/or infections are described. A primary immunodeficiency (PID) was considered among the diagnostic hypotheses in all cases. Thrombocytopenia, hypereosinophilia, lymphopenia and Ig deficiencies were adjunctive elements to consider PID in 3 cases. In 5 out of 7 cases a PID was confirmed. In the 2 remaining cases, cutaneous infection and adverse reaction to drugs were the final diagnoses. We recommend a thorough diagnostic work up for PID in “red” infants with diarrhoea and/or severe infections.