Wheezing ricorrente, sinusite, reflusso gastro-esofageo

Description of a very instructive case of chronic asthma, scarcely sensible to bronchodilators and environmental prophylaxis. An antibiotic treatment for concurrent sinusitis cured the latter, but not asthma which kept on worsening, despite of a heavy treatment, started with chromones, continued with chronically administered inhalant steroids and bronchodilators. A pathologic gastroesophageal reflux was identified. Asthma and reflux were permanently cured with a treatment based on omeprazole+cisapride to stop the asthma>GER>asthma vicious circle.