Focus
Il trapianto epatico in etŕ pediatrica: il punto attuale di un Centro italiano
LIVER TRANSPLANTATION IN CHILDREN: THE EXPERIENCE OF AN ITALIAN CENTRE
G. Torre, M. Spada, S. Riva, et al.
Maggio 2002 - pagg. 302 -310
Abstract
The Authors report their experience on liver transplantation in children at the Pediatric Liver
Transplantation Program, Ospedali Riuniti of Bergamo. Over a five year period 156 transplantations
have been performed in 141 children (15 children required retransplantation).
Most interventions have been performed by the “split in situ” technique. The main indication
(62% of all cases) was biliary tree atresia. The median age was 1,5 years. The average
waiting time to surgery was less than one month. Vascular complications occurred in 14
cases; biliary complications in 25 cases. Since tacrolimus has been used for immunosuppression,
the likelihood of acute rejection has been lowered to less than 20%. Free yearsurvival
its over 85%.
Parole chiave
Classificazione MeSH
Bibliografia
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6. Colledan M, Andorno E, Valente U, et al. A new splitting technique for liver grafts. Lancet 1999;353:1763.
7. Gridelli B, Spada M, Riva S, et al. Circulating Epstein-Barr virus DNA to monitor lymphoproliferative disease following pediatric liver transplantation. Transpl Int 2000;13 Suppl 1:S399-401.
8. Kerkar N, Hadzic N, Davies ET, et al. De-novo autoimmune hepatitis after liver transplantation. Lancet 1998;351:409-1.
2. Spada M, Gridelli B, Colledan M, et al. Extensive use of split liver for pediatric liver transplantation: a single-center experience. Liver Trans 2000;6: 415-28.
3. Kelly DA. Current results and envolving indications for liver transplantation in children. J Pediatr Gastroenterol Nutr 1998;2:214-21.
4. Chardot C, Carton M, Spire-Bendelac N, et al. Prognosis of biliary Atresia in the era of liver Transplantation. French National Study from 1986 to 1996. Hepatology 1999;30:606-11.
5. Rogiers X, Malagň M, Habib N, et al. In situ splitting of the liver in the heart-beating cadaveric organ donor for transplantation in two recipients. Transplantation 1995;59:1081-3.
6. Colledan M, Andorno E, Valente U, et al. A new splitting technique for liver grafts. Lancet 1999;353:1763.
7. Gridelli B, Spada M, Riva S, et al. Circulating Epstein-Barr virus DNA to monitor lymphoproliferative disease following pediatric liver transplantation. Transpl Int 2000;13 Suppl 1:S399-401.
8. Kerkar N, Hadzic N, Davies ET, et al. De-novo autoimmune hepatitis after liver transplantation. Lancet 1998;351:409-1.