Focus
Il test rapido nell’esperienza di chi l’ha inventato
THE RAPID TEST FOR COELIAC DISEASE IN THE EXPERIENCE OF ITS INVENTORS
M. Mäki, I. Korponay-Szabó
Giugno 2008 - pagg. 361 -370
Abstract
Coeliac disease is an autoimmune enteropathy triggered by the ingestion of gluten in genetically
susceptible individuals. The diagnosis is suspected upon the presence of typical
autoantibodies in the serum of patients, and confirmed by intestinal biopsy. For a long time,
these serologic tests were only performable in laboratories. The availability of a rapid
test, that can be performed on a large scale, in any setting has significantly simplified the
diagnosis of coeliac disease. The Authors of the article explain the way the test functions,
the clinical implications and the literature that proved the test as an effective addition to the
previously available diagnostic tools for the diagnosis of coeliac disease.
Parole chiave
Classificazione MeSH
Bibliografia
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2. Raivio T, Kaukinen K, Nemes E, et al. Self transglutaminase-based rapid coeliac disease antibody detection by a lateral flow method. Aliment Pharmacol Ther 2006;24:147-54.
3. Raivio T, Korponay-Szabó IR, Collin P, et al. Performance of a new rapid whole blood celiac test in adult patients with low prevalence of endomysial antibodies. Dig Liv Dis 2007;39: 1057-63.
4. Korponay-Szabó IR, Szabados K, Pusztai J, et al. Population screening for coeliac disease in primary care by district nurses using a rapid antibody test: diagnostic accuracy and feasibility study. BMJ 2007;335:1244-7.
5. von Lode P. Point-of-care immunotesting: approaching the analytical performance of central laboratory methods. Clin Biochem 2005;38:591-606.
2. Raivio T, Kaukinen K, Nemes E, et al. Self transglutaminase-based rapid coeliac disease antibody detection by a lateral flow method. Aliment Pharmacol Ther 2006;24:147-54.
3. Raivio T, Korponay-Szabó IR, Collin P, et al. Performance of a new rapid whole blood celiac test in adult patients with low prevalence of endomysial antibodies. Dig Liv Dis 2007;39: 1057-63.
4. Korponay-Szabó IR, Szabados K, Pusztai J, et al. Population screening for coeliac disease in primary care by district nurses using a rapid antibody test: diagnostic accuracy and feasibility study. BMJ 2007;335:1244-7.
5. von Lode P. Point-of-care immunotesting: approaching the analytical performance of central laboratory methods. Clin Biochem 2005;38:591-606.