Rivista di formazione e aggiornamento professionale del pediatra e del medico di base, fondata nel 1982. In collaborazione con l'Associazione Culturale Pediatri.
Login Abbonamenti Pubblicazioni Carrello Registrazione Perché registrarsi? Contatti

Focus

PDF

Cercare la celiachia con il test rapido: l’esperienza indiana

SEARCHING FOR COELIAC DISEASE USING THE RAPID TEST: THE INDIAN EXPERIENCE

A. Phillips, M. Mäki, T. Not, S. Bhatnagar

Giugno 2008 - pagg. 361 -370

Abstract
Coeliac disease was first reported in India in the 1960s. Over the last decade, coeliac disease has been increasingly recognized and is considered to have a significant presence in the country. The Authors report from an on-going study where in a series of 231 children with chronic diarrhoea, abdominal distension, and growth failure the rapid test (Biocard POC) was performed. The results were compared to anti-endomisium (EMA) antibodies and duodenal biopsy. The preliminary analysis of the study so far shows that the Biocard POC test has good specificity but it has a high false negative rate. However, it does appear that POC-testing is a useful adjunct to formal diagnostic testing, although it must be used in a setting that has access to specialized facilities where the diagnosis can be confirmed
Parole chiave
Suggerite dall'AI

Bibliografia

1. Walia BN, Sidhu JK, Tandon BN, Ghai OP, Bhargava S. Celiac disease in North Indian children. Br Med J 1966;2:1233-4.
2. Walia BN, Mehta S, Gupte SP. Coeliac disease. Indian Pediatr 1972;9:16-9.
3. Romijn JA, Mulder CJ, Erwteman TW, Sauerwein HP, Tytgat GN. Summer disease in Punjab (coeliac disease). J Indian Med Assoc 1987;85:54-6.
4. Khoshoo V, Bhan MK, Jain R, et al. Coeliac disease as cause of protracted diarrhoea in Indian children. Lancet 1988;1:126-7.
5. Khoshoo V, Bhan MK, Unsworth DJ, Kumar R, Walker Smith JA. Anti-reticulin antibodies: useful adjunct to histopathology in diagnosing coeliac disease, especially in a developing country. J Pediatr Gastroenterol Nutr 1988;7:864-6.
6. Khoshoo V, Bhan MK. Coeliac disease in Indian children. Indian Pediatr 1989;26:627-9.
7. Khoshoo V, Bhan MK, Puri S, et al. Serum anti-gliadin antibody profile in childhood protracted diarrhoea due to coeliac disease and other causes in a developing country. Scand J Gastroenterol 1989;24:1212-6.
8. Nelson R, McNeish AS, Anderson CM. Coeliac disease in children of Asian immigrants. Lancet 1973;1:348-50.
9. Sher KS, Fraser RC, Wicks AC, Mayberry JF. High risk of coeliac disease in Punjabis. Epidemiological study in the south Asian and European populations of Leicestershire. Digestion 1993;54:178-82.
10. Bhatnagar S, Bhan MK. Serological diagnosis of coeliac disease. Indian J Pediatr 1999;66(1 Suppl):S26-31.
11. Poddar U, Thapa BR, Nain CK, Prasad A, Singh K. Coeliac disease in India: are they true cases of celiac disease? J Pediatr Gastroenterol Nutr 2002;35:508-12.
12. Bhatnagar S, Natchu MU. Coeliac disease in Indian children. Natl Med J India 2004;17: 124-7.
13. Bhatnagar S, Gupta SD, Mathur M, et al. Coeliac disease with mild to moderate histologic changes is a common cause of chronic diarrhea in Indian children. J Pediatr Gastroenterol Nutr 2005;41:204-9.
14. Mohindra S, Yachha SK, Srivastava A, et al. Coeliac disease in Indian children: assessment of clinical, nutritional and pathologic characteristics. J Health Popul Nutr 2001;19: 204-8.
15. Sood A, Midha V, Sood N, Kaushal V, Puri H. Increasing incidence of coeliac disease in India. Am J Gastroenterol 2001;96:2804-5.
16. Ventura A, Magazzù G, Greco L. Duration of exposure to gluten and risk for autoimmune disorders in patients with coeliac disease. SIGEP Study Group for Autoimmune Disorders in Coeliac Disease. Gastroenterol 1999; 117:297-303.
17. Logan RF, Rifkind EA, Turner ID, Ferguson A. Mortality in coeliac disease. Gastroenterol 1989;97:26571.
18. Corrao G, Corazza GR, Bagnardi V, et al. Club del Tenue Study Group. Mortality in patients with coeliac disease and their relatives: a cohort study. Lancet 2001;358:356-61.
19. Holmes GK, Prior P, Lane MR, Pope D, Allan RN. Malignancy in coeliac disease: effect of a gluten free diet. Gut 1989;30:333-8.