Pagine elettroniche ; Ricerca
Valore diagnostico del test rapido
anti-transglutaminasi tissutale:
l'esperienza slovena
DIAGNOSTIC ACCURACY OF THE RAPID ANTI-TISSUE TRANSGLUTAMINASE TEST: The Slovenian experience
J. Dolinšek, D. Urlep, D. Mičetić-Turk.
Giugno 2008 - pagg. 395 -397
Abstract
The rapid test for coeliac disease (CD) has been
used in the north-east region of Slovenia in the past two
years. The Authors report an experience involving 200
subjects that were either suspected to have CD or known to
be coeliacs. They evaluated the sensitivity and specificity of
the test by comparing the results of the rapid test to EMA antibodies.
Overall, 33 new celiacs have been identified, they
followed 32 CD patients that came to follow up and 135 controls.
The estimated sensibility of the study in diagnosing CD
was 79%, the specificity 97%. The specificity increased to
91% if the result was read after 10 minutes, instead of the 5
minutes indicated by the producer. The Authors suggest that
the rapid test is accurate in identifying new CD patients, but
has limited usefulness in evaluating the compliance of the patient
to the diet. In some cases the test should be read after
10 minutes to correctly evaluate the result.
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Corrispondenza: jernej_dolinsek@hotmail.com
