Focus
La tonsillite ricorrente e la tonsillite focale: una rivisitazione
FOCAL AND RECURRENT PHARYNGITIS: A REVIEW
P. D’Agaro, F. Panizon, A. Ventura, E. Zocconi
Aprile 2001 - pagg. 231 -238
Abstract
20 cases of recurrent pharyngitis, among whom 9 have undergone tonsillectomy, are compared
with 9 cases of tonsillar hypertrophy, all of whom had undergone surgery. Adenovirus
etiology was confirmed in 8 out of 14 cases belonging to the first group in whom appropriate
laboratory examinations could be performed, and in 1 out of 9 cases of the second
group. Based on these findings and on a literature review an auto-inflammatory hypothesis
of recurrent pharyngitis is proposed. Adenovirus, and EBV in older children could
be the sensitising agent. The Authors suggest that recurrent pharyngitis, when criteria of cyclicity,
abnormality of inflammatory markers and intercritical normality are satisfied, may
not be differentiated from FPAPA syndrome.
Parole chiave
Classificazione MeSH
Bibliografia
1. Sprinkles PM, Veltri RW. Recurrent adenotonsillitis:
a new concept. Laryngoscope
1975:58.
2. Lekston-Himes JA, Dale JK, Kingma DW, et al. Periodic illness associated with Epstein- Barr virus infection. Clin Infect Dis 1996;81: 141.
3. Ramirez A, Peidrola D, Lopez A, et al. Beta- hemolytic streptococci in tonsyl hypertrophy and recurrent tonsillitis. Enferm Infec Microbiol Clin 1997;15:315.
4. Oesterlund A, Popa R, Nikkilae T, et al. Intracellular reservoir of Streptococcus pyogenes in vivo: a possible explanation for recurrent pharyngotonsillitis. Laryngoscope 1997;107: 640.
5. De Miguel Martinez I, Ramos Macias A, Munoz Bellido JL, del Canizo Alvarez A. Therapeutic possibilities in recurrent infantile tonsillitis. Acta Otorhinolaryngol Esp 1994; 45:433
6. Gaffney RJ, Cafferkey MT. Bacteriology of normal and diseased tonsils assessed by fineneedle aspiration: Haemophilus influenzae and the pathogenesis of recurrent acute tonsillitis. Clin Otorhinolaryngol 1998;23:181.
7. Huminer D, Levy R, Pitlik S, Samra Z. Mycoplasma and Chlamydia in adenoids and tonsils of children undergoing adenoidectomy or tonsillectomy. Arch Otol Rhinol Laryngol 1994;103:135.
8. Yamanaka N, Kataura A. Viral infections associated with recurrent tonsillitis. Acta Otolarhyngol 1984;416:30
9. Mendoza A, Panizon F. La tonsillite ricorrente da Adenovirus. Medico e Bambino 1998;17:378.
10. Maeda S, Mogi G. Functional Morphology of tonsillar crypts in recurrent tonsillitis. Acta Otolaryngol 1984;(suppl)416:7.
11. Mitani T, Tomoda K, Maeda S, et al. The tonsillar immune system: its response to exogenous antigens. Acta Otolaryngol 1990; 475:1.
12. Yamanaka N, Yokoyama M, Kawaguchi T, et al. Role of gamma/delta cells in palatine tonsil. Acta Otolaryngol 1996;(suppl)523:90.
13. Kuki K, Tabata T. Immunoistological studies on tonsils with recurrent tonsillitis and focus-tonsil with pustulosis palmaris et plantaris. Acta Otolaryngol 1984;416:20.
14. Bussi M, Carlevato MT, Panizzut B, et al. Expression of antigens associated with the individual stages of the inflammatory response in child and adult as a possibile distinctive method for recurrent and chronic tonsillitis. Intern J Otorhinolaryngol 1996;35:243.
15. Bussi M, Carlevato MT, Panizzut B, et al. Are recurrent and chronic tonsillitis different entities? An immunological study with specific markers of inflammatory stages. Acta Otolaryngol 1996;523:112.
16. Padeh S, Brezniak N, Zemer D, et al. Periodic fever, aphtous stomatitis, pharyngitis, and adenopathy syndrome: clinical characteristics and outcome. J Pediatr 1999;135:98.
17. Marshall GS, Edwards KM, Butler J, Lawton AR. Syndromes of periodic fever, pharyngitidis and aphtous stomatitis. Pediatr Infect Dis J 1987;110:43.
18. Thomas KT, Feder HM jr, Lawton AR, Edwards KM. Periodic fever syndrome in children. J Pediatr 1999;135:15.
2. Lekston-Himes JA, Dale JK, Kingma DW, et al. Periodic illness associated with Epstein- Barr virus infection. Clin Infect Dis 1996;81: 141.
3. Ramirez A, Peidrola D, Lopez A, et al. Beta- hemolytic streptococci in tonsyl hypertrophy and recurrent tonsillitis. Enferm Infec Microbiol Clin 1997;15:315.
4. Oesterlund A, Popa R, Nikkilae T, et al. Intracellular reservoir of Streptococcus pyogenes in vivo: a possible explanation for recurrent pharyngotonsillitis. Laryngoscope 1997;107: 640.
5. De Miguel Martinez I, Ramos Macias A, Munoz Bellido JL, del Canizo Alvarez A. Therapeutic possibilities in recurrent infantile tonsillitis. Acta Otorhinolaryngol Esp 1994; 45:433
6. Gaffney RJ, Cafferkey MT. Bacteriology of normal and diseased tonsils assessed by fineneedle aspiration: Haemophilus influenzae and the pathogenesis of recurrent acute tonsillitis. Clin Otorhinolaryngol 1998;23:181.
7. Huminer D, Levy R, Pitlik S, Samra Z. Mycoplasma and Chlamydia in adenoids and tonsils of children undergoing adenoidectomy or tonsillectomy. Arch Otol Rhinol Laryngol 1994;103:135.
8. Yamanaka N, Kataura A. Viral infections associated with recurrent tonsillitis. Acta Otolarhyngol 1984;416:30
9. Mendoza A, Panizon F. La tonsillite ricorrente da Adenovirus. Medico e Bambino 1998;17:378.
10. Maeda S, Mogi G. Functional Morphology of tonsillar crypts in recurrent tonsillitis. Acta Otolaryngol 1984;(suppl)416:7.
11. Mitani T, Tomoda K, Maeda S, et al. The tonsillar immune system: its response to exogenous antigens. Acta Otolaryngol 1990; 475:1.
12. Yamanaka N, Yokoyama M, Kawaguchi T, et al. Role of gamma/delta cells in palatine tonsil. Acta Otolaryngol 1996;(suppl)523:90.
13. Kuki K, Tabata T. Immunoistological studies on tonsils with recurrent tonsillitis and focus-tonsil with pustulosis palmaris et plantaris. Acta Otolaryngol 1984;416:20.
14. Bussi M, Carlevato MT, Panizzut B, et al. Expression of antigens associated with the individual stages of the inflammatory response in child and adult as a possibile distinctive method for recurrent and chronic tonsillitis. Intern J Otorhinolaryngol 1996;35:243.
15. Bussi M, Carlevato MT, Panizzut B, et al. Are recurrent and chronic tonsillitis different entities? An immunological study with specific markers of inflammatory stages. Acta Otolaryngol 1996;523:112.
16. Padeh S, Brezniak N, Zemer D, et al. Periodic fever, aphtous stomatitis, pharyngitis, and adenopathy syndrome: clinical characteristics and outcome. J Pediatr 1999;135:98.
17. Marshall GS, Edwards KM, Butler J, Lawton AR. Syndromes of periodic fever, pharyngitidis and aphtous stomatitis. Pediatr Infect Dis J 1987;110:43.
18. Thomas KT, Feder HM jr, Lawton AR, Edwards KM. Periodic fever syndrome in children. J Pediatr 1999;135:15.