Rivista di formazione e aggiornamento professionale del pediatra e del medico di base, fondata nel 1982. In collaborazione con l'Associazione Culturale Pediatri.
Login Abbonamenti Pubblicazioni Carrello Registrazione Perché registrarsi? Contatti

Ricerca

PDF

La sindrome mononucleosica: revisione di 107 casi

Infectious mononucleosis: a review of 107 cases

C. Geraci, M. Pocecco

Ottobre 2012 - pagg. 521 -523

Abstract
Childhood infectious mononucleosis is a benign and self-limited disease. Complications are rare but not unremarkable: 3 out of 107 patients experienced haematological complications (1 autoimmune haemolytic anaemia and 2 autoimmune thrombocytopenia), 2 of which required specific treatment (blood transfusion and IvIg respectively). Steroid treatment was reserved to patients with respiratory obstruction or prolonged fever with poor general condition and symptomatic effect was observed in all of the treated cases within 24 hours. The risk/benefit ratio of steroid treatment was justified by the brief period of therapy (4 days) and the dose (1 mg/kg of prednisone or 0.1 mg/kg of betamethasone).

Bibliografia

1. Kliegman R, Stanton B, St. Geme J, et al. Nelson Textbook of Pediatrics, 19th Edition 2011. 2. Tanaka M, Kamijo T, Koike K, et al. Specific autoantibodies to platelet glycoproteins in Epstein-Barr virus-associated immune thrombocytopenia. Int J Hematol 2003;78:168- 70. 3. Candy B, Hotopf M. Steroids for symptom control in infectious mononucleosis. Cochrane Database Syst Rev 2006;(3):CD004402. 4. Luzuriaga K, Sullivan JL. Infectious mononucleosis. N Engl J Med 2010;362:1993-2000. 5. Collins M, Fleisher G, Kreisberg J, Fager S. Role of steroids in the treatment of infectious mononucleosis in the ambulatory college student. J Am Coll Health 1984;33:101-5. 6. Thompson SK, Doerr TD, Hengerer AS. Infectious mononucleosis and cor ticosteroids: management practices and outcomes. Arch Otolaryngol Head Neck Surg 2005;131: 900-4.

Corrispondenza: mpocecco@ausl-cesena.emr.it