Problemi speciali
La comorbiditŕ cefalea-epilessia nel bambino: revisione critica dei dati della letteratura
Headache and epilepsy comorbidity in children: a critical review of the literature
S. Barca, V. Belcastro, P. Striano, P. Parisi
Maggio 2014 - pagg. 304 -308
Abstract
Headache and epilepsy are both chronic neurologic disorders with episodic manifestations
and typical symptoms that enable to distinguish between them in most of the cases. Rarely,
migraine with headache and/or tension-type headache may be the sole symptom of an epileptic
seizure. The comorbidity epilepsy/headache is very frequent in children affected by
epilepsy with centrotemporal spikes (BECTS), juvenile myoclonic epilepsy (JME) and idiopathic
occipital lobe epilepsies. The overall prevalence of headache in children with epilepsy
ranges from 8% to 15%, showing even higher values on the EEG, namely 63% in children
presenting with centrotemporal spikes and 33% in children with absences. The term
ictal epileptic headache has been recently introduced to describe the very rare clinical condition
in which migraine/headache is the only symptom of an epileptic seizure. Although
the comorbidity epilepsy/headache is frequent, epileptic migraine is very rare. Therefore,
it is important to suspect, recognize and diagnose such a clinical case to avoid making
wrong diagnosis and prescribing too many radiological tests. The correct diagnostic criteria
suggested for ictal epileptic headache can help the clinician diagnose epileptic headache
in children.
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Bibliografia
1. Panayiotopoulos CP. Visual phenomena and
headache in occipital epilepsy: a review, a systematic
study and differentiation from migraine.
Epileptic Disord 1999;1:205-16.
2. Panayiotopoulos CP. “Migralepsy” and the
significance of differentiating occipital seizures
from migraine. Epilepsia 2006;47:806-8.
3. Haut SR, Bigal ME, Lipton RB. Chronic disorders
with episodic manifestations: focus on
epilepsy and migraine. Lancet Neurol 2006;
5:148-57.
4. D’Alessandro R, Sacquegna T, Pazzaglia P,
et al. Headache after partial complex seizures.
In: Andermann FA, Lugaresi E (Eds). Migraine
and epilepsy. Boston: Butterworth Publishers,
1987:273-8.
5. Belcastro V, Striano P, Parisi P. From migralepsy
to ictal epileptic headache: the story
so far. Neurol Sci 2013;34(10):1805-7.
6. Sances G, Guaschino E, Perucca P, Allena
M, Ghiotto N, Manni R. Migralepsy a call for a
revision of the definition. Epilepsia 2009;50:
2487-96.
7. Kelley SA, Hartman AL, Kossoff EH. Comorbidity
of migraine in children presenting
with epilepsy to a tertiary care center. Neurology
2012;79(5):468-73.
8. Sacco S, Olivieri L, Bastianello S, Carolei A.
Comorbid neuropathologies in migraine. J
Headache Pain 2006;7:222-30.
9. Lipton RB, Silberstein SD. Why study the
comorbidity of migraine? Neurology 1994;44
(S1):S4-5.
10. De Romanis F, Buzzi MG, Cerbo R, Feliciani
M, Assenza S. Agnoli A. Migraine and
epilepsy with infantile onset and electroencephalographic
findings of occipital spikewave
complexes. Headache 1991;31:378-83.
11. De Simone R, Ranieri A, Marano E, et al.
Migraine and epilepsy: clinical and pathophysiological
relations. Neurol Sci 2007;28:
150-5.
12. Andermann E, Andermann F. Migraineepilepsy
relationships: epidemiological and
genetic aspects. In: Andermann F, Lugaresi E
(Eds). Migraine and epilepsy. Boston: Butterworth
Publishers, 1987:281-91.
13. Piccinelli P, Borgatti R, Nicoli F, et al. Relationship
between migraine and epilepsy in pediatric
age. Headache 2006;46:413-21.
14. Ludvigsson P, Hesdorffer D, Olafsson E,
Kjartansson O, Hauser WA. Migraine with aura
is a risk factor for unprovoked seizures in
children. Ann Neurol 2006;59(1):210-3.
15. Leniger T, von den Driesch S, Isbruch K,
Diener HC, Hufnagel A. Clinical characteristics
of patients with comorbidity of migraine
and epilepsy. Headache 2003;43:672-7.
16. Toldo I, Perissinotto E, Menegazzo F, et al.
Comorbidity between headache and epilepsy
in a pediatric headache center. J Headache
Pain 2010;11(3):235-40.
17. Headache Classification Subcommittee of
the International Headache Society. The International
Classification of Headache Disorders:
2nd edition. Cephalalgia 2004;24(Suppl.
1):9-160.
18. Headache Classification Committee of the
International Headache Society (IHS). The International
Classification of Headache Disorders,
3rd edition (beta version). Cephalalgia
2013;33(9):629-808.
19. Berg AT, Berkovic SF, Brodie MJ, et al. Revised
terminology and concepts for organization
of seizures and epilepsies: report of the
ILAE Commission on Classification and Terminology,
2005-2009. Epilepsia 2010;51:676-
85.
20. Parisi P. Why is migraine rarely, and not
usually, the sole ictal epileptic manifestation?
Seizure 2009;18:309-12.
21. Lennox WG, Lennox MA. Epilepsy and related
disorders. Boston: Little-Brown, 1960.
22. Verrotti A, Coppola G, Di Fonzo A, et al.
Should “migralepsy” be considered an obsolete
concept? A multicenter retrospective clinical/
EEG study and review of the literature.
Epilepsy Behav 2011a;21:52-9.
23. Verrotti A, Striano P, Belcastro V, et al. Migralepsy
and related conditions: advances in
pathophysiology and classification. Seizure
2011b;20:271-5.
24. Belcastro V, Striano P, Parisi P. Is it migralepsy?
No evidence yet. Neurol Sci 2013;
34(10):1837-8.
25. Belcastro V, Striano P, Kasteleijn D, Villa MP,
Parisi P. Migralepsy, hemicrania epileptica, postictal
headache and “ictal epileptic headache”: a
proposal for terminology and classifications revision.
J Headache Pain 2011a;12:289-94.
26. Cianchetti C, Pruna D, Ledda M. Epileptic
seizures and headache-migraine: A review on
types of association and terminology. Seizure
2013;22(9):679-85.
27. Parisi P, Striano P, Verrotti A, Villa MP, Belcastro
V. What have we learned about ictal
epileptic headache? A review of well-documented
cases. Seizure 2013;22(4):253-8.
28. Andermann F, Zifkin B. The benign occipital
epilepsies of childhood: an overview of the
idiopathic syndromes and of the relationship
to migraine. Epilepsia 1998;39:9-23.
29. Parisi P, Striano P, Negro A, Martelletti P,
Belcastro V. Ictal epileptic headache: an old
story with courses and appeals. J Headache
Pain 2012a;13(8):607-13.
30. Belcastro V, Striano P, Parisi P. Interictal
and periictal headache in patients with epilepsy:
migraine-triggered seizures or epilepsytriggered
headache? Eur J Neurol 2013;20
(10):1333-4.
31. Belcastro V, Striano P, Pierguidi L, Calabresi
P, Tambasco N. Ictal Epileptic Headache
Mimicking Status Migrainosus: EEG and
DWI-MRI Findings. Headache 2011b;51:160-2.
32. Parisi P, Striano P, Trenité DG, et al. “Ictal
epileptic headache”: recent concepts for new
classifications criteria. Cephalalgia 2012b;32
(9):723-4.
Corrispondenza: vincenzobelcastro@libero.it
