Focus
Una febbre alta e persistente con epatosplenomegalia e citopenia
High and persistent fever with epatosplenomegaly and cytopenia
L. de Seta, M.S. Sabatino, F. de Seta, P. Siani
Settembre 2015 - pagg. 431 -441
Abstract
The case described is that of an 11-year-old child presenting with high fever, pharyngotonsillar
exudate, submandibular strangles and hepatosplenomegaly. The elevated number
of VCA IgM antibodies led to a diagnosis of infectious mononucleosis. The persistence
of the fever for more than two weeks associated with thrombocytopenia and anaemia
and the serious general conditions of the patient have induced the provider to
perform a fine-needle bone marrow aspiration that has revealed the presence of macrophages
in active hemophagocytosis. This condition, associated with other symptoms,
has resulted in the diagnosis of a secondary hemophagocytic lymphohistiocytosis, a rare
and serious complication of infectious mononucleosis.
Classificazione MeSH
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Corrispondenza: ludeseta@tin.it