Problemi correnti
Celiachia: dove si nasconde?
SEARCHING FOR COELIAC DISEASE: SIGNS, SYMPTOMS, COMPLICATIONS, ASSOCIATED DISEASE
LUIGI GRECO, SIMONA ERRICHIELLO
Dipartimento di Pediatria, Università degli Studi di Napoli “Federico II”
Settembre 2001 - pagg. 437 -447
Abstract
The article offers an overview, based on 329 bibliographic references, of coeliac disease.
Typical as well as atypical presenting signs and symptoms are described. The main clinical
features, the complications and the associated syndromes and diseases are listed, including
all clinical conditions where investigating for possible coeliac disease as a possible underlying
cause is recommended.
Parole chiave
Suggerite dall'AI
Classificazione MeSH
Bibliografia
sensitive
enteropathy. Pediatric Gastroenterology,
1996;43:335-73.
2. Ventura A, Magazzù G, Greco L. Duration of Exposure to gluten and risk of autoimmune disorders in patients with coeliac disease. Gastroenterology 1999;11:297-303.
3. Egan CA, O’Loughlin S, Gormally S, et al. Dermatitis herpetiform: a review of fifty-four patients. Ir J Med Sci 1997 Oct- Dec,1666(4):241-4.
4. Reunala T. Dermatitis herpetiform: coelic disease of the skin. Ann Med 1998;30(5):416-8.
5. Loche F, Bazex J. Celiac disease association with cutaneous sarcoidosic granuloma. Med Interne 1997;18(12):975-8.
6. Tasanen K, Raudasoja R, Kallioinemn M, et al. Erythema elevatum diutinum in association with coeliac disease. Br J Dermatol 1997 April,1366(4):624-7.
7. Rodriguez-Serna M, Fortea JM, Perez A, et al. Erythema elevatum diutinum associated with celiac disease: response to a gluten-free diet. Pediatr Dermatol 1993 June;10(2):125-8.
8. Garcia-Patos V, Pujol RM, Barnadas MA, et al. Generalized acquired cutis laxa associated with coeliac disease: evidence of immunoglobulin A deposits on the dermal elastic fibres. Br Dermatol 1996 Jul;135(1):130-4.
9. Thorisdottir K, Camisa C, Tomecki KJ, et al. Necrolytic migratory erythema: a report of three cases. J Am Acad Dermatol 1994 Feb;30(2 Pt 2):324-9.
10. Collin P, Pukkala E, Reunala T. Malignancy and survival in dermatitis herpetiformis: a comparison with coeliac disease. Gut 1996 Apr; 38(4):528-30.
11. Marzano AV, Capsoni F, Berti, et al. Amicrobial pustular dermatosis of cutaneous folds associated with autoimmune disorders: a new entity? Dermatology 1996;193(2):88-93.
12. Kapur A, Isaacs PE, Kelsey PR. Linear IgA dermatosis, coeliac disease, and extraintestinal B cell lymphoma. Gut 1995 Nov;37(5):731-3.
13. Cottafava F, Cosso D. Psoriatic arthritis and celiac in childhood. A case report. Pediatr Med Chir 1991 Jul-Aug;13(4):431-3.
14. Volta U, Bardazzi F, Zauli D, et al. Serological screening for coeliac disease in vitiligo and alopecia areata.Br J Dermatol 1997 May; 136(5):801-2.
15. Barbato M, Viola F, Grillo R, et al. Alopecia and coeliac disease: report of two patients shoowing response to gluten-free diet. Clin Exp Dermatol 1998 Sept;23(5):236-7.
16. Naveh Y, Rosenthal E, Ben-Arieh Y, et al. Celiac disease-associated alopecia in childhood. J Pediatr 1999 Mar;(34483):362-4.
17. Corazza GR, Andreani ML, Venturo N, et al. Coeliac disease and alopecia areata: report of a new association. Gastroenterology 1995 Oct; 109(4):133-7.
18. Michaelsson G, Gerden B. How common is gluten intolerance among patients with psoriasis? Acta Derm Venereol 1991;71(1):90
19. Valdimarsson T, Arnqvist HJ, Toss G, et al. Low circulating insulin-like growth factor-I in coeliac disease and its relation to bone mineral density. Scand J Gastrenterol 1999 Sept; 34(9):904-8.
20. Mora S, Barera G, Beccio S, et al. Bone density and bone metabolism are normal after long-term gluten-free diet in young celiac patient. Am J Gastroenterol 1999 Feb;94(2):398- 403.
21. Kemppainen T; Kroger H, Janatuinen E, et al. Bone recovery after a gluten-free diet: a 5- year follow-up study. Bone 1999 Sept;25(3):355- 60.
22. Kemppainen T, Kroger H, Janatuinen E, et al. Osteoporosis in adult patients with celiac disease. Bone 1999 Mar;24(3):249-55.
23. Meloni GF, Dessole S, Vargiu N, et al. The prevalence of coeliac disease in infertility. Hum Reprod 1999 Nov;14(11):2759-61.
24. Kolho KL, Tiitinen A, Tulppala M, et al. Screening for coeliac disease in women with a history of recurrent miscarriage or infertility. Br J Obstet Gynaecol 1999 Feb;106(2):171-3.
25. Sher KS. Jayanthi V, Probert CS, et al. Infertility, obstetric and gynaecological problems in coeliac sprue. Dig Dis 1994 May- Jun;12(3):186-90.
26. Slot O, Locht H. Arthritis as presenting symptom in silent adult coeliac disease. Two cases and review of the literature. Scand J Rheumatol 2000;29 (4):260-3.
27. Collin P, Vilska S, Heinonen PK, et al: Infertility and coeliac disease. Gut 1996 Sept;39(3): 382-4.
28. Norgard B, Fonager K, Soreensen HT, et al. Birth outcomes of women with celiac disease: a nationwide historical cohort study. Am J Gastroenterol 1999 Sept;94(9):2435-40.
29. Molteni N, Bardella MT, Bianchi PA. Obstetric and gynecological problems in women with untreated celiac sprue. J Clin Gastroenterol 1990 Feb;12(1):37-9.
30. Smecuol E, Maurino E, Vazquez H, et al. Gynaecological and obstetric disorders in coeliac disease: frequent clinical onset during pregnancy or the puerperium. Eur J Gastroenterol Hepatol 1996 Jan;8(1):63-89.
31. Sher KS, Mayberry JF. Female fertility, obstetric and gynaecological history in coeliac disease: a case control study. Acta Paediatr (Suppl) 1996 May;412:76-7.
32. Dondorp AM, de Groot GH. Onset of coeliac disease after a spontaneous miscarriage during a holiday in Australia: coincidance or casual relationship? Neth J Med 1998 Apr;52(4):147-9.
33. Ciacci C, Cirillo M, Auriemma G, et al. Celiac disease and pregnancy outcome. Am J Gastroenterol 1996 Apr;91(4):718-22.
34. Luostarinen L, Pirttila T, Collin P. Coeliac Disease Presenting with Neurological Disorders. Eur Neurol 1999 Oct;42(3):132-5.
35. Hin H, Bird G, Fisher P, et al. Coeliac disease in primary care: case finding study. BMJ 1999;318:164-7.
36. Jokinen J, Peters U, Maki M, et al. Celiac sprue in patients with chronic oral mucosal symptoms. J Clin Gastroenterol 1998 Jan;26 (1):23-6.
37. Curione M, Barbato M, De Biase L, et al. Prevalence of coeliac disease in idiopatic dilated cardiomyopathy. Lancet 1999 Jul 17;354(9174): 222-3.
38. Kull K, Uibo O, Salupere R, et al. High frequency of antigliadin antibodies and absence of antireticulum and antiendomysium antibodies in patients with ulcerative colitis. J Gastroenterol 1999 Feb:34(1):61-5.
39. Ciacci C, Derosa A, de Michele G, et al. Sexual behaviour in untreated and treated celiac patients. Eur J Gastroenterol Hepatol 1998 Aug; 10(8):649-51.
40. Lahteenoja H, Toivanen A, Viander M, et al. Oral mucosal changes in coeliac patients on gluten-free diet. Eur J Oral Sci 1998 Oct;106(5):899-906.
41. Sorensen HT, Thuulstrup AM, Blomqvist P, et al. Risk of primary biliary liver cirrhosis in patients with coeliac disease: Danish and Swedish cohort data. Gut 1999 May;44(5):736-8.
42. Cameron EA, Stewart JA, West KP, et al. Coeliac disease presenting with intra peritoneal haemorrhage. Eur J Gastroenterol Hepatol 1998 Jul:10(7):619-20.
43. Jevon GP, Dimmick JE, Dohil R, et al. Spectrum of gastritis in celiac disease in childhood. Pediatr Dev Pathol 1999 May-Jun;2(3):221-6.
44. Delco F, El-Serag HB, Sonnenberg A. Celiac sprue among US military veterans: associated disorders and clinical manifestation. Dig Dis Sci 1999 May;44(5):966-72.
45. Bhattacharyya A, Patel Mk, Tymms DJ. Coeliac disease in adult: variations on a theme. J R Soc Med 1999 Jun:92(6):286-9.
46. Prussner HT. Detecting celiac disease in your patients. Am Fam Physician 1998 Mar 1;57(5):1023-34,1039-41.
47. Dickey W, McConnel JB. How many hospital visits does it take before celiac sprue is diagnosed? J Clin Gastroenterol 1996 Jul;23(1):21- 3.
48. Varkonyi A, Boda M, Endreffy E, et al. Coeliac disease: always something to discover. Scand J Gastroenterol Suppl 1998;228:122-9.
49. Lubrano E, Ciacci C, Ames PR, et al. The arthritis of coeliac disease: prevalence and pattern in 200 adult patients. Br J Rheumatol 1996 Dec;35(12):1314-8.
50. George EK, Hertzberger-ten Cate, van Suijlekom- Smit LW, et al. Juvenile chronic arthritis and coeliac disease in The Netherlands. Clin Exp Rheumatol 1996 Sep-Oct;14(5):571-5.
51. Paimela L, Kurki P, Leirisalo-Repo M, et al. Gliadin immune reactivity in patients with rheumatoid arthritis. Clin Exp Rheumatol 1995 Sep-Oct;13(5):603-7.
52. Usai P, Boi MF, Piga M, et al. Adult celiac disease is frequently associated with sacroilitis. Dig Dis Sci 1995 Sept;40(9):1906-8.
53. Lepore L, Martelossi S, Pennesi M, et al. Prevalence of celiac disease in patients with juvenile chronic arthritis. J Pediatr 1996 Aug; 129(2):311-3.
54. Falcini F, Ferrari R, Simonini G, et al. Recurrent monoarthritis in an 11-year-old boy with occult coeliac disease. Successful and stable remission after gluten-free diet. Clin Exp Rheumatol 1999 Jul-Aug;17(4):509-11.
55. Carroccio A, Iannitto E, Cavataio F; et al. Sideropenic anemia and celiac disease: one study, two points of view. Dig Dis Sci 1998 Mar; 43(3):673-8.
56. Mahadeva R, Flower C, Shneerson J. Bronchiectasis in association with coelic disease. Thorax 1998 Jun;53(6):527-9.
57. Laudage G, Schirp J. Life threatening epistaxis due to plasma coagulation disorder as a partial manifestation of gluten sensitive enteropathy. Leber Magen Darm 1995 Mar; 25(2):94- 6.
58. Corazza GR, Valentini RA, Andreani ML, et al. Subclinical coeliac disease is a frequent cause of iron-deficiency anaemia. Scand J Gastroenterol 1995 Feb;30(2):153-6. Vedi PDF per il seguito della bibliografia
2. Ventura A, Magazzù G, Greco L. Duration of Exposure to gluten and risk of autoimmune disorders in patients with coeliac disease. Gastroenterology 1999;11:297-303.
3. Egan CA, O’Loughlin S, Gormally S, et al. Dermatitis herpetiform: a review of fifty-four patients. Ir J Med Sci 1997 Oct- Dec,1666(4):241-4.
4. Reunala T. Dermatitis herpetiform: coelic disease of the skin. Ann Med 1998;30(5):416-8.
5. Loche F, Bazex J. Celiac disease association with cutaneous sarcoidosic granuloma. Med Interne 1997;18(12):975-8.
6. Tasanen K, Raudasoja R, Kallioinemn M, et al. Erythema elevatum diutinum in association with coeliac disease. Br J Dermatol 1997 April,1366(4):624-7.
7. Rodriguez-Serna M, Fortea JM, Perez A, et al. Erythema elevatum diutinum associated with celiac disease: response to a gluten-free diet. Pediatr Dermatol 1993 June;10(2):125-8.
8. Garcia-Patos V, Pujol RM, Barnadas MA, et al. Generalized acquired cutis laxa associated with coeliac disease: evidence of immunoglobulin A deposits on the dermal elastic fibres. Br Dermatol 1996 Jul;135(1):130-4.
9. Thorisdottir K, Camisa C, Tomecki KJ, et al. Necrolytic migratory erythema: a report of three cases. J Am Acad Dermatol 1994 Feb;30(2 Pt 2):324-9.
10. Collin P, Pukkala E, Reunala T. Malignancy and survival in dermatitis herpetiformis: a comparison with coeliac disease. Gut 1996 Apr; 38(4):528-30.
11. Marzano AV, Capsoni F, Berti, et al. Amicrobial pustular dermatosis of cutaneous folds associated with autoimmune disorders: a new entity? Dermatology 1996;193(2):88-93.
12. Kapur A, Isaacs PE, Kelsey PR. Linear IgA dermatosis, coeliac disease, and extraintestinal B cell lymphoma. Gut 1995 Nov;37(5):731-3.
13. Cottafava F, Cosso D. Psoriatic arthritis and celiac in childhood. A case report. Pediatr Med Chir 1991 Jul-Aug;13(4):431-3.
14. Volta U, Bardazzi F, Zauli D, et al. Serological screening for coeliac disease in vitiligo and alopecia areata.Br J Dermatol 1997 May; 136(5):801-2.
15. Barbato M, Viola F, Grillo R, et al. Alopecia and coeliac disease: report of two patients shoowing response to gluten-free diet. Clin Exp Dermatol 1998 Sept;23(5):236-7.
16. Naveh Y, Rosenthal E, Ben-Arieh Y, et al. Celiac disease-associated alopecia in childhood. J Pediatr 1999 Mar;(34483):362-4.
17. Corazza GR, Andreani ML, Venturo N, et al. Coeliac disease and alopecia areata: report of a new association. Gastroenterology 1995 Oct; 109(4):133-7.
18. Michaelsson G, Gerden B. How common is gluten intolerance among patients with psoriasis? Acta Derm Venereol 1991;71(1):90
19. Valdimarsson T, Arnqvist HJ, Toss G, et al. Low circulating insulin-like growth factor-I in coeliac disease and its relation to bone mineral density. Scand J Gastrenterol 1999 Sept; 34(9):904-8.
20. Mora S, Barera G, Beccio S, et al. Bone density and bone metabolism are normal after long-term gluten-free diet in young celiac patient. Am J Gastroenterol 1999 Feb;94(2):398- 403.
21. Kemppainen T; Kroger H, Janatuinen E, et al. Bone recovery after a gluten-free diet: a 5- year follow-up study. Bone 1999 Sept;25(3):355- 60.
22. Kemppainen T, Kroger H, Janatuinen E, et al. Osteoporosis in adult patients with celiac disease. Bone 1999 Mar;24(3):249-55.
23. Meloni GF, Dessole S, Vargiu N, et al. The prevalence of coeliac disease in infertility. Hum Reprod 1999 Nov;14(11):2759-61.
24. Kolho KL, Tiitinen A, Tulppala M, et al. Screening for coeliac disease in women with a history of recurrent miscarriage or infertility. Br J Obstet Gynaecol 1999 Feb;106(2):171-3.
25. Sher KS. Jayanthi V, Probert CS, et al. Infertility, obstetric and gynaecological problems in coeliac sprue. Dig Dis 1994 May- Jun;12(3):186-90.
26. Slot O, Locht H. Arthritis as presenting symptom in silent adult coeliac disease. Two cases and review of the literature. Scand J Rheumatol 2000;29 (4):260-3.
27. Collin P, Vilska S, Heinonen PK, et al: Infertility and coeliac disease. Gut 1996 Sept;39(3): 382-4.
28. Norgard B, Fonager K, Soreensen HT, et al. Birth outcomes of women with celiac disease: a nationwide historical cohort study. Am J Gastroenterol 1999 Sept;94(9):2435-40.
29. Molteni N, Bardella MT, Bianchi PA. Obstetric and gynecological problems in women with untreated celiac sprue. J Clin Gastroenterol 1990 Feb;12(1):37-9.
30. Smecuol E, Maurino E, Vazquez H, et al. Gynaecological and obstetric disorders in coeliac disease: frequent clinical onset during pregnancy or the puerperium. Eur J Gastroenterol Hepatol 1996 Jan;8(1):63-89.
31. Sher KS, Mayberry JF. Female fertility, obstetric and gynaecological history in coeliac disease: a case control study. Acta Paediatr (Suppl) 1996 May;412:76-7.
32. Dondorp AM, de Groot GH. Onset of coeliac disease after a spontaneous miscarriage during a holiday in Australia: coincidance or casual relationship? Neth J Med 1998 Apr;52(4):147-9.
33. Ciacci C, Cirillo M, Auriemma G, et al. Celiac disease and pregnancy outcome. Am J Gastroenterol 1996 Apr;91(4):718-22.
34. Luostarinen L, Pirttila T, Collin P. Coeliac Disease Presenting with Neurological Disorders. Eur Neurol 1999 Oct;42(3):132-5.
35. Hin H, Bird G, Fisher P, et al. Coeliac disease in primary care: case finding study. BMJ 1999;318:164-7.
36. Jokinen J, Peters U, Maki M, et al. Celiac sprue in patients with chronic oral mucosal symptoms. J Clin Gastroenterol 1998 Jan;26 (1):23-6.
37. Curione M, Barbato M, De Biase L, et al. Prevalence of coeliac disease in idiopatic dilated cardiomyopathy. Lancet 1999 Jul 17;354(9174): 222-3.
38. Kull K, Uibo O, Salupere R, et al. High frequency of antigliadin antibodies and absence of antireticulum and antiendomysium antibodies in patients with ulcerative colitis. J Gastroenterol 1999 Feb:34(1):61-5.
39. Ciacci C, Derosa A, de Michele G, et al. Sexual behaviour in untreated and treated celiac patients. Eur J Gastroenterol Hepatol 1998 Aug; 10(8):649-51.
40. Lahteenoja H, Toivanen A, Viander M, et al. Oral mucosal changes in coeliac patients on gluten-free diet. Eur J Oral Sci 1998 Oct;106(5):899-906.
41. Sorensen HT, Thuulstrup AM, Blomqvist P, et al. Risk of primary biliary liver cirrhosis in patients with coeliac disease: Danish and Swedish cohort data. Gut 1999 May;44(5):736-8.
42. Cameron EA, Stewart JA, West KP, et al. Coeliac disease presenting with intra peritoneal haemorrhage. Eur J Gastroenterol Hepatol 1998 Jul:10(7):619-20.
43. Jevon GP, Dimmick JE, Dohil R, et al. Spectrum of gastritis in celiac disease in childhood. Pediatr Dev Pathol 1999 May-Jun;2(3):221-6.
44. Delco F, El-Serag HB, Sonnenberg A. Celiac sprue among US military veterans: associated disorders and clinical manifestation. Dig Dis Sci 1999 May;44(5):966-72.
45. Bhattacharyya A, Patel Mk, Tymms DJ. Coeliac disease in adult: variations on a theme. J R Soc Med 1999 Jun:92(6):286-9.
46. Prussner HT. Detecting celiac disease in your patients. Am Fam Physician 1998 Mar 1;57(5):1023-34,1039-41.
47. Dickey W, McConnel JB. How many hospital visits does it take before celiac sprue is diagnosed? J Clin Gastroenterol 1996 Jul;23(1):21- 3.
48. Varkonyi A, Boda M, Endreffy E, et al. Coeliac disease: always something to discover. Scand J Gastroenterol Suppl 1998;228:122-9.
49. Lubrano E, Ciacci C, Ames PR, et al. The arthritis of coeliac disease: prevalence and pattern in 200 adult patients. Br J Rheumatol 1996 Dec;35(12):1314-8.
50. George EK, Hertzberger-ten Cate, van Suijlekom- Smit LW, et al. Juvenile chronic arthritis and coeliac disease in The Netherlands. Clin Exp Rheumatol 1996 Sep-Oct;14(5):571-5.
51. Paimela L, Kurki P, Leirisalo-Repo M, et al. Gliadin immune reactivity in patients with rheumatoid arthritis. Clin Exp Rheumatol 1995 Sep-Oct;13(5):603-7.
52. Usai P, Boi MF, Piga M, et al. Adult celiac disease is frequently associated with sacroilitis. Dig Dis Sci 1995 Sept;40(9):1906-8.
53. Lepore L, Martelossi S, Pennesi M, et al. Prevalence of celiac disease in patients with juvenile chronic arthritis. J Pediatr 1996 Aug; 129(2):311-3.
54. Falcini F, Ferrari R, Simonini G, et al. Recurrent monoarthritis in an 11-year-old boy with occult coeliac disease. Successful and stable remission after gluten-free diet. Clin Exp Rheumatol 1999 Jul-Aug;17(4):509-11.
55. Carroccio A, Iannitto E, Cavataio F; et al. Sideropenic anemia and celiac disease: one study, two points of view. Dig Dis Sci 1998 Mar; 43(3):673-8.
56. Mahadeva R, Flower C, Shneerson J. Bronchiectasis in association with coelic disease. Thorax 1998 Jun;53(6):527-9.
57. Laudage G, Schirp J. Life threatening epistaxis due to plasma coagulation disorder as a partial manifestation of gluten sensitive enteropathy. Leber Magen Darm 1995 Mar; 25(2):94- 6.
58. Corazza GR, Valentini RA, Andreani ML, et al. Subclinical coeliac disease is a frequent cause of iron-deficiency anaemia. Scand J Gastroenterol 1995 Feb;30(2):153-6. Vedi PDF per il seguito della bibliografia