Pagine elettroniche
L’azatioprina nel trattamento della malattia infiammatoria cronica intestinale in Pediatria
AZATHIOPRINE FOR THERAPY OF IBD IN CHILDHOOD
S. Minisini, S. Facchini, S. Martelossi, A. Ventura
Clinica Pediatrica, IRCCS Burlo Garofolo, Trieste
Ottobre 2001 - pagg. 545 -548
Abstract
28 children with IBD (mean age 14.7) received azathioprine (AZA)
in addition to corticosteroids.
Out of them, 17 are still receiving AZA, 11 had to discontinue the
treatment because of adverse effects or other reasons. With reference
to the Crohn disease, PCDAI decreased, from the beginning
of treatment to the last follow-up, from 26.2 ± 11.4 to 6.5 ± 8.7
(p<0.0001); with reference to recto-colitis, the URC-score passed
from 7.5 ± 1.6 to 3.0 ± 3.3 (p<0.05); the need of corticosteroids
passed from 0.7 mg/kg ± 0.4 to 0.1 ± 0.2 mg/kg (p<0.0001).
Parole chiave
Suggerite dall'AI