Rivista di formazione e aggiornamento professionale del pediatra e del medico di base, fondata nel 1982. In collaborazione con l'Associazione Culturale Pediatri.
Login Abbonamenti Pubblicazioni Carrello Registrazione Perché registrarsi? Contatti

Aggiornamento monografico

PDF

Pseudo-ostruzione intestinale cronica

CHRONIC INTESTINAL PSEUDO-OBSTRUCTION

LICIA PENSABENE, CARLO DI LORENZO

Dipartimento di Pediatria, Divisione di Gastroenterologia Pediatrica, Children's Hospital di Pittsburgh (Pennsylvania, USA)

Settembre 2002 - pagg. 427 -433

Abstract
Chronic intestinal pseudo-obstruction is a rare disabling disorder characterized by recurrent or continuous symptoms and signs of bowel obstruction in the absence of lumen-blocking lesions. The presenting symptoms depend on the regions of the gastrointestinal tract involved, with the small intestine involved almost invariably but with no pathognomonic sign or symptom. There is no single laboratory test that will diagnose pseudo-obstruction: the two most important elements are suspecting the diagnosis and excluding a mechanical obstruction. The most beneficial interventions in patients with pseudo-obstruction are the bowel decompression through the venting ostomies and an effective nutritional support. Therapeutic options also include prokinetic drugs with small bowel transplantation presently being the only definitive cure for patients with pseudo-obstruction.
Parole chiave
Disturbi motori gastrointestinali Enteric neuromuscular diseases Gastrointestinal motor disorders malattie neuromuscolari enteriche Pseudo-obstruction Pseudo-ostruzione
Classificazione MeSH
Nervous System Peripheral Nervous System Autonomic Nervous System Enteric Nervous System (2)
Chemical Actions and Uses Pharmacologic Actions Therapeutic Uses Gastrointestinal Agents
Digestive System and Oral Physiological Phenomena Digestive System Physiological Phenomena Gastrointestinal Motility (7)
Digestive System Diseases Gastrointestinal Diseases Intestinal Diseases Intestinal Obstruction Ileus Intestinal Pseudo-Obstruction (5)
Surgical Procedures, Operative Ostomy
Therapeutics Nutrition Therapy Nutritional Support Parenteral Nutrition Parenteral Nutrition, Total (6)
Small Intestine
Leggi anche
EL Casi indimenticabili
Una atassia acuta in una bambina di 15 mesi
G. Zanella, A.M.C. Galimberti · 2020
Intestinal Pseudo-Obstruction
EL Casi indimenticabili
La sindrome del compasso aortomesenterico
Codrich D, Guida E, Schleef J · 2023
Parenteral Nutrition, Total
Leggi il PDF completo »
Bibliografia
1. Rudolph CD, Hyman PE, Altschuler SM, et al. Diagnosis and treatment of chronic intestinal pseudo-obstruction in children: Report of consensus workshop. J Pediatr Gastroenterol Nutr 1997;24:102-2.
2. Camilleri M. Intestinal dysmotility: does the X-ray resolve the real dilemma? J Pediatr Gastroenterol Nutr 1997;24:100-1.
3. Di Lorenzo C. Pseudo-obstruction: current approaches. Gastroenterology 1999;116:980- 7.
4. Camilleri M, Balm RK, Low PA. Autonomic dysfunction in patients with chronic intestinal pseudo-obstruction. Clin Auton Res 1993;3:95- 100.
5. Cucchiara S. Chronic intestinal pseudo-obstruction: the clinical perspective. J Pediatr Gastroenterol Nutr 2001;32:S21-S22.
6. Verma A, Piccoli DA, Bonelli E, et al. A novel mitochondrial G8313A mutation associated with initial gastrointestinal symptoms and progressive encephaloneuropathy. Pediatr Res 1997;42:448-54.
7. Uc A, Vasiliauskas E, Piccoli DA, Flores AF, et al. Chronic intestinal pseudo-obstruction associated with fetal alcohol syndrome. Dig Dis Sci 1997;42:1163-7.
8. Hyman PE, Di Lorenzo C, Beck D, et al. Discriminating chronic intestinal pseudo-obstruction from Münchausen’s syndrome by proxy in toddlers with intestinal failure. Gastroenterology 1995;108:A619.
9. Stanghellini V, Camilleri M, Malagelada JR. Chronic idiopathic intestinal pseudo-obstruction: clinical and intestinal manometric findings. Gut 1987;28:5-12.
10. Camilleri M. Jejunal manometry in distal subacute mechanical obstruction: significance of prolonged simultaneous contractions. Gut 1989;30:468-75.
11. Di Lorenzo C, Flores AF, Buie T, Hyman PE. Intestinal motility and jejunal feedings in children with chronic intestinal pseudo-obstruction. Gastroenterology 1995;108:1379-85.
12. Di Lorenzo C, Flores AF, Reddy SN, et al. Colonic manometry in children with chronic intestinal pseudo-obstruction. Gut 1993;34: 803-7.
13. Di Lorenzo C, Reddy SN, Flores AF, Hyman PE. Is electrogastrography a substitute for manometric studies in children with functional gastrointestinal disorders? Dig Dis Sci 1997;42:2310-6.
14. Vanderwinden JM, Rumessen JJ, Liu H, et al. Interstitial cells of Cajal in human colon and Hirschsprung’s disease. Gastroenterology 1996;111:901.
15. Kenny SE, Vanderwinden JM, Rintala RJ, et al. Delayed maturation of interstitial cells of Cajal: a new diagnosis of transient neonatal pseudo-obstruction. J Pediatr Surg 1998;33: 94-8.
16. Soudah HC, Hasler W, Owyang C. Effect of octreotide on intestinal motility and bacterial overgrowth in scleroderma. N Engl J Med 1991;325:1461-7.
17. Villarreal J, Sood M, Zangen T, Flores A, et al. Colonic diversion for intractable constipation in children: colonic manometry helps guide clinical decisions. J Pediatr Gastroenterol Nutr 2001;33:588-91.
18. McCallum RW, Chen JDZ, Lin Z, et al. Gastric pacing improves emptying and symptoms in patients with gastroparesis. Gastroenterology 1998;114:456-61.
19. Di Martini A, Rovera GM, Graham TO, et al. Quality of life after small bowel transplantation and among home parenteral nutrition patients. JPEN 1998;22:357-62.