Problemi non correnti
Il trapianto di intestino θ di destra o di sinistra?
INTESTINAL TRANSPLANTATION. RIGHT WING OR LEFT WING?
SERGIO AMARRI
Pediatra, Azienda Ospealiera di Modena, Universitΰ di Modena e Reggio Emilia
Ottobre 2002 - pagg. 509 -512
Abstract
Intestinal transplantation (IT) is an alternative to lifelong total parenteral nutrition (TPN) for cases
of severe intestinal insufficiency with the following characteristics: venous access impossible,
TPN-dependent liver disease, recurrent sepsis, severe and recurrent electrolyte disturbances.
The 5-year survival rate of TPN is over 85%, while IT has a 5-year survival rate of only
50%, although new immunosuppresive drugs and biological therapy have recently improved
the long-term outcome. The overall prognosis of transplanted patients is anyway better than
that of TPN patients who are in waiting list for transplantation. Indications to gut transplantation
are rare. This fact and the need of highly specialised multidisciplinary team work justifies
the existence of only one centre for IT in Italy.
Parole chiave
Suggerite dall'AI
Classificazione MeSH
Bibliografia
1. Cavicchi M, Beau P, Crenn P, et al. Prevalence
of liver disease and contributing factors
in patients receiving home parenteral nutrition
for permanent intestinal failure. Ann Intern
Med 2000;132:525-32.
2. Kaufman SS, Atkinson JB, Bianchi A, et al. Indications for pediatric intestinal transplantation: a position paper of the American Society of Transplantation. Pediatr Transplantation 2001;5:80-7.
3. Reyes J, Bueno J, Kocoshis S, et al. Current status of intestinal transplantation in children. J Pediatr Surg 1998;33:243-54.
4. Nucci AM, Barksdale EM, Beserock N, et al. Long-term nutritional outcome after pediatric intestinal transplantation. J Pediatr Surg 2002;37:460-3.
5. Kosmach-Park B, et al. Physical and psychosocial functioning of as indicators of quality of life following pediatric intestinal transplantation. Transplant Proc 2002. In press.
2. Kaufman SS, Atkinson JB, Bianchi A, et al. Indications for pediatric intestinal transplantation: a position paper of the American Society of Transplantation. Pediatr Transplantation 2001;5:80-7.
3. Reyes J, Bueno J, Kocoshis S, et al. Current status of intestinal transplantation in children. J Pediatr Surg 1998;33:243-54.
4. Nucci AM, Barksdale EM, Beserock N, et al. Long-term nutritional outcome after pediatric intestinal transplantation. J Pediatr Surg 2002;37:460-3.
5. Kosmach-Park B, et al. Physical and psychosocial functioning of as indicators of quality of life following pediatric intestinal transplantation. Transplant Proc 2002. In press.