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Vaccinazione antinfluenzale di massa in età pediatrica: quali evidenze abbiamo?
INFLUENZA VACCINE IN HEALTHY CHILDREN: ANALYSIS OF THE AVAILABLE EVIDENCE
SIMONA DI MARIO1, NICOLA MAGRINI1, SERGIO AMARRI2, DANTE BARONCIANI1, ANNA MARIA MARATA1
1CeVEAS, Centro per la Valutazione dell’Efficacia dell’Assistenza Sanitaria, Azienda USL di Modena
2Unità Operativa di Pediatria, Ospedale di Ravenna
Gennaio 2004 - pagg. 38 -46
Abstract
At the beginning of the 2003-2004 influenza season a debate gained the media attention during
few weeks, focusing the attention of Italian pediatricians and Italian families. Groups and
associations of Italian pediatricians advocated for universal vaccination against influenza virus
for all children irrespective to their general health condition.
In this article we collect and present the available evidence on this topic, in particular on the
epidemiology of influenza and influenza-like syndrome, and on the efficacy, effectiveness and
side effects of influenza vaccination on children. We conclude that there is no evidence to support
such a policy, on the contrary the sparse available data are against it.
We hope that a clear presentation of the evidence can help to conduct the discussion in a more
scientific and less emotional way.
Parole chiave
Suggerite dall'AI
Classificazione MeSH
Bibliografia
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17. Reichert TA, et al. The Japanese experience with vaccinating schoolchildren against influenza, NEJM 2001;344(12):889-96.
18. Neuzil KM, et al. The effect of influenza on hospitalizations, outpatient visits, and courses of antibiotics in children. NEJM 2000;342:225- 231.
19. Monto AS. Epidemiology of viral respiratory infections. Am J Med. 2002;112 Suppl 6A:4S-12S.
20. Olshaker JS. Influenza. Emerg Med Clin North Am. 2003;21(2):353- 61.
21. Cates CJ et al. Vaccines for preventing influenza in people with asthma (Cochrane Review). In: The Cochrane Library, Issue 3, 2003. Oxford: Update Software.
22. Demicheli V et al. Vaccines for preventing influenza in healthy adults (Cochrane Review). In: The Cochrane Library, Issue 3, 2003. Oxford: Update Software.
23. Hoeprich PD. Et al. Infectious Diseases: a treatise of infectious processes. 5th edition. JB Lipincott company edition. Sect. V, chapter 34, pg. 391. English version.
2. http://www.cdcgov/ncidod/diseases/flu/fluvachtm
3. http://www.pediatricsorg/cgi/content/full/110/6/e80
4. http://www.eswiorg/Guidelines_for_Influenza_Vaccination_in_Scandinavia_ cfm
5. http://www.who.int/csr/don/2003_07_03/en/
6. http://www.ministerosalute.it/imgs/C_17_normativa_412_allegato. doc
7. http://www.iss.it/pubblicazioni/opuscoli/influenza
8. http://www.flu.iss.it/files/Prot03.PDF
9. http://www.pnlg.it/news/news0018.php
10. http://www.epicentro.iss.it/focus/influenza/discussione/
11. http://www.epicentro.iss.it/focus/influenza/discussione/Fateh. htm
12. http://www.epicentro.iss.it/focus/influenza/discussione/grandori. htm
13. http://www.epicentro.iss.it/focus/influenza/infl-gallo.htm
14. http://www.epicentro.iss.it/focus/influenza/discussione/barto.- htm
15. http://www.epicentro.iss.it/focus/influenza/discussione/tozzi.htm
16. http://www.epicentro.iss.it/focus/influenza/discussione/arigliano. htm
17. Reichert TA, et al. The Japanese experience with vaccinating schoolchildren against influenza, NEJM 2001;344(12):889-96.
18. Neuzil KM, et al. The effect of influenza on hospitalizations, outpatient visits, and courses of antibiotics in children. NEJM 2000;342:225- 231.
19. Monto AS. Epidemiology of viral respiratory infections. Am J Med. 2002;112 Suppl 6A:4S-12S.
20. Olshaker JS. Influenza. Emerg Med Clin North Am. 2003;21(2):353- 61.
21. Cates CJ et al. Vaccines for preventing influenza in people with asthma (Cochrane Review). In: The Cochrane Library, Issue 3, 2003. Oxford: Update Software.
22. Demicheli V et al. Vaccines for preventing influenza in healthy adults (Cochrane Review). In: The Cochrane Library, Issue 3, 2003. Oxford: Update Software.
23. Hoeprich PD. Et al. Infectious Diseases: a treatise of infectious processes. 5th edition. JB Lipincott company edition. Sect. V, chapter 34, pg. 391. English version.
