Aggiornamento
Il bambino con mastocitosi
PAEDIATRIC MASTOCYTOSIS
Giulia Paloni, Irene Berti
Clinica Pediatrica, IRCCS Burlo Garofolo, Trieste
Marzo 2011 - pagg. 155 -159
Abstract
Mastocytosis is a quite rare but not exceptional condition that affects also children. In
most of the cases it affects only the skin, has a favourable prognosis and resolves spontaneously.
It is characterized by an anomalous increase in mastocytes, which may diffusely
affect all the skin (diffuse cutaneous mastocytosis) or some specific parts of the body
presenting with the symptoms of urticaria pigmentosa or solitary or multiple mastocytoma.
Its symptoms are mostly cutaneous, however, the degranulation of mastocytes with
subsequent release of mediators, especially of histamine, may also determine systemic
symptoms, among which the most typical one is, besides itching, flushing, namely the
temporary reddening of the face and of the upper quadrants of the chest.
Classificazione MeSH
Bibliografia
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Corrispondenza: berti@burlo.trieste.it