Aggiornamento
L’ipereosinofilia
HYPEREOSINOPHILIA
Angela De Cunto1, Cecilia Geraci1, Elisa Rubinato1, Giorgio Longo1, Anna Lorenzati2, Raffaela Mazzone3, Ugo Ramenghi2
1Clinica Pediatrica, IRCCS Pediatrico “Burlo Garofolo”, Trieste
2Struttura Semplice di Ematologia, Dipartimento di Scienze Pediatriche, Università di Torino
3Struttura Semplice di Ematologia e Coagulazione, Dipartimento di Diagnostica, ASO OIRM - S. Anna, Torino
Ottobre 2011 - pagg. 499 -504
Abstract
Blood eosinophilia, especially if found fortuitously, often remains poorly understood. This
article provides a diagnostic approach to hypereosinophilia, focusing on the context in which
these data are found. The diagnostic evaluation of hypereosinophilia with no other
symptoms should consider the level of eosinophils and the duration and trend of hypereosinophilia.
A count greater than 1,500/μl is the proposed cut-off because it is potentially
associated with organ damage. Common infections account for most hypereosinophilias
and are often transient and difficult to define. Other common causes include parasite infections
while lymphoproliferative disorders and hypereosinophilic syndrome genetically
determined are rarer. On the other hand, eosinophilia might also be associated with other
specific conditions such as immunodeficiency disorders or specific eosinophilic disorders.
However, in the latter cases, other specific signs and symptoms, rather than hypereosinophilia
alone command diagnostic iter.
Classificazione MeSH
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Corrispondenza: angela.decunto@libero.it