Farmacoriflessioni
Come si usa il paracetamolo
How to use paracetamol
Anna Di Sessa1, Federico Nappi2, Pierluigi Marzuillo1, Egidio Barbi3
1Dipartimento della Donna, del Bambino e di Chirurgia generale e specialistica, Seconda Università di Napoli
2IRCCS Materno-Infantile “Burlo Garofolo”, Università di Trieste
3IRCCS Materno-Infantile “Burlo Garofolo”, Trieste
Settembre 2014 - pagg. 451 -458
Abstract
Paracetamol (acetaminophen) is one of the most popular and widely used drug for the
treatment of pain and fever in children. Despite its frequent prescription, a full knowledge
of many aspects regarding the mechanism of action is lacking. There are different
paracetamol dosages not only for different route of administration, but also for different
indications (fever and pain treatment); for example the rectal route, even if efficacious as
antipyretic, should be avoided in pain management. This review takes into consideration
aspects dealing with pharmacology, toxicity and therapeutic prescription of paracetamol;
the latest paracetamol toxicity management indications and the guidelines for
fever and pain treatment are reported in order to help physicians to use this drug correctly.
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Corrispondenza: nappifederico@gmail.com