Rivista di formazione e aggiornamento professionale del pediatra e del medico di base, fondata nel 1982. In collaborazione con l'Associazione Culturale Pediatri.
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Problemi speciali

Encefalite da anticorpi anti-NMDAR

From demonic possession to anti-NMDAR encephalitis: that is from the exorcist to the immunomodulatory therapy

Tiziana Granata1, Sara Matricardi2

1UO di Neuropsichiatria Infantile, Fondazione IRCCS Istituto Neurologico “Carlo Besta”, Milano
2Clinica Pediatrica, Università degli Studi “G. D’Annunzio”, Chieti

Dicembre 2014 - pagg. 637 -641

Abstract
Anti-N-metyl-D-aspartate receptor (NMDAR) antibodies encephalitis is a potentially treatable disease characterized by the abrupt onset of a constellation of symptoms resulting from diffuse brain dysfunction. First described in young women as paraneoplastic condition, it has increasingly recognized in children and adolescents without tumor. The paper reviews the main clinical features and differential diagnosis, and provides a diagnostic algorithm as well as a flow chart for treatment in paediatric age.
Parole chiave
IT Anticorpi anti-NMDAR Encefalite autoimmune Sintomi psichiatrici e neurologici
EN Anti-NMDAR antibodies Autoimmune encephalitis Psychiatric and neurological symptoms
Classificazione MeSH
Anti-N-Methyl-D-Aspartate Receptor Encephalitis (9) Autoantibodies (75) Autoimmune Diseases of the Nervous System (15) Immunotherapy (21) Paraneoplastic Syndromes, Nervous System Receptors, N-Methyl-D-Aspartate (3)
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EL Casi indimenticabili
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RI Appunti di Neuropsichiatria
La psicosi e i disturbi psicotici nei bambini e negli adolescenti
Gamberini G, Secci I, Vitiello B. · 2022
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EL Caso contributivo
La sindrome "Cefalea e deficit neurologici transitori con linfocitosi liquorale": un’altra encefalop...
Morelli ME, Carrozzi M · 2021
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"È intelligente ma non si applica": quando è solo una questione di anticorpi
Carnazzo SM, Balconara D, Caruso F, Ruggieri M, Fa · 2023
Paraneoplastic Syndromes, Nervous System/Anti-N-Methyl-D-Aspartate Receptor Encephalitis, Anti-N-Methyl-D-Aspartate Receptor Encephalitis, Autoimmune Diseases of the Nervous System
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Bibliografia

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Corrispondenza: granata@istituto-besta.it