Rivista di formazione e aggiornamento professionale del pediatra e del medico di base, fondata nel 1982. In collaborazione con l'Associazione Culturale Pediatri.
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Vaccinare

Riflessioni sulle coperture vaccinali a 5-6 anni in Italia per il vaccino anti-morbillo, anni 2013-2014

Reflections on measles vaccination coverage among children aged 5-6 years old Italy 2013-2014

Luciano Pinto1, Rocco Russo2

1Società Italiana di Pediatria Preventiva e Sociale
2UO Materno Infantile, ASL Benevento

Novembre 2016 - pagg. 585 -590

Abstract
In Italy, measles vaccine became commercially available in 1976 and the Ministry of Health has been recommending its administration since 1979. The last significant measles epidemic in Italy occurred in the region around Naples, Campania, in 2002 when approximately 41,000 cases were reported: 95% of the reported cases were children under 15 years old, 600 of them had to be hospitalized and among them 16 cases of encephalitis and 4 deaths were reported. Italy, as well as all the other European countries that are member of the World Health Organisation, had committed to eliminate endemic transmission of measles and rubella by 2015; however, even if the incidence of these diseases had decreased, the goal has not been achieved yet. On the 27th January 2016, for the first time the Ministry of Health published the data regarding the coverage for the second dose of the MMR vaccine given at 5-6 years of age for the years 2013 (cohort 2006) and 2014 (cohort 2007). The mean measles vaccination coverage was much lower than 90% (84%) in 2013 and further reduced in 2014 (82.72%), recording peaks of significantly lower percentages in some southern regions. It is therefore evident that this low coverage level results in a substantial number of children susceptible to infection and thus leads to a higher risk of new epidemics. It is therefore necessary to take effective and rapid measures to overcome the widespread mistrust of vaccines, in particular of the measles vaccine, and to reverse the above-mentioned negative trend of the vaccines coverage.
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Bibliografia
1. Ministero della Salute. Morbillo-parotite-rosolia (MPR), trend in diminuzione della copertura vaccinale. 27 gennaio 2016. http:// www.salute.gov.it/portale/news/p3_2_1_1_1.j sp?lingua=italiano&menu=notizie&p=dalministero& id=2420. 2. Ministero della Salute. Piano nazionale per l’eliminazione del morbillo e della rosolia congenita 2010-2015. http://www.salute.gov.it/ imgs/C_17_pubblicazioni_1519_allegato.pdf 3. Sorveglianza Integrata del Morbillo e della Rosolia - ISS-CNESPS, Reparto Epidemiologia delle Malattie Infettive. https://www.iss.it/site/ rmi/morbillo/. 4. Ministero della Salute. Coperture vaccinali (%), calcolate sui riepiloghi inviati dalle Regioni e PP.AA. Anno 2014: 1a dose entro 24 mesi (coorte 2012) aggiornamento 25/01/2016. http://www.salute.gov.it/imgs/C_17_tavole_ 20_allegati_iitemAllegati_16_fileAllegati_it emFile_0_file.pdf. 5. Pinto L, Di Mauro G, Bona G. Un evento previsto: il calo delle coperture vaccinali in Italia nel 2014. Epicentro, 22 ottobre 2015. http: //www.epicentro.iss.it/temi/vaccinazioni/pdf /CVanalisiSipps2015.pdf. 6. Edmunds WJ, van de Heijden OG, Eerola M, Gay NJ. Modelling rubella in Europe. Epidemiol Infect 2000;125(3):617-34. 7. Conferenza Stato-Regioni. Accordo tra il Ministro della Salute, le Regioni e le Province Autonome sul documento recante: Piano nazionale per l’eliminazione del morbillo e della rosolia congenita, 13 novembre 2003. http:// www.ministerosalute.it/imgs/C_17_pubblicazioni_ 730_allegato.pdf. 8. Ciofi Degli Atti ML, Salmaso S, Vellucci L. New measles epidemic in southern Italy: 1217 cases reported to sentinel surveillance, January- May 2003. Euro Surveill 2003;7(27): pii=2253. http://www.eurosurveillance.org/ ViewArticle.aspx?ArticleId=2253. 9. Ministero della Salute: Italia. Decreto 7 aprile 1999. Nuovo calendario delle vaccinazioni obbligatorie e raccomandate per l’età evolutiva. Gazzetta Ufficiale n. 87 del 15 aprile 1999. 10. Filia A, Brenna A, Panà A, Cavallaro GM, Massari M, Ciofi degli Atti ML. Health burden and economic impact of measles-related hospitalizations in Italy in 2002-2003. BMC Public Health 2007;7:169. 11. Spier RE. Perception of risk of vaccine adverse events: a historical perspective. Vaccine 2001;20(Suppl 1):S78- 84. 12. Tickner S, Leman PJ, Woodcock A. Factors underlying suboptimal childhood immunisation. Vaccine 2006;24:7030-6. 13. Salmaso S. Editoriale. Torniamo a parlare di vaccinazioni. Medico e Bambino 2015;34 (5):279-80. 14. ECDC Meeting Report. Individual decision- making and childhood vaccination. Stockholm, Sweden: 24 May 2013. http:// ecdc.europa.eu/en/publications/Publications/ vaccination-individual-decision-makingand- childhood-vaccination.pdf. 15. MacDonald NE; SAGE Working Group on Vaccine Hesitancy. Vaccine hesitancy: Definition, scope and determinants. Vaccine 2015; 33:4161-4. 16. Kennedy A, Lavail K, Nowak G, Basket M, Landry S. Confidence about vaccines in the United States: understanding parents’ perceptions. Health Aff (Millwood) 2011;30(6):1151-9. 17. Chen RT. Vaccine risks: real, perceived and unknown. Vaccine 1999;17:S41-S46. 18. Poland GA, Jacobson RM. Understanding those who do not understand: a brief review of the anti-vaccine movement. Vaccine 2001; 19:2440-5. 19. WHO. Immunization, Vaccines and Biologicals. The immunological basis for immunization series - Module 7: Measles - Update 2009. http://apps.who.int/iris/bitstream/10665/ 44038/1/9789241597555_eng.pdf. 20. Filia A, Bella A, Rota MC, et al. Analysis of national measles surveillance data in Italy from October 2010 to December 2011 and priorities for reaching the 2015 measles elimination goal. Euro Surveill 2013;18(20):pii =20480. Available online: http://www.eurosurveillance. org/ViewArticle.aspx?ArticleId= 20480. 21. European Centre for Disease Prevention and Control. Measles and rubella monitoring, January 2016 – Reporting on January 2015- December 2015 surveillance data and epidemic intelligence data until 31 January 2016. Stockholm: ECDC, 2016. 22. Filia A, Del Manso M, Rota MC, et al. Morbillo & Rosolia News, Marzo 2016. http:// www.epicentro.iss.it/problemi/morbillo/bollettino/ RM_News_2016_25.pdf. 23. Butler R, MacDonald NE; SAGE Working Group on Vaccine Hesitancy. Diagnosing the determinants of vaccine hesitancy in specific subgroups: The Guide to Tailoring Immunization Programmes (TIP). Vaccine 2015;33: 4176-9. 24. WHO. Report of the SAGE Working Group on Vaccine Hesitancy. http://www.who.int/ immunization/sage/meetings/2014/october/ SAGE_working_group_revised_report _vaccine_hesitancy.pdf?ua=1vi. 25. AIFA. Cresce a livello globale l’opposizione ai vaccini: l’OMS analizza il fenomeno ed esplora le strategie per affrontarlo. 31 agosto 2015. 26. Dubé E, Gagnon D, Nickels E, Jeram S, Schuster M. Mapping vaccine hesitancy-country- specific characteristics of a global phenomenon. Vaccine 2014;32:6649-54. 27. Commissione Vaccini della SIAIP, Gruppo di Lavoro Vaccini e Vaccinazioni della SIPPS. Dobbiamo cambiare per mantenere elevate le coperture vaccinali in Italia! - RIAP 2015;19(3): 26-34. http://www.riaponline.it/wp-content/ uploads/2015/09/ RivRiap3_15. pdf. 28. European Centre for Disease Prevention and Control. Vaccine hesitancy among healthcare workers and their patients in Europe - A qualitative study. Stockholm: ECDC, 2015. 29. Odone A, Fara GM, Giammaco G, Blangiardi F, Signorelli C. The future of immunization policies in Italy and in the European Union: The Declaration of Erice. Hum Vaccin Immunother 2015;11(5):1268-71. 30. Leask J, Kinnersley P, Jackson C, Cheater F, Bedford H, Rowles G. Communicating with parents about vaccination: a framework for health professionals. BMC Pediatr 2012;12: 154. 31. Piccirilli G, Lazzarotto T, Chiereghin A, Serra L, Gabrielli L, Lanari M. Spotlight on measles in Italy: why outbreaks of a vaccinepreventable infection continue in the 21st century. Expert Rev Anti Infect Ther 2015;13(3): 355-62. 32. Nowak GJ, Gellin BG, MacDonald NE, Butler R; SAGE Working Grou p on Vaccine Hesitancy. Addressing vaccine hesitancy: The potential value of commercial and social marketing principles and practices. Vaccine 2015;33: 4204-11. 33. Wheeler M, Buttenheim AM. Parental vaccine concerns, information source, and choice of alternative immunization schedules. Hum Vaccin Immunother 2013;9(8):1782-9. 34. Salmon DA, Haber M, Gangarosa EJ, Phillips L, Smith NJ, Chen RT. Health consequences of religious and philosophical exemptions from immunization laws: individual and societal risk of measles. JAMA 1999;282:47-53. 35. Feikin DR, Lezotte DC, Hamman RF, Salmon DA, Chen RT, Hoffman RE. Individual and community risks of measles and pertussis associated with personal exemptions to immunization. JAMA 2000;284:3145-50. 36. Omer SB, Enger KS, Moulton LH, et al. Geographic clustering of nonmedical exemptions to school immunization requirements and associations with geographic clustering of pertussis. Am J Epidemiol 2008;168:1389- 96. 37. Bätzing-Feigenbaum J, Pruckner U, Beyer A, et al. Spotlight on measles 2010: Preliminary report of an ongoing measles outbreak in a subpopulation with low vaccination coverage in Berlin, Germany, January-March 2010. Euro Surveill 2010;15:pii=19527. Available online: http://www.eurosurveillance.org/ViewArticle. aspx?ArticleId=19527. 38. Filia A, Bella A, Cadeddu G, et al. Extensive Nosocomial Transmission of Measles Originating in Cruise Ship Passenger, Sardinia, Italy, 2014. Emerg Infect Dis 2015;211:444-6. 39. European Centre for Disease Prevention and Control. Outbreak of measles linked to a dog show in Slovenia, 8-9 November 2014 - 2 December 2014. Stockholm: ECDC, 2014. 40. European Centre for Disease Prevention and Control. Outbreak of measles in France, Haut-Rhin, April 2015. Stockholm: ECDC, 2015. 41. CDC Measles - United States, January 4- April 2, 2015. MMWR 2015;64;373-6. 42. Comitato Nazionale per la Bioetica Mozione: L’importanza delle vaccinazioni 24/04/ 2015. http://presidenza.governo.it/bioetica/ mozioni/index.html. 43. Salmaso S. Cambiamenti delle politiche vaccinali: la California sancisce la fine dell’esenzione per opinioni personali. Epicentro, 3 settembre 2015. http://www.epicentro.iss.it/ temi/vaccinazioni/California2015.asp. 44. Pinto L, Bona G, Di Mauro G. Vaccinazioni ed interesse superiore del fanciullo. Epicentro, 18 febbraio 2016. http://www.epicentro. iss.it/temi/vaccinazioni/indice.asp. RIPPS 2016, XI, 1, 64-7.

Corrispondenza: lucianopinto@virgilio.it