Problemi speciali
Sanguinamenti genitali nella bambina:
quante diagnosi per un solo sintomo!
Female genital bleending in paediatric age: so many diagnoses for a single symptom!
Maria Chiara Lucchetti
Chirurgia Pediatrica, Alta Specializzazione in Ginecologia Pediatrica, IRCCS Ospedale Pediatrico “Bambino Gesù”, Roma
Febbraio 2017 - pagg. 93 -98
Abstract
Genital bleedings in paediatric age are always a cause of parental distress that also involve
the paediatrician who is expected to give a prompt diagnosis that is rarely easy to
find. The spectrum of possible differential diagnoses is wide and variable, going from accidental
or non-accidental local injuries to infections and up to neoplastic lesions.
Anyway, it has to be reminded that a good proportion of these bleedings remains “of unknown
origin” even when properly approached and will not find any reasonable causative
agent even at the end of the most accurate work-up.
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Bibliografia
1 Söderström HF, Carlsson A, Börjesson A,
Elfving M. Vaginal bleeding in prepubertal
girls: etiology and clinical management. J Pediatr
Adolesc Gynecol 2016;29(3):280-5.
2 Hill NC, Oppenheimer LW, Morton KE.
The aetiology of vaginal bleeding in children.
A 20‐year review. Br J Obstet Gynecol 1989;
96(4):467-70.
3 Imai A, Furui, T, Iida K, Tamaya T. Gynecologic
tumors and symptoms in childhood and
adolescence. Curr Opin Obstet Gynecol 2001;
13(5):469-73.
4 Brosens I, Benagiano G. Clinical significance
of neonatal menstruation. Eur J Obstet Gynecol
Reprod Biol 2016;196:57-9.
5 Puttemans P, Benagiano G, Gargett G, Romero
R, Guo SW, Brosens I. Neonatal uterine
bleeding as a biomarker for reproductive disorders
during adolescence: a worldwide call
for systematic registration by nurse midwife. J
Mater Fetal Neonatal Med 2016; 18:1-3.
6. Semaan A, Klein T, Vahdad MR, Boemers
TM, Pohle R. Severe vaginal burns in a 5-
year-old girl due to an alkaline battery in the
vagina. J Pediatr Adolesc Gynecol 2015;28
(5):e147-8.
7. Griffin K, Brent R, Vollenhoven B, Swanson
AE. Vaginal burn from alkaline battery in an 8-
year-old. J Pediatr Adolesc Gynecol 2015;
28(4):e99-100.
8. Jacobs L, Gilliam A, Khavari N, Bass D.
Association between lichen sclerosus and celiac
disease: a report of three pediatric cases.
Pediatr Dermatol 2014;31(6):e128-31.
9. Bercaw-Pratt JL, Boardman LA, Simms-
Cendan JS. Clinical recommendations: pediatric
lichen sclerosus. J Pediatr Adolesc Gynecol
2014;27(2):111-6.
10. Papanikolaou A, Michala L. Autonomous
ovarian cysts in prepubertal girls. How aggressive
should we be? A review of the Literature.
J Pediatr Adolesc Gynecol 2015;28
(5):292-6.
11. Agopiantz M, Journeau P, Lebon-Labich
B, et al. McCune-Albright syndrome, natural
history and multidisciplinary management in
a series of 14 pediatric cases. Ann Endocrinol
(Paris) 2016;77(1):7-13.
12. Nikumbh DB, Suryawanshi KH, Chitale
AM, Pagare P, Surana A. Ovarian juvenile
granulosa cell tumour in childhood: uncommon
gynecological malignancy. J Clin Diagn
Res 2014;8(10):FL01-2.
13. Wu H, Pangas SA, Eldin KW, et al. Juvenile
granulosa cell tumor of the ovary: a clinicopathologic
study. J Pediatr Adolesc Gynecol
2017;30(1):138-43.
14. Nella AA, Kaplowitz PB, Ramnitz MS,
Nandagopal R. Benign vaginal bleeding in 24
prepubertal patients: clinical, biochemical
and imaging features. J Pediatr Endocrinol
Metabol 2014;27(9-10):821-5.
15. Ejaz S, Lane A, Wilson T. Outcome of isolated
premature menarche: a retrospective
and follow-up study. Horm Res Paediatr 2015;
84(4):217-22.
16. McQuillan SK, Grover SR, Pyman J, Jayasinghe
YL. Literature review of benign müllerian
papilloma contrasted with vaginal rhabdomyosarcoma.
J Pediatr Adolesc Gynecol
2016;29(4):333-7.
17. Walterhouse DO, Pappo AS, Meza JL, et
al. Shorter-duration therapy using vincristine,
dactinomycin, and lower-dose cyclophosphamide
with or without radiotherapy for patients
with newly diagnosed low-risk rhabdomyosarcoma:
a report from the Soft Tissue
Sarcoma Committee of the Children's Oncology
Group. J Clin Oncol 2014;32(31):3547-52.
18. Breneman J, Meza J, Donaldson SS, et al.
Local control with reduced-dose radiotherapy
for low-risk rhabdomyosarcoma: a report
from the Children’s Oncology Group
D9602 study. Int J Radiat Oncol Biol Phys
2012;83(2):720-6.
19. Mousavi A, Akhavan S. Sarcoma botryoides
(embryonal rhabdomyosarcoma) of the
uterine cervix in sisters. J Gynecol Oncol
2010;21(4):273-5.
20. Villella JA, Bogner PN, Jani-Sait SN,
Block AM, Lele S. Rhabdomyosarcoma of
the cervix in sisters with review of the literature.
Gynecol Oncol 2005;99(3):742-8.
21. Bhatt MD, Braga LH, Stein N, Terry J,
Portwine C. Vaginal yolk sac tumor in an infant:
a case report and literature review of the
last 30 years. J Pediatr Hematol Oncol 2015;
37(5):e336-40.
Corrispondenza: mchiara.lucchetti@opbg.net