Problemi speciali
Scorbuto 2017 attraverso i casi
Scurvy in 2017 through cases
Ester Conversano1, Rosalba Bergamaschi2, Giulia Ingrasciotta3, Aanna Martoni4, Sara Monti4, Marco Cattalini3
1Università di Trieste
2Azienda Ospedaliero-Universitaria Policlinico “Sant’Orsola-Malpighi”, Bologna
3Università di Brescia
4Università di Bologna
Giugno 2017 - pagg. 365 -370
Abstract
Scurvy is an uncommon presentation of vitamin deficiency that in our century is becoming
more and more common, especially in patients with cognitive disorder. Being an uncommon
disease, diagnosis is often delayed and can lead to unnecessary complex workup.
It can be avoided by precocious diagnosis, knowing typical and rare manifestation. Clinical
presentation is very variable and includes gingival, cutaneous, and musculoskeletal
involvement that is pathognomonic. Laboratory diagnosis can be difficult to obtain
whereas the clinical response after ascorbic acid supplementation leads to scurvy diagnosis.
Classificazione MeSH
Contenuto riservato
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Bibliografia
1. Camarena V, Wang G. The epigenetic role
of vitamin C in health and disease. Cell Mol Life
Sci 2016;73(8):1645-58.
2. Mayor S. Sixty seconds on... scurvy. BMJ
2016;355:i6540.
3. Duggan C, Westra SJ, Rosenberg AE. Case
23-2007: a 9-year-old boy with bone pain, rash,
and gingival hypertrophy. N Engl J Med 2007;
357(4):392-400.
4. Agarwal A, Shaharyar A, Kumar A, Bhat
MS, Mishra M. Scurvy in pediatric age group.
A disease often forgotten? J Clin Orthop Trauma
2015;6(2):101-7.
5. Hafez D, Saint S, Griauzde J, Mody R, Meddings
J. Clinical problem-solving. A deficient
diagnosis. N Engl J Med 2016;374(14):1369-74.
6. Seya M, Handa A, Hasegawa D, Matsui T,
Nozaki T. Scurvy: from a selective diet in children
with developmental delay. J Pediatr 2016;
177:331.
7. Ferrari C, Possemato N, Pipitone N, Manger
B, Salvarani C. Rheumatic manifestations
of scurvy. Curr Rheumatol Rep 2015;17(4):26.
8. Pimentel L. Scurvy: historical review and
current diagnostic approach. Am J Emerg
Med 2003;21(4):328-32.
9. Duvall MG, Pikman Y, Kantor DB, et al. Pulmonary
hypertension associated with scurvy
and vitamin deficiencies in an autistic child.
Pediatrics 2013;132(6);e1699-703.
10. Gulko E, Collins LK, Murphy RC,
Thornhill BA, Taragin BH. MRI findings in pediatric
patients with scurvy. Skeletal Radiol
2015;44(2):291-7.
11. Tafaghodi F, Aghighi Y, Rokni Yazdi H,
Shakiba M, Adibi A. Predictive plain X-ray findings
in distinguishing early stage acute
lymphoblastic leukemia from juvenile idiopathic
arthritis. Clin Rheumatol 2009;28(11):
1253-8.
12. Dey F, Möller A, Kemkes-Matthes B, et al.
Reduced platelet aggregation in a boy with
scurvy. Klin Padiatr 2012;224(7):448-452.
13. Jacobsen A, DeNiro K. Rash and arthralgias
in a teenager with autism. JAMA Pediatr
2017;171(1):89-90.
14. Weinstein M, Babyn P, Zlotkin S. An orange
a day keeps the doctor away: scurvy in the
year 2000. Pediatrics 2001;108(3):E55.
Corrispondenza: esterconversano@gmail.com
