Interferenti endocrini e salute dei bambini

1. ENV/JM/MONO - Environment Directorate Joint Meeting of the Chemicals Committee and the Working Party on Chemicals, Pesticides and Biotechnology. Detailed review paper on the state of the science on novel in vitro and in vivo screening and testing methods and endpoints for evaluating endocrine disruptors. 2012. 2. Diamanti-Kandarakis E, Bourguignon JP, Giudice LC, et al. Endocrine-disrupting chemicals: an Endocrine Society scientific statement. Endocrine Rev 2009;30(4):293-342. 3. Bergman A, Heindell JJ, Jobling S, Kidd KA, Zoeller RT (eds). The state of the science of endocrine disrupting chemicals-2012. United Nations Environment Programme (UNEP) and World Health Organization (WHO). 2013. 4. Darbre PD. Endocrine disruption and human health. Oxford (UK): Academic Press (Elsevier), 2015. 5. World Health Organization. Polychlorinated biphenyls and terphenyls. Environmental Health Criteria 140. Geneva: World Health Organization, 1992. 6. Janjua NR, Mortensen GK, Andersson AM, Kongshoj B, Skakkebaek NE, Wulf HC. Systemic uptake of diethyl phthalate, dibutyl phthalate, and butyl paraben following whole-body topical application and reproductive and thyroid hormone levels in humans. Environ Sci Technol 2007;41(15):5564-70. 7. Janjua NR, Frederiksen H, Skakkebaek NE, Wulf HC, Andersson AM. Urinary excretion of phthalates and paraben after repeated whole- body topical applications in humans. Int J Androl 2008;31(2):118-30. 8. Johnson AC, Dumont E, Williams RJ, Oldenkamp R, Cisowska I, Sumpter JP. Do concentrations of ethinyl-estradiol, estradiol, and diclofenac in European rivers exceed proposed EU environmental quality standards? Environ Sci Technol 2013;47(21):12297-304. 9. Publications of the secretariat of the Stockholm convention on persistent organic pollutants. www.pops.int. 10. Scarth JP. Modulation of the growth hormone- insulin-like growth factor (GH-IGF-1) axis by pharmaceutical, nutraceutical and environmental xenobiotics: an emerging role for xenobiotic-metabolizing enzymes and the transcription factors regulating their expression. A review. Xenobiotica 2006;36(2-3):119-218. 11. Wu X, Zhang N, Lee MM. The influence of endocrine disruptors on male pubertal timing. In: Diamanti-Kandarakis E, Gore AC (eds). Endocrine disruptors and puberty. New York, NY: Humana Press, Springer, 2012. 12. Cranefield PF. The discovery of cretinism. Bull Hist Med 1962;36:489-511. 13. Miller MD, Crofton KM, Rice DC, Zoeller RT. Thyroid-disrupting chemicals: interpreting upstream biomarkers of adverse outcomes. Environ Health Perspect 2009;117(7): 1033-41. 14. Gutleb AC, Cambier S, Serchi T. Impact of endocrine disruptors on the thyroid hormone system. Horm Res Pediatr 2016;86(4):271-8. 15. Ten S, New M, Maclaren N. Addison’s disease 2001. J Clin Endocrinol Metab 2001;86 (7):2909-22. 16. Harvey PW, Everett DJ, Springall CJ. Adrenal toxicology: a strategy for assessment of functional toxicity to the adrenal cortex and steroidogenesis. J Appl Toxicol 2007;27:103-15. 17. Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol 2006;26(3):191- 7. 18. Moreira AC, Silva AM, Santos MS, Sardao VA. Phytoestrogens as alternative replacement therapy in menopause: what is real, what is unknown? J Steroid Biochem Mol Biol 2014; 143C:61-71. 19. Darbre PD, Fernandez MF. Environmental oestrogens and breast cancer: long-term low-dose effects of mixtures of varied chemical combinations. J Epidemiol Community Health 2013;67(3):203-5. 20. World Health Organization. Endocrine disrupters and child health: possible developmental early effects of endocrine disrupters on child health. Geneva, Switzerland: WHO 2012. 21. Kaprio J, Rimpela A, Winter T, Viken RJ, Rimpela M, Rose RJ. Common genetic influences on BMI and age at menarche. Hum Biol 1995;67(5):739-53. 22. Colón I, Caro D, Bourdony CJ, Rosario O. Identification of phthalate esters in the serum of young Puerto Rican girls with premature breast development. Environ Health Perspect 2000;108(9):895-900. 23. Deodati A, Sallemi A, Maranghi F, et al. Serum levels of polybrominated diphenyl ethers in girls with premature thelarche. Horm Res Paediatr 2016;86(4):233-9. 24. Sjödin A, Jones RS, Focant JF, et al. Retrospective time-trend study of polybrominated diphenyl ether and polybrominated and polychlorinated biphenyl levels in human serum from the United States. Environ Health Perspect 2004;112(6):654-8. 25. Lorber M. Exposure of Americans to polybrominated diphenyl ethers. J Expo Sci Environ Epidemiol 2008;18(1):2-19. 26. Chao HR, Wang SL, Lin LY, Lee WJ, Papke O. Placental transfer of polychlorinated dibenzo- p-dioxins, dibenzofurans, and biphenyls in Taiwanese mothers in relation to menstrual cycle characteristics. Food Chem Toxicol 2007;45(2):259-65. 27. Farr SL, Cooper GS, Cai J, Savitz DA, Sandler DP. Pesticide use and menstrual cycle characteristics among premenopausal women in the Agricultural Health Study. Am J Epidemiol 2004;160(12):1194-204. 28. Vos T, Flaxman AD, Naghavi M, et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012;380(9859): 2163-96. 29. Sharpe RM. Pathways of endocrine disruption during male sexual differentiation and masculinisation. Best Pract Res Clin Endocrinol Metab 2006;20(1):91-110. 30. Woods HF (chairman). Phytoestrogens and health. London: Food Standards Agency Publication. Crown Copyright 2003. http:// cot.food.gov.uk/pdfs/phytoreport0503. 31. Palmer JR, Herbst AL, Noller KL, et al. Urogenital abnormalities in men exposed to diethylstilboestrol in utero: a color study. Environ Health 2009;8(37):1-6. 32. Mantovani A. Endocrine disrupters and the safety of food chain. Horm Res Pediatr 2016;86(4):279-88. 33. Zoeller RT, Brown TR, Doan LL, et al. Endocrine- disrupting chemicals and public health protection: a statement of principles from The Endocrine Society. Endocrinology 2012;153(9):4097-110.