Vaccinare
Vaccinazioni in pazienti fragili:
facciamo il punto della situazione
Immunisation in fragile patients: let's take stock of the situation
Luisa Abbagnato, Angelo Selicorni
UOC di Pediatria, Presidio di San Fermo, ASST Lariana, Como
Ottobre 2018 - pagg. 501 -507
Abstract
Immunisation and disability are inextricably linked. It is well known that vaccinations can
eliminate or mitigate some preventable diseases that can cause disability when severely
expressed. Moreover, the issue about immunisation of a child affected by congenital or
acquired disability, for whom prevention of the more common infectious diseases can be
also more important than for an healthy child, is still debated. Unfortunately, there are
too many uncertainties and little knowledge about the real (limited) contraindications and
the many absolute indications. This report tries to summarize this complex issue describing
the necessary precautions that should be shared and to suggest some final food for thought
to improve the situation.
Parole chiave
Suggerite dall'AI
Classificazione MeSH
Contenuto riservato
Per leggere l'articolo completo è necessario effettuare il login.
Non sei ancora registrato? Registrati
Bibliografia
1. UNICEF. Disability Prevention Effort and
Disability Rights: Finding Common Ground
on Immunization Efforts. UNICEF Working
Paper developed with support from Leonard
Cheshire Disability and Inclusive Development
Centre, Unuversity College London.
2. WHO. World Report on Disability, Geneva
+ United Nation. Convention on the Rights of
Person with Disadilities, 2011.
3. Valentini D, Bianchi S, Di Camillo C, et al.
Fatal varicella pneumonia in an unvaccinated
child with Down syndrome - a case report. Ital
J Pediatr 2016;42:99.
4. Blanton L, Peacock G, Cox C, et al. Neurologic
disorder among pediatric deaths associated
with the 2009 pandemic influenza. Pediatrics
2012;130:390-6.
5. Wong KK, Jain S, Blanton L, et al. Influenza-
associated pediatric deaths in the United
States, 2004-2012. Pediatrics 2013;132:796-804.
6. Perez-Padilla R, Fernanāndez R, Garcia-Sancho
C et al. Pandemic (H1N1) 2009 virus and
Down syndrome patients. Emerg Infect Dis
2010;16(8):1312-4.
7. Smith M, Peacock G, Uyeki TM, Moore C.
Influenza vaccination in children with neurologic
or neurodevelopmental disorders. Vaccine
2015;33(20):2322-7.
8. Tanabe T, Tagawa T, Arai H, et al. Survey
of Japanese pediatricians on vaccination of
children with neurological disorders. Pediatr
Int 2011;53:626-9.
9. Cerutti M, De Lonlay P, Menni F, et al. Vaccination
coverage of patients with inborn errors
of metabolism and the attitudes of their parents
towards vaccines. Vaccine 2015;33:6520-4.
10. Esposito S, Cerutti M, Milani D, Menni F,
Principi N. Vaccination coverage of children
with rare genetic diseases and attitudes of
their parents toward vaccines. Hum Vaccin
Immunother 2016;12(3):801-5.
11. Esposito S, Selicorni A, Daleno C, et al. Immunogenicity,
safety and tolerability of monovalent
2009 pandemic influenza A/H1N1
MF59-adjuvanted vaccine in children and adolescents
with Williams or Cornelia de Lange
syndrome. Hum Vaccin 2011;6(7):613-7.
12. Esposito S, Salvini F, Menni F, et al. Preliminary
data on immunogenicity, safety and
tollerability of trivalent inactivated influenza
vaccine in children with inborn errors of metabolism
at risk of decompensation. Vaccine
2013;31:5149-51.
13. ISS. Guida alle controindicazioni alle vaccinazioni.
Quinta edizione, luglio 2017.
14. American Academy of Pediatrics. Red
Book 2015 - The report of the Committee on
Infectious Diseases. 30th ed. Elk Grove Village
(IL), 2015.
15. Shearer WT, Fleisher TA, Buckley RH, et
al. Recommendations for live viral and bacterial
vaccines in immunodeficient patients and
their close-contacts: Medical Advisory Committee
of the Immune Deficiency Foundation.
J Allergy Clin Immunol 2014;133(4):961-6.
16. Moschese V, Capristo C, Cardinale F, et
al. La profilassi anti-infettiva nelle immunodeficienze
primitive. Rivista di immunologia e Allergologia
Pediatrica RIAP 2011;2:39-51.
17. Azzari C. Le vaccinazioni nelle immunodeficienze
primitive. AIP, 2016.
18. LICE, SINP, SINPIA e SIP (a cura di). Linee
guida su epilessia e vaccinazioni, 2011.
19. Esposito S, Bruno C, Berardinelli A, et al.
Vaccination recommendations for patients
with neuromuscular disease. Vaccine 2014;32:
5893-900.
20. Klein NP, Aukes L, Lee J, et a. Evaluation
of immunization rates and safety among children
with inborn errors of metabolism. Pediatrics
2011;127(5).
21. Kingsley JD, Varman M, Chatterjee A,
Kingsley RA, Roth KS. Immunizations for patients
with metabolic disorders. Pediatrics
2006;118:e460-e470.
22. Menni F, Chiarelli G, Sabatini C, et al. Vaccination
in children with inborn errors of metabolism.
Vaccine 2012;30:7161-4.
Corrispondenza: angelo.selicorni61@gmail.com
