L'angolo dell'immunologo
Induzione orale di tolleranza immunologica: più teoria che pratica
TARCISIO NOT, EMANUELE BURATTI, IRENE BERTI, CHIARA TREVISIOL, ALBERTO TOMMASINI
Laboratorio Immunologico, Istituto di Clinica Pediatrica, IRCCS “Burlo Garofolo”, Trieste
Gennaio 1998 - pagg. 53 -54
Parole chiave
Classificazione MeSH
Bibliografia
1. Hanson et al: Inhibition of specific immune responses by feeding
protein antigens. II. Effects of prior passive and active immunization. J
Immunol 122, 2261, 1977.
2. Elson CO, Ealding W: Cholera toxin feeding did not induce oral tolerance in mice and abrogated oral tolerance to unrelated protein antigen. J Immunol 133, 2892-2897, 1984.
3. MacPherson A et al: Mucosal antibodies in inflammatory bowel disease are directed against intestinal bacteria. Gut 38, 365-375, 1996.
4. Weiner Hl: Oral tolerance: immune mechanisms and treatment of autoimmune diseases. Immunol Today 18, 335-343, 1997.
5. Weiner HL et al: Antigen-driven bystander suppression after oral administration of antigens. J Exp Med 74, 791-798, 1991.
6. Weiner et al: Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 265, 1237- 1240, 1994.
7. Roncarolo MG et al: Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells. J Exp Med 184, 19-29, 1996.
8. Meuer S et al: T cells of the human intestinal lamina propria are high producers of interleukin-10. Gut 41, 215-220, 1997.
9. Duchmann R et al: Tolerance towards resistent intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin-10 or antibodies to interleukin-12. Eur J Immuol 26, 934- 938, 1996.
10. Van Deventer SJ et al: Multiple doses of interleukin 10 in steroidrefractory Crohn’s disease. Crohn’s Disease Study Group. Gastroenterology 113, 383-389, 1997.
11. Hafler DA et al: Induction of circulating myelin basic protein and proteolipid protein specific transforming growth factor-b1-secreting Th3 T Cells by oral administration of myelin in multiple sclerosis patients. J Clin Invest 98, 70-77, 1996.
12. Ma SW et al: Transgenic plants expressing autoantigens fed to mice to induce oral immune tolerance. Nat Med 3, 793-796, 1997.
13. Koga Y et al: The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction. J Immunol 159, 1739-1745, 1997.
14. Moreau MC, Gaboriau-Routhiau VG: Gut flora recovery of oral tolerance to ovalbumin in mice after transient breackdown mediated by Cholera toxin or Escherichia coli heat-labile enterotoxin. Pediatr Res 39, 4, 1996.
2. Elson CO, Ealding W: Cholera toxin feeding did not induce oral tolerance in mice and abrogated oral tolerance to unrelated protein antigen. J Immunol 133, 2892-2897, 1984.
3. MacPherson A et al: Mucosal antibodies in inflammatory bowel disease are directed against intestinal bacteria. Gut 38, 365-375, 1996.
4. Weiner Hl: Oral tolerance: immune mechanisms and treatment of autoimmune diseases. Immunol Today 18, 335-343, 1997.
5. Weiner HL et al: Antigen-driven bystander suppression after oral administration of antigens. J Exp Med 74, 791-798, 1991.
6. Weiner et al: Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 265, 1237- 1240, 1994.
7. Roncarolo MG et al: Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells. J Exp Med 184, 19-29, 1996.
8. Meuer S et al: T cells of the human intestinal lamina propria are high producers of interleukin-10. Gut 41, 215-220, 1997.
9. Duchmann R et al: Tolerance towards resistent intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin-10 or antibodies to interleukin-12. Eur J Immuol 26, 934- 938, 1996.
10. Van Deventer SJ et al: Multiple doses of interleukin 10 in steroidrefractory Crohn’s disease. Crohn’s Disease Study Group. Gastroenterology 113, 383-389, 1997.
11. Hafler DA et al: Induction of circulating myelin basic protein and proteolipid protein specific transforming growth factor-b1-secreting Th3 T Cells by oral administration of myelin in multiple sclerosis patients. J Clin Invest 98, 70-77, 1996.
12. Ma SW et al: Transgenic plants expressing autoantigens fed to mice to induce oral immune tolerance. Nat Med 3, 793-796, 1997.
13. Koga Y et al: The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction. J Immunol 159, 1739-1745, 1997.
14. Moreau MC, Gaboriau-Routhiau VG: Gut flora recovery of oral tolerance to ovalbumin in mice after transient breackdown mediated by Cholera toxin or Escherichia coli heat-labile enterotoxin. Pediatr Res 39, 4, 1996.