Problemi correnti
Linfoadeniti da micobatteri non tubercolari
NON-TUBERCOLOUS MYCOBACTERIAL LYMPHADENITIS
F. MASSEI, M. NARDI, C. BAGLIONI1, C. FAVRE, M. MASSIMETTI, P. MACCHIA
Dipartimento di Medicina della Procreazione e dell’Età Evolutiva, Divisione di Pediatria 1°, Università di Pisa
1Dipartimento di Patologia Sperimentale, Biotecnologie Mediche, Infettivologia ed Epidemiologia
Scuola di Specializzazione in Igiene e Medicina Preventiva, Università di Pisa
Febbraio 1999 - pagg. 95 -101
Abstract
Non-tubercolous mycobacteria (NTMB) are responsible for 6,2% of all diseases due to mycobacteria
in Italy. Lymphadenitis is the most common infection due to NTBs. Differential
diagnosis must be made with tubercolous lymphadenitis, cat-scatch disease, and toxoplasmosis.
Once the diagnosis is confirmed (skin test for NTMB is suggested) surgical excision
is the recommended treatment. Antibiotics are indicated only in patients where surgery can
not be complete or in immunocompromised patients. Nine paediatric cases are described.
Classificazione MeSH
Bibliografia
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3. American Academy of Pediatrics. Committee on Infectious Diseases: Micobatteri nontubercolari. In: Report of the Committee on Infectious Diseases (Red Book), ed. Italiana, 1997, pp. 348, 535.
4. Cross JT, Jacobs RF: Other Mycobacteria. In: Textbook of Pediatric Infectious Disease. Feigin RD, Cherry JD (a cura di), WB Saunders Co, 1998, p. 1239.
5. Margileth AM: Nontuberculous (Atypical) Mycobacterial Disease. In: Current Pediatric Therapy, Burg FD, Wald ER, Ingelfinger JR, Polin RA (a cura di), WB Saunders Co, 1996, p. 609.
6. Deriu GM, Tortoli E, Massei F, Caroli G: Un incontro col Mycobacterium malmoense. L’Igiene Moderna 103, 335-342, 1995.
7. Huebner RE, Schein MF, Cauthen GM: Usefulness of skin testing with mycobacterial antigens in children with cervical lymphadenopathy. Pediatr Infect Dis J 11, 450-55, 1992.
8. Del Beccaro MA, Mendelman PM, Nolan C: Diagnostic usefullness of mycobacterial skin test antigens in childhood lymphadenits. Pediatr Infect Dis J 8, 206-210, 1989.
9. Clark J, Magee GJ, Cant JA: Non-tuberculous mycobacterial lymphadenopathy. Arch Dis Child 72, 165-166, 1995.
10. Vecchi V, Burnelli R: Linfoadenopatie nell’infanzia: studio epidemiologico e approccio diagnostico-terapeutico. Edyt Symposia Pediatria e Neonatologia 1, 129-141, 1997.
11. Marseglia GL, Marone P: Le infezioni da micobatteri non tubercolari. In: Infettivologia Pediatrica, UTET, 1997, p. 55.
12. Chadwick GE, Rosenfeld EA: Nontuberculous Mycobacterium Species. In: Principles and Practice of Pediatric Infectious Diseases, Long SS, Pickering LK, Prober CG (a cura di), Churchill Livingstone, 1998, p. 904.
13. Taha AM, Davidson PT, Bailey WC: Surgical treatment of atypical mycobacterial lymphadenits in children. Ped Infect Dis J 14, 664-7, 1985.
14. Margileth A: Management of nontuberculosis (atypical) mycobacterial infections in children and adolescents. Pediatr Infect Dis J 4, 119-21, 1975.
15. Kelly SC, Kelly RE Jr: Linfoadenopathy in children. Pediatr Clin North Am 45, 875- 888, 1998.
16. Wolinsky E: Mycobacterial lymphadenitis in children: a prospective study of 105 non tuberculous cases with long-term followup. Clin Infect Dis 20, 954-63, 1995.
17. Berger C, Pfyffer GE, Nadal G: Treatment of non-tuberculous mycobacterial lymphadenitis with clarithromycin plus rifabutin. J Pediatr 128, 383-6, 1996.
18. Young LS et al: Azythromycin for tratment of Mycobacterium avium intracellulare complex infection in patients with AIDS. Lancet 338, 1107-10, 1991.
31. Tessier MH, Amoric JC, Mechinaud F, Dubesset D, Litoux, Stalder JF: Clarithromycin for atypical mycobacterial lymphadenitis in non-immunocompromised children. Lancet 344, 8939-40, 1994.
2. Powell DA: Non tuberculous mycobacteria. In: Textbook of Pediatrics, Behrman RE, Kliegman RM, Arvin AM (a cura di), WB Saunders Co, 1996, p. 847.
3. American Academy of Pediatrics. Committee on Infectious Diseases: Micobatteri nontubercolari. In: Report of the Committee on Infectious Diseases (Red Book), ed. Italiana, 1997, pp. 348, 535.
4. Cross JT, Jacobs RF: Other Mycobacteria. In: Textbook of Pediatric Infectious Disease. Feigin RD, Cherry JD (a cura di), WB Saunders Co, 1998, p. 1239.
5. Margileth AM: Nontuberculous (Atypical) Mycobacterial Disease. In: Current Pediatric Therapy, Burg FD, Wald ER, Ingelfinger JR, Polin RA (a cura di), WB Saunders Co, 1996, p. 609.
6. Deriu GM, Tortoli E, Massei F, Caroli G: Un incontro col Mycobacterium malmoense. L’Igiene Moderna 103, 335-342, 1995.
7. Huebner RE, Schein MF, Cauthen GM: Usefulness of skin testing with mycobacterial antigens in children with cervical lymphadenopathy. Pediatr Infect Dis J 11, 450-55, 1992.
8. Del Beccaro MA, Mendelman PM, Nolan C: Diagnostic usefullness of mycobacterial skin test antigens in childhood lymphadenits. Pediatr Infect Dis J 8, 206-210, 1989.
9. Clark J, Magee GJ, Cant JA: Non-tuberculous mycobacterial lymphadenopathy. Arch Dis Child 72, 165-166, 1995.
10. Vecchi V, Burnelli R: Linfoadenopatie nell’infanzia: studio epidemiologico e approccio diagnostico-terapeutico. Edyt Symposia Pediatria e Neonatologia 1, 129-141, 1997.
11. Marseglia GL, Marone P: Le infezioni da micobatteri non tubercolari. In: Infettivologia Pediatrica, UTET, 1997, p. 55.
12. Chadwick GE, Rosenfeld EA: Nontuberculous Mycobacterium Species. In: Principles and Practice of Pediatric Infectious Diseases, Long SS, Pickering LK, Prober CG (a cura di), Churchill Livingstone, 1998, p. 904.
13. Taha AM, Davidson PT, Bailey WC: Surgical treatment of atypical mycobacterial lymphadenits in children. Ped Infect Dis J 14, 664-7, 1985.
14. Margileth A: Management of nontuberculosis (atypical) mycobacterial infections in children and adolescents. Pediatr Infect Dis J 4, 119-21, 1975.
15. Kelly SC, Kelly RE Jr: Linfoadenopathy in children. Pediatr Clin North Am 45, 875- 888, 1998.
16. Wolinsky E: Mycobacterial lymphadenitis in children: a prospective study of 105 non tuberculous cases with long-term followup. Clin Infect Dis 20, 954-63, 1995.
17. Berger C, Pfyffer GE, Nadal G: Treatment of non-tuberculous mycobacterial lymphadenitis with clarithromycin plus rifabutin. J Pediatr 128, 383-6, 1996.
18. Young LS et al: Azythromycin for tratment of Mycobacterium avium intracellulare complex infection in patients with AIDS. Lancet 338, 1107-10, 1991.
31. Tessier MH, Amoric JC, Mechinaud F, Dubesset D, Litoux, Stalder JF: Clarithromycin for atypical mycobacterial lymphadenitis in non-immunocompromised children. Lancet 344, 8939-40, 1994.