Caso contributivo
Due infezioni riemergenti in una bambina proveniente dall'estero
Two emerging infectious diseases in a foreign-born child
Daniele Le Serre1, Silvia
Virano3, Silvia Garazzino2, Michele Pinon3, Carlo Scolfaro2, Pier-Angelo Tovo 4
SUP>1Medico Frequentatore, 2Dirigente Medico, 3Medico Specializzando, 4Direttore,
SCDU Pediatria II, Divisione di Malattie Infettive, Ospedale Infantile Regina Margherita, Università di Torino
Aprile 2013
Abstract
Emerging infectious diseases may be present in foreign-born children. The case of a 5-year-old female, born in Ethiopia, who arrived in Italy one month before is reported. Screening investigations performed at our Centre documented a positive QuantiFERON-TB test and microscopic hematuria: further studies revealed diagnosis of pulmonary TB, in asymptomatic patient, and schistosoma infection. An efficacious antitubercular treatment, including moxifloxacin due to the isolation of isoniazid-resistant Mycobacterium tuberculosis, was administered for 7 ½ months and stopped early because of fluoroquinolone-induced tendinopathy. Afterwards, the child was treated with praziquantel. No signs of treatment failure or relapse were observed at the 3-month follow-up for both diseases.
In conclusion, diseases such as tuberculosis and schistosoma infection must always be considered in foreign-born children.
Contenuto riservato
Per leggere l'articolo è necessario effettuare il login.
Suggerite dall'AI
Classificazione MeSH
Bibliografia
1. G. Bona. Il bambino immigrato, Volume 1. Editeam Gruppo Editoriale 2003.
2. www.glnbi.org.
3. Cataldo F, Bonsignori I, Viviano E, Bona G. Il bambino immigrato e le vaccinazioni: quali strategie adottare? Conoscere per Crescere - Supplemento 2009, Editeam gruppo Editoriale 2009.
4. D’Auria A, Renzi S, Napoli PA, Franco E. Tuberculosis and immigration: criticality and possible remedial actions. Ig Sanita Pubbl 2011;67:793-804.
5. Istituto superiore di sanità. La tubercolosi in Italia. Rapporto 2000.
6. Panizon F. La tubercolosi ieri, oggi e domani: tra ricordi, epidemiologia e innovazione. Medico e Bambino 2011;30:581-582. http://www.medicoebambino.com/?id=1109_581.pdf.
7. Bartolozzi G. La tubercolosi (prima parte). Medico e Bambino pagine elettroniche 2004;7(1) http://www.medicoebambino.com/?id=OS0401_10.html
8. Treatment of Tuberculosis. American Thoracic Society, CDC, and Infectious Diseases Society of America. www.cdc.gov/mmwr
9. Seddon JA, Hesseling AC, Marais BJ, et al. Paediatric use of second-line anti-tuberculosis agents: a review. Tuberculosis (Edimb) 2012;92:9-17.
10. Bartolozzi G. La tubercolosi (seconda parte). Medico e Bambino pagine elettroniche 2004;7(2) http://www.medicoebambino.com/?id=OS0402_10.html
11. Al-Dabbagh M, Lapphra K, McGloin R, et al. Drug-resistant tuberculosis: pediatric guidelines. Pediatr Infect Dis J 2011;30:501-5.
12. Lalvani A. Diagnosing Tuberculosis Infection in the 21st century : new tools to tackle an old enemy. Chest 2007;131;1898-906.
13. Centers for Disease Control and Prevention. Updated Guidelines for Using Interferon Gamma Release Assays to Detect Mycobacterium tuberculosis Infection. MMWR, United States, 2010
14. Gray DJ, Ross AG, Li YS, McManus DP. Diagnosis and management of schistosomiasis. BMJ 2011;342:d2651.
15. Jauréguiberry S, Paris L, Caumes E. Acute schistosomiasis, a diagnostic and therapeutic challenge. Clin Microbiol Infect 2010;16:225-31.
16. Liu R, Dong HF, Guo Y, Zhao QP, Jiang MS. Efficacy of praziquantel and artemisinin derivatives for the treatment and prevention of human schistosomiasis: a systematic review and meta-analysis. Parasit Vectors 2011;4:201.
17. Gryseels B, Polman K, Clerinx J, Kestens L. Human schistosomiasis. Lancet 2006;368:1106-18.
18. http://www.dpd.cdc.gov/dpdx.
