Rivista di formazione e aggiornamento professionale del pediatra e del medico di base, fondata nel 1982. In collaborazione con l'Associazione Culturale Pediatri.
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Vitamina D: č indispensabile... ma non esageriamo!

Vitamin D is essential...
but do not exaggerate!

Elisa Maria Gabriella Marrella1, Sylvie Tagliati1, Sara Brachi1, Claudia Gelli1, Michela Giovannini1, Giuliana Turlą1, Cristina Malaventura
1Scuola di Specializzazione in Pediatria, Universitą di Ferrara
2Clinica Pediatrica, Arcispedale Sant’Anna, Ferrara

Ottobre 2013

Abstract
The article presents a case of severe hypercalcemia due to hypervitaminosis D in a 5-month-old infant. The child was fed with infant formula. He received 2 drops of 25-hydroxy vitamin D3/day since he was born. His clinical features showed growth retardation, anorexia and dehydration, axial hypotonia, psychomotor development retardat and closed anterior fontanel. Investigations showed low levels of parathormone, marked hypercalciuria, high levels of 25-OH vitamin D3 and nephrocalcinosis established by ultrasound evaluation. The infant was treated with parenteral hydration, oral prednisone and oral potassium citrate. The Vitamin D supplementation was stopped. Furthermore, the regular feeding milk was replaced with a new low-calcium and vitamin D-free one. This clinical case has to be taken as an example to discourage the routine use of vitamin D metabolites as prophylaxis of hypovitaminosis D.
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Parole chiave
Hypercalcemia Nephrocalcinosis Vitamin D
Suggerite dall'AI
Nefrocalcinosi Vitamin D supplementation
Classificazione MeSH
Polycyclic Compounds Fused-Ring Compounds Steroids Cholestanes Cholestenes Cholecalciferol
Physiological Phenomena Diet, Food, and Nutrition Food Dietary Supplements (33)
Pathological Conditions, Signs and Symptoms Signs and Symptoms Neurologic Manifestations Neuromuscular Manifestations Muscle Hypotonia (51)
Hormones, Hormone Substitutes, and Hormone Antagonists Hormones Peptide Hormones Parathyroid Hormone (6)
Polycyclic Compounds Fused-Ring Compounds Steroids Pregnanes Pregnadienes Pregnadienediols
Leggi anche
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Fisiopatologia della vitamina D (Prima parte)
G. Bartolozzi · 2007
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EL Seminari degli specializzandi
Quando dare la vitamina D
S. Bassanese, S Norbedo · 2004
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A. Agrusti, S. Contorno, I. Bruno, G. Gortani, E. · 2020
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