Caso contributivo
Entero-artrite reattiva da Clostridium difficile:
relazione casuale o causale? Descrizione di un caso clinico
Clostridium difficile reactive entero-arthritis in a child: a case report
Fabrizio Pugliese1, Andrea Zucchini2, Paolo Ricciardelli2, Michela Cappella1, Federico Marchetti1
1UOC di Pediatria e Neonatologia, Ospedale di Ravenna, AUSL della Romagna
2Pediatria di Faenza
Maggio 2015
Abstract
In adults reactive arthritis (ReA) following Clostridium diffıcile-enterocolitis has been documented. In children only five case of C. diffıcile-associated ReA has been reported. The paper describes a case of ReA in a six-year-old boy treated for upper respiratory infection with a ten-day course of amoxicillin-clavulanic acid. The child developed polyarthritis after three weeks of diarrhoea with positive stool cultures for C. diffıcile. Arthritis is asymmetrical with a self-limiting course with nonsteroidal anti-inflammatory and metronidazole treatment.
Contenuto riservato
Per leggere l'articolo è necessario effettuare il login.
Parole chiave
Suggerite dall'AI
Bibliografia
Carter JD. Reactive arthritis: defined etiologies, emerging pathophysiology, and unresolved treatment. Infect Dis Clin North Am 2006;20(4):827-47.
Bartlett JG. Historical Perspectives on Studies of Clostridium difficile and C. difficile infection. Clin Infect Dis 2008;46(Supplement 1):S4-S11.
Wiström J, Norrby SR, Myhre EB, et al. Frequency of antibiotic-associated diarrhoea in 2462 antibiotic-treated hospitalized patients: a prospective study. J Antimicrob Chemother 2001;47:43-50.
Sammons JS, Toltzis P, Zaoutis TE. Clostridium difficile infection in children. JAMA Pediatr 2013;167(6):567-73.
Birnbaum J, Bartlett JG, Gelber AC. Clostridium difficile: an under recognized cause of reactive arthritis? Clin Rheumatol 2008;27:253-5.
Jacobs A, Barnard K, Fishel R, Gradon JD. Extracolonic manifestations of Clostridium difficile infections. Presentation of 2 cases and review of the literature. Medicine (Baltimore) 2001;80(2):88-101.
Cron RQ, Gordon PV. Reactive arthritis to Clostridium difficile in a child. West J Med 1997;166:419-21.
Löffler HA, Pron B, Mouy R, Wulffraat NM, Prieur AM. Clostridium difficile-associated reactive arthritis in two children. Joint Bone Spine 2004;71:60-2.
Durand CL, Miller PF. Severe Clostridium difficile colitis and reactive arthritis in a ten-year-old child. Pediatr Infect Dis J 2009;28:750-1.
Dacheux C, Pruvost I, Herbaux B, Nectoux E. Clostridium difficile reactive arthritis in a 7-year-old child. Arch Pediatr 2012;19(6):607-11.
Puttermann CH, Rubinow A. Reactive arthritis associated with Clostridium diffıcile pseudomembranous colitis. Sem Arthritis Rheum 1993;22:420-6.
Schutze GE, Willoughby RE; Committee on Infectious Diseases, American Academy of Pediatrics. Clostridium difficile infection in infants and children. Pediatrics 2013;131(1):196-200.
Ananthakrishnan AN, Issa M, Binion DG. Clostridium difficile and inflammatory bowel disease. Gastroenterol Clin North Am 2009;38(4):711-28.