Prolactinoma is a rare benign neoplasia in paediatric age that mostly affects female adolescents. In most cases the adopted therapy is pharmacological with dopamine-agonists and the first choice is cabergoline that shows a good safe and efficacious profile. The article presents the case of a 15-year-old girl presenting with secondary amenorrhoea, migraine and other less specific accompanying symptoms and whose MR allowed prolactin secreting microadenoma to be diagnosed and promptly treated with cabergoline.