The paper describes the clinical case of a ten-year-old boy with Tourette’s syndrome, initially classified as PANDAS. The persistence, the complexity of the symptoms and the comorbidity with obsessive-compulsive disorders (OCD) have framed the case as Tourette syndrome and OCD. Treatment with cognitive behavioural therapy and aripiprazole gave a good clinical response, with partial regression of the symptoms. In the light of clinical improvement, a good prognosis is expected in the long term.