I Poster degli specializzandi
Dolore, edema e febbre: riconoscere precocemente la trombosi settica da MSSA nell’adolescente
Pain, oedema and fever: early recognition of mssa septic thrombosis in adolescents
Giovanna Centonze1, Luca Di Bella1, Antonia Cantavenera1, Laura Napoli1, Enrico Catania1, Claudia Colomba2
1Scuola di Specializzazione in Pediatria, Universtà di Palermo
2UOC di Malattie Infettive Pediatriche, PO “G. Di Cristina”, ARNAS CIVICO, Palermo
Luglio 2026 | DOI: 10.53126/MEBXXIXSU188
Abstract
The paper reports the case of a 15-year-old boy who presented to the Emergency Room with oedema and erythema in the right perimalleolar region. Following worsening of symptoms, high fever and dyspnoea, further investigations (colour Doppler ultrasound and chest CT) revealed a right popliteal deep vein thrombosis (DVT) complicated by multiple septic pulmonary emboli. The patient was admitted in poor general condition with significantly elevated inflammatory markers. Microbiological cultures (BAL, blood cultures and skin swab) tested positive for methicillin-susceptible Staphylococcus aureus (MSSA). The management involved a dual strategy combining targeted antibiotic therapy (adjusted with daptomycin and cefazolin) and anticoagulation with low-molecular-weight heparin (LMWH), resulting in progressive clinical improvement and discharge after about one month. The case underscores the crucial need for early recognition of DVT and septic pulmonary embolism as rare but severe complications of community-acquired MSSA sepsis, even in immunocompetent paediatric patients.
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