Hemophagocytic lymphohistiocytosis (HLH)

Parvovirus: un solo virus per tante malattie

Burlo F, Colussi L, Zanchi C, Bloise S, Marchetti F, Cozzi G.

2025/4 — pag. 229-234 — DOI

Parvovirus B19 causes a wide range of clinical manifestations, with a peak incidence between 5 and 15 years of age. The spectrum of clinical manifestations associated with Parvovirus infection varies depending on the host's age, haematological status...

Leishmania e linfoistiocitosi emofagocitica (HLH)

Bratta A, Arcuri L, Micalizzi C

2025/2 — pag. 51-52 — DOI

Haemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening hyperinflammatory syndrome. The paper reports the case of a 5-month-old infant hospitalised with persistent fever, splenomegaly and significant inflammatory activation. After an ini...

Febbre e citopenia nel neonato: pensa anche all'HLH (e dosa la ferritina!)

Operti M

2024/4 — pag. 80-81 — DOI

The author describes the case of a newborn with fever and cytopenia, eventually diagnosed as familial hemophagocytic lymphohistiocytosis....

Covid-19 e risposta immune

S. Volpi, S. Naviglio, A. Tommasini

2020/4 — pag. 223-231

Covid-19 outbreak is about to reach the peak of infected people in Italy. Huge amount of data is being published on this epidemic in all medical journals, with especial concern on severe cases. Unfortunately, most reports are just descriptive and onl...

Linfoistiocitosi emofagocitica, tubercolosi e immunodeficienza primitiva

L. Lodi, R. Cupone

2020/1 — pag. 20-20

L’EBV che non mi aspetto: MASe ci penso...!

A. Di Mascio, C. Redice, S. Pusceddu, V. Camelli, F. Marchetti

2016/10 — pag. 637-640

The paper reports the case of a 14-year-old boy who presented to our attention because for three days he had fever, laterocervical lymphadenopathy with limited movements of the neck and cytopoenia. The clinical diagnostic process led to the diagnos...

Cosa deve sapere il pediatra della linfoistiocitosi emofagocitica attraverso i casi degli specializzandi

S. Lega, F. Dell’Acqua, M. Minute, F. Vendemini, C. Cattelani

2015/7 — pag. 431-441

Hemophagocytic lymphohistiocytosis (HLH) is a potentially life-threatening syndrome caused by severe hypercytokinemia due to a highly stimulated but ineffective immune response. HLH is not a disease by its own but is rather a common final consequen...

Una febbre alta e persistente con epatosplenomegalia e citopenia

L. de Seta, M.S. Sabatino, F. de Seta, P. Siani

2015/7 — pag. 431-441

The case described is that of an 11-year-old child presenting with high fever, pharyngotonsillar exudate, submandibular strangles and hepatosplenomegaly. The elevated number of VCA IgM antibodies led to a diagnosis of infectious mononucleosis. The ...

Linfoistiocitosi emofagocitica: una complicanza che non ti aspetti

A. Grigoli, P. Farruggia, G. Bruno, S. Cannella, D. Caselli, P. D’Angelo, D. Russo, A. Trizzino, S. Tropia, O Ziino, M. Aricò

2014/10

Haemophagocytic lymphohistiocytosis (HLH) is a clinical syndrome caused by hypersecretion of cytokines secondary to temporary or persistent failure of the immune system. The sporadic form usually occurs in the first months of life as a result of an i...