Rivista di formazione e aggiornamento professionale del pediatra e del medico di base, fondata nel 1982. In collaborazione con l'Associazione Culturale Pediatri.
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Analisi retrospettiva della malattia di Kawasaki nel Nord-Est d’Italia: è il momento di una revisione dei criteri diagnostici?

KAWASAKI DISEASE: A RETROSPECTIVE ANALYSIS OF 58 CASES

PAOLO PECILE1, LOREDANA LEPORE2, CARLA PITTINI1, SERGIO FACCHIN2

1Clinica Pediatrica, Policlinico Universitario, DPMSC, Udine
2Clinica Pediatrica, IRCCS “Burlo Garofolo”, Trieste

Gennaio 2003 - pagg. 43 -46

Abstract
The incidence of Kawasaki disease (KD) varies across countries, and open issues are mainly related to etiology and diagnosis of atypical cases. A multicentric collaborative study was carried out of all cases of KD admitted in paediatric wards of the Friuli Venezia- Giulia Region, Italy, over the period 1990-2001. Out of 58 cases, 82% were younger than 5 years (incidence 9,5/100.000 under 5 years). In 15 cases (26%) the clinical presentation was atypical, lacking one or more of the diagnostic criteria, but diagnosis was made on the basis of the unique combination of clinical and laboratory features. Atypical cases are more likely to occur at younger ages (2.1 versus 3.9 years at onset). ECG changes were found in 25% of cases, but no cases of coronary aneurisms were observed. High-dose immunoglobulins were given soon, after a mean period of 6.5 days from the onset. Since at least 1 in 4 cases of KD has an atypical presentation, diagnostic criteria could be revised to allow earlier diagnosis of atypical cases.
Parole chiave
atypical presentation immunoglobuline Immunoglobulins Kawasaki disease Malattia di Kawasaki presentazione atipica
Suggerite dall'AI
Diagnostic criteria Vasculite Vasculitis
Classificazione MeSH
Cardiovascular Diseases Heart Diseases Myocardial Ischemia Coronary Disease Coronary Aneurysm (24)
Diagnosis Diagnostic Techniques and Procedures Diagnostic Techniques, Cardiovascular Heart Function Tests Electrocardiography (44)
Amino Acids, Peptides, and Proteins Proteins Blood Proteins Immunoproteins Immunoglobulins Antibodies
Cardiovascular Diseases Vascular Diseases Vasculitis Mucocutaneous Lymph Node Syndrome (126)
Cardiovascular Diseases Vascular Diseases Vasculitis (47)
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