Rivista di formazione e aggiornamento professionale del pediatra e del medico di base, fondata nel 1982. In collaborazione con l'Associazione Culturale Pediatri.
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Test per il Covid-19: un po’ di chiarezza per evitare errori

Covid-19 tests: a little clarity to avoid mistakes

Roberto Buzzetti

Epidemiologo freelance, Bergamo

Maggio 2020 - pagg. 305 -306

Abstract
There is confusion on the role of the available Covid-19 tests. While serological tests give information on the passage of the virus (did I get infected?), the swab describes the current situation (am I infected?). The information on the occurred contact with the virus helps to estimate the likelihood to be infected and to prevent the further spread of the disease. Particular attention is to be paid to the specificity of a serological test that, if it is not sufficiently close to 100%, can produce a worrying number of false positive subjects. Therefore, this type of tests is more useful to monitor the prevalence of the infection in the community rather than to give a misleading immunity “license” to individuals.
Parole chiave
Coronavirus Covid-19 tests immunità Immunity Serological tests Test COVID-19 test sierologici
Classificazione MeSH
Environment and Public Health Public Health Public Health Practice Communicable Disease Control Contact Tracing (7)
Diagnosis Diagnostic Techniques and Procedures Clinical Laboratory Techniques COVID-19 Testing (4)
Diagnosis Diagnostic Errors False Positive Reactions (2)
Amino Acids, Peptides, and Proteins Proteins Blood Proteins Immunoproteins Immunoglobulins Antibodies
Amino Acids, Peptides, and Proteins Proteins Blood Proteins Immunoproteins Immunoglobulins Antibodies
Health Care Quality, Access, and Evaluation Quality of Health Care Health Care Evaluation Mechanisms Epidemiologic Research Design Sensitivity and Specificity (35)
Diagnosis Diagnostic Techniques and Procedures Clinical Laboratory Techniques Immunologic Tests Serologic Tests (31)
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Bibliografia
di riferimento • AMCLI (Associazione Microbiologi Clinici Italiani). SARS-CoV-2: la diagnosi sierologica. 31 marzo 2020:1-4. • Grassly NC, Pons-Salort M, Parker EPK, et al. Report 16: role of testing in COVID-19 control. Imperial College London, April 23, 2020:1-13. • Lou B, Li T, Zheng S, et al. Serology characteristics of SARS-CoV-2 infection since the exposure and post symptoms onset. MedRxiv March 27, 2020 [Epub ahead of print].

Corrispondenza: robuzze@gmail.com