Neonatologia
La listeriosi neonatale e materno-fetale
Neonaltal and maternal-fetal listeriosis
Davide Scarponi1, Marco Ranalli1, Luca Bedetti2*, Francesca Miselli2, Katia Rossi2, Lorenzo Iughetti3, Licia Lugli2, Alberto Berardi2
1Scuola di Specializzazione in Pediatria, 2Terapia Intensiva Neonatale, 3UO di Pediatria, AOU Policlinico di Modena
*PhD Programme in Clinical and Experimental Medicine, Università di Modena e Reggio Emilia
Marzo 2023 - pagg. 177 -182 | DOI: 10.53126/MEB42177
Abstract
Listeriosis is a foodborne condition associated with the ingestion of food contaminated by Listeria monocytogenes that can cause serious health consequences in neonates and pregnant women. In these groups the incidence of the disease is higher due to the relative immunocompromised state and the particular Listeria monocytogenes tropism for the placenta. The paediatrician and the neonatologist must therefore be able to recognize the signs and symptoms of the disease promptly so as to set up an adequate treatment according to the most recent international guidelines. This article provides epidemiological data and describes the pathophysiology and clinical manifestations of maternal-foetal and neonatal listeriosis, as well as the therapeutic indications according to very recent recommendations.
Riassunto
La listeriosi è una patologia di origine alimentare causata dall’ingestione di cibo contaminato da Listeria monocytogenes (LM) che può causare serie conseguenze per la salute di neonati e donne in gravidanza. In questi gruppi di popolazione l’incidenza della patologia è maggiore a causa dello stato di relativa immunocompromissione e al particolare tropismo che LM possiede per la placenta. Il pediatria e il neonatologo devono pertanto essere abili a identificare precocemente i segni e sintomi della patologia per impostare un trattamento adeguato sulla base delle più recenti linee guida internazionali. L’articolo fornisce dati epidemiologici, descrive la fisiopatologia e le manifestazioni cliniche della listeriosi materno-fetale e neonatale, così come le indicazioni sulle terapie basate sulle più aggiornate linee guida.
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Classificazione MeSH
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Corrispondenza: alberto.berardi@unimore.it