Bile Duct Diseases

BRIC o PFIC?

Gibellato E, Lauriola RS, D'Antiga L

2025/10 — pag. 257-259 — DOI

A 9-year-old boy of Moldovan origin presented to the Emergency Room with jaundice and pruritus persisting for two months. His medical history revealed recurrent, self-limiting episodes and a recent hospitalization in Moldova for hyperbilirubinemia tr...

Parvovirus: un solo virus per tante malattie

Burlo F, Colussi L, Zanchi C, Bloise S, Marchetti F, Cozzi G.

2025/4 — pag. 229-234 — DOI

Parvovirus B19 causes a wide range of clinical manifestations, with a peak incidence between 5 and 15 years of age. The spectrum of clinical manifestations associated with Parvovirus infection varies depending on the host's age, haematological status...

Anche il fegato ha i suoi binomi

Maggiore G.

2025/3 — pag. 183-184 — DOI

The paper describes the case of a 20-month-old girl hospitalized for acute liver failure, later diagnosed with progressive familial intrahepatic cholestasis (PFIC). Jaundice is often a fundamental clinical sign that is frequently overlooked, not only...

Rivista sfogliabile on line

2024/6

Colestasi neonatale e fibrosi cistica

Maggiore G.

2024/6 — pag. 116-117 — DOI

The diagnosis of cystic fibrosis was eventually made in a one-month-old infant with cholestasis. The newborn screening for cystic fibrosis had been falsely negative....

L’ittero in un lattante

Moras M, Tanzi G, Melli P, Cogo P.

2024/5 — pag. 329-331 — DOI

The diagnosis of biliary atresia was ultimately made in an infant who still presented with jaundice after his first month of life and had previously been misdiagnosed with breast milk jaundice. The authors underline that biliary atresia should always...

Le colelitiasi a origine ematologica

Fantasia M, Faraguna MC, Ferrari GM, Corti P.

2024/3 — pag. 187 — DOI

A 7-year-old girl presenting with acute abdominal pain due to gallstones was eventually diagnosed with spherocytosis....

Un’insolita ipertensione polmonare

Todero S, Hasan T, Ragni L, Donti A

2023/1 — pag. 13-13 — DOI

The Authors describe the case of a newborn presenting with severe pulmonary hypertension due to the hypoplasia of the pulmonary arteries and finally diagnosed with Alagille syndrome. The typical vertebral anomalies and hyperbilirubinaemia were also p...

Una colestasi che ritorna

Medici F

2022/8 — pag. 527-530 — DOI

The case of a 13-month-old girl with recurrent cholestasis finally diagnosed with BRIC (Benign Recurrent Intrahepatic Cholestasis) is described. The clinical, therapeutic and prognostic implications of BRIC are also discussed....

Una colestasi che ritorna

Medici F

2022/8 — pag. 169-170 — DOI

The case of a 13-month-old girl with recurrent cholestasis finally diagnosed with BRIC (Benign Recurrent Intrahepatic Cholestasis) is described. The clinical, therapeutic and prognostic implications of BRIC are also discussed....

Secondo i miei “calcoli”... non è una gastrite

Arnaboldi S, Quattrocchi G, Ferrari GM, Corti P

2022/6 — pag. 129-130 — DOI

The case of an 11-year-old girl affected by hereditary spherocytosis admitted to hospital for abdominal pain is described. The diagnosis of cholelithiasis was eventually made....

Diagnosi delle colestasi neonatali e infantili

Maggiore G, Della Corte C.

2022/4 — pag. 244-248 — DOI

Neonatal and infantile cholestasis (NIC) may represent the onset of a surgically correctable disease and of a genetic or metabolic disorder worthy of medical treatment. Timely recognition of NIC and identification of the underlying aetiology are para...

Quando il fegato parla, ascolta (anche) l’intestino

Calia M, Lattuada M, Lebiu M

2022/4 — pag. 95-95 — DOI

The case of a 16-year-old adolescent with abdominal pain finally diagnosed with sclerosing cholangitis and inflammatory bowel disease is described. The possible involvement of the liver in IBD is discussed....

Epatologia e gastroenterologia

Maggiore G, Bramuzzo M

2021/26 — pag. 5 — DOI

Gialla fuori... e gialla dentro

A.G. Grasso

2020/9 — pag. 236-236 — DOI

Un ittero neonatale colestatico: semaforo verde!

F.M. Risso

2020/7 — pag. 461-463 — DOI

Un prolasso nell’ambulatorio... “sbagliato”

A. Daidone

2020/7 — pag. 461-463 — DOI

La riapertura delle scuole e il lavoro del pediatra Covid-19: perché è meglio dimenticarsi dell’idrossiclorochina Allattamento al seno e diagnosi di atresia delle vie biliari Le possibili applicazioni della telemedicina

2020/7 — pag. 420-423 — DOI

Non di solo Covid uccide il Covid… “Deve avere qualcosa” Atresia biliare: guai sbagliare È ora di cambiare Anoressia nervosa, osteoporosi ed estrogenoterapia Il circo dei… probiotici

2020/7 — pag. 417-418 — DOI

Non era una colangite infettiva

M. Mainetti, F. Marchetti

2020/5 — pag. 317-318

A picture of the onset of “hepatocolangitis” especially if with dilatation of the biliary tract must necessarily make one think of primary sclerosing cholangitis (PSC). The suspicion of PSC must always make one think of concomitant chronic inflammato...

Un ittero colestatico neonatale: la sindrome di Alagille

E. Rizzello, J. Bua, S. Nider

2019/9 — pag. 226-227

Ematemesi rivelatrice

R. Pillon

2019/8 — pag. 207-207

Il neonato a colori: le sfumature di grigio

G. Corsello, M. Schierz

2019/7 — pag. 455-456

Lattanti e trapianti

F. Fusco

2018/10 — pag. 662-663

Rettocolite ulcerosa e colangite autoimmune

S. Carbogno

2018/10

Gastroenterologia pediatrica: quattro casi per quattro messaggi

M. Bramuzzo

2018/5 — pag. 315-318

The present paper shortly describes four cases and gives some useful remarks to paediatricians about four gastroenterological conditions: sclerosing cholangitis, intestinal polyps, isolate rectal ulcer and early onset inflammatory bowel disease....

Kawasaki facile e difficile

E. Benelli, S. Carbogno, N.S. Carucci, M. Gori, E. Marrani, M. Melis, M.C. Pellegrin

2017/3 — pag. 155-162

Kawasaki disease (KD) is a systemic vasculitis that typically affects children of 2-5 years of age and whose diagnosis and treatment are usually easy, as described in the first case report. Anyway, in spite of adequate therapy, 10-15% of patients d...

MAS in WAS? (una Wiskott-Aldrich non convenzionale)

S. Amoroso

2016/10

Profilassi del sanguinamento da deficit di vitamina K: finalmente la luce?

G. Maggiore, S. Demarini

2016/8 — pag. 483-485

Nuove evidenze sulla profilassi neonatale con vitamina K

C. Lama, S. Pusceddu, P. Gallo, F. Marchetti

2016/8 — pag. 531-533

Nuove evidenze sulla profilassi neonatale con vitamina K

C. Lama, S. Pusceddu, P. Gallo, F. Marchetti

2016/8

Transaminasi che non passano: tutto quello che dobbiamo sapere

S. Nastasio

2016/7 — pag. 459-460

Calcolosi biliare: non solo per adulti...

G. Rossi, F. Cirillo, M. Sciveres, S. Riva, C. Ricotta, M. Spada, G. Maggiore

2015/8 — pag. 495-503

In recent years cholelithiasis has been on the rise among infants and children, partly because of improved diagnostic modalities, but also because of an increased awareness of emerging comorbidities, such as childhood obesity, and other associated ...

Epatite acuta con colestasi da Parvovirus B19

S. Perrini, b. Guidi, P. Torelli, A. Forte

2015/2 — pag. 119-121

Few cases of acute hepatitis due to Parvovirus B19 are reported in the literature. The paper describes a case of acute cholestatic hepatitis due to Parvovirus B19 infection. Diagnosis was based on a positive serologic test (IgM) and on molecular dete...

Due colestasi a confronto

M. Massaro, E. Benelli, M.C. Pellegrin

2014/9

Una colestasi... ricorrente

F. Barbieri

2014/2

La sindrome di Alagille

S. Nastasio, M. Sciveres, S. Ghione, G. Marsalli, F. Cirillo, S. Riva, G. Maggiore

2013/10 — pag. 635-642

Alagille syndrome (ALGS, OMIM 118450) is a multisystem disorder due to defects in components of the Notch signalling pathway. Its main clinical and pathological features are chronic cholestasis due to paucity of intrahepatic bile ducts, peripheral ...

Le dilatazioni cistiche delle vie biliari

M. Sciveres, F. Cirillo, S. Nastasio, G. Maggiore

2013/5 — pag. 295-301

Cystic disease of the biliary tree is a rare and heterogeneous medical condition that may be diagnosed during intrauterine life or can become symptomatic with cholestatic jaundice or acute recurrent pancreatitis before adulthood. The etiology remai...

BRIC e PFIC 2 un continuum tra genotipo e fenotipo?

S. Ghione, M.E. Di Cicco, F. Moscuzza, G. Rossi, M. Segreto, G. Marsalli, G. Maggiore

2013/5

Dove va (o vorrebbe andare) l’epatologia pediatrica?

G. Maggiore

2012/8 — pag. 483-485

Un caso di febbre persistente

R. Puxeddu, A.P. Pinna, V. Pisano, A. Doneddu, S. Marras, A.M. Nurchi

2012/8

Ittero in un lattante: quando l’assassino è proprio il maggiordomo

M. Bensa, E. Gubellini, M. Bramuzzo

2010/8 — pag. 525-526

L’epatopatia della malattia celiaca: uno spettrodi lesioni con una comune patogenesi?

S. Caprai, G. Maggiore

2010/6 — pag. 383-386

A wide spectrum of liver injuries in children and adults may be related to celiac disease (CD) and in particular: 1) a mild parenchymal damage characterized by absence of clinical sign or symptom of a chronic liver disease and by non-specific histo...

L’esplorazione bioumorale del fegato: il bilancio epatico

G. Maggiore

2009/10 — pag. 649-653

Liver function tests are a simple way to explore liver function and are a helpful tool to the clinician to confirm the clinical suspect of liver disease. Practically, evaluation of liver function includes determination of total and conjugated bilir...

Politiche sanitarie e salute infantile in Italia

L. Perletti

2009/9 — pag. 584-587

The organizational models of the supra-regional centres for rare diseases in some European countries are compared by reporting the cases of biliary atresia and cochlear implants in children. Once again Italy departs from Europe; the causes are exam...

Rifiuto del cibo: saper distinguere tra “fischi e fiaschi”. Invecchiare con la “Kasai”. Verso nuovi vaccini: è la volta del CMV. “Avena libre”. Antiepilettici in gravidanza e sviluppo cognitivo del bambino: attenzione al valproato!

2009/5 — pag. 285-286

A volte... ritornano. Una rettocolite "difficile".

2009/4 — pag. 257-258

Atresia delle vie biliari: quali insidie per il pediatra?

R. Iorio, A.M. Salzano, F. Cirillo, G. Vallone

2009/4 — pag. 224-231

Biliary atresia (BA) is the most common pediatric cause of cirrhosis, end-stage liver disease and indication for liver transplantation. The clinical presentation is characterized by jaundice with yellow or dark urine and pale stools, which eventually...

Colestasi neonatale: la grande simulatrice

M. Tufano, F. Cirillo, G. Ranucci, R. Vecchione, A. Sonzogni, D. Alberti, R. Iorio

2008/8 — pag. 527-529

Early detection and accurate diagnosis of cholestatic jaundice (CJ) are important for successful treatment and favourable prognosis but the rapid and effective recognition of the causes of cholestasis in infants is still challenging also for paed...

Colestasi neonatale: la grande simulatrice

M. Tufano, F. Cirillo, G. Ranucci, R. Vecchione, A. Sonzogni, D. Alberti, R. Iorio

2008/8

Emanuela: è tre il numero perfetto

Giuseppe Maggiore

2008/5 — pag. 322

Atresia biliare: non è mai troppo prestoStipsi severa nei bambini: non serve lo psicologoEstremi mali, estremi rimedi: chirurgia bariatrica per l'obesità grave dei bambini?Vaccino anti-Rotavirus umano attenuato: efficace anche "al di là dal mare"Neonati e “lattantini”: meglio distesi che seduti

2008/5 — pag. 283-284

Un’ipertransaminasemia urso-dipendente

G. Ranucci, F. Cirillo, L. D’Antiga, M. Tufano, M. D’Ambrosi,G. Giordano, R. Iorio

2008/3 — pag. 193-194

We present a case of a 6 year-old boy with chronic hypertransaminasemia referred to our observation at the age of 17 months, with ALT levels of 2,147 IU/L without signs of cholestasis. Main causes of hypertransaminasemia were excluded and liver b...

La storia vera, ma troppo lunga, di un lattante con ittero

V. Rametta, L. Zancan

2006/6 — pag. 385-386

Un caso di sindrome di Alagille

A. Borrelli, M. Teresa Carbone, A. Correra

2005/6

Un caso di sindrome di Alagille

A. Borrelli, Mt. Carbone, A. Correra

2005/6 — pag. 398-398

Il deficit di alfa1-antitripsina in età pediatrica

L. Giglio, I. Berti, C. Trevisiol

2003/3 — pag. 155-161

Alpha 1-antitrypsin deficiency (AATD) is an autosomal recessive disease, with more than 70 genetic variants, and a frequency which varies from 1:1000 to 1:5000, depending on genetic epidemiology and screening methods. The AATD involves primarily th...

Ittero tardivo e atresia delle vie biliariTra il dire e il fare: ITra il dire e il fare: IIRisposte fisiologiche a fisiologici bisogni

2003/3 — pag. 149-151

Colestasi nella mononucleosi infettiva da virus di Epstein-Barr

F. Massei, G. Palla, C. Ughi, et al.

2002/5 — pag. 308-310

Although biochemical evidence of liver damage is frequent in children with EBV infectious mononucleosis, signs or symptoms related to an impaired bile flow as jaundice or pruritus are rare. The Authors report three cases observed in a two-year peri...

Il trapianto epatico in età pediatrica: il punto attuale di un Centro italiano

G. Torre, M. Spada, S. Riva, et al.

2002/5 — pag. 302-310

The Authors report their experience on liver transplantation in children at the Pediatric Liver Transplantation Program, Ospedali Riuniti of Bergamo. Over a five year period 156 transplantations have been performed in 141 children (15 children requ...

Ittero colestatico in un bambino di un meseUn caso clinico personale di 10 anni fa

G. Bartolozzi

2002/3

Epatiti autoimmuni attorno all’anno 2000

I. Giuseppin, S. Martelossi, L. Lepore, G. Torre, I. Bruno,A. Ventura

2001/8 — pag. 499-508

Diagnosis of autoimmune hepatitis (AH) is based on: exclusion of viral genetic or tossic etiology, presence of non-organ-specific antibodies (SMA, ANA or LKM1); increased G immunoglobulin, typical histological features; response to immunosuppressiv...

Un prurito implacabile

I. Crupi

2001/3 — pag. 186-189

Colangite autoimmune in rettocolite ulcerosa: trattamento con acido ursodesossicolico

S. Martelossi, G. Torre

1999/7 — pag. 403-404

Il trattamento dell’acalasia dello sfintere interno conla tossina botulinica

A. Messineo

1999/3 — pag. 149

La diagnosi di ittero colestatico nel neonato

G. Maggiore, S. Caprai

1999/3 — pag. 157-161

The incidence of cholestatic jaundice in newborn babies is 1/2500 live births. Biliary atresia is the most frequent single cause of neonatal cholestasis, its frequency is 1/10.000 live births. The prognosis is strictly related to early surgical tre...

Artrite reumatoide: un grande passo avantiOtiti e virusFumo e appendiciteGeneral practitioner inglesi alla scoperta della celiachiaAtresia delle vie biliari e papillomavirusStatura e stagione di nascitaBronchioliteNascita e sviluppo dell’atopiaVaccino anti-HB per i non responder

1999/2 — pag. 77-78

L’atresia delle vie biliari

D. Baronciani

1998/3 — pag. 189-190

Celiachia e cirrosi biliare primitiva: una associazione non casualeVirus dell’epatite G: spettatore innocenteEpatite A su epatite C: un rischio da prevenireCeliachia trasmessa da trapianto di midolloMarijuana per il singhiozzo intrattabileDieta mediterranea: “il paradosso albanese”IgG endovena ad alte dosi e malattie autoimmuniSardegna e diabete: di generazione in generazioneSono veri ancor oggi, nel 1998, i timori per l’associazione sindrome di Reye/salicilati?Fumo in gravidanza: conseguenze sul prodotto del concepimento

1998/2 — pag. 79-80

Fegato a ultrasuoni

G. Maggiore, M. Massimetti

1998/1 — pag. 17-22

Over the past two decades ultrasonography (US) have emerged as the principal imaging method for diagnostic examination of the liver and biliary tree. US is relatively not expensive and safe: the single major disadvantage is its dependence upon a...