Hematopoietic Stem Cell Transplantation

Occhio all'emocromo... prima che sia tardi

Di Noto F, Lo Meo F, Marra G, Dimartino G, Gilotta C, Genduso M, Ferraro T, Allegra M, Guarina A, Cardella F, Corsello G

2025/7 — pag. 190-191 — DOI

A 5-year-old boy, presented with hematemesis, diffuse petechiae, epistaxis, respiratory distress and severe pancytopenia. After poor response to immunoglobulin and steroid therapy, bone marrow evaluation revealed trilineage cytopenia. The combination...

Una strana pancitopenia: dalla gestione in urgenza alla diagnosi genetica

Di Filippo M, Rossoni L, Nebiolo M, Fioredda F, Carrato V, Pirlo D

2024/10 — pag. 201-206 — DOI

Wiskott-Aldrich syndrome (WAS) is a rare X-linked genetic disorder caused by a mutation in the WAS gene that codes for the WASp protein, which is involved in the functioning of the cytoskeleton of non-erythroid haematopoietic cells. This mutation lea...

Febbre e citopenia nel neonato: pensa anche all'HLH (e dosa la ferritina!)

Operti M

2024/4 — pag. 80-81 — DOI

The author describes the case of a newborn with fever and cytopenia, eventually diagnosed as familial hemophagocytic lymphohistiocytosis....

Guardare oltre il tumore: le cancer-predisposing syndrome in età pediatrica

Bettini LR, Lauriola RS, Vendemini F, Coliva T, Biondi A, Cazzaniga G.

2023/4 — pag. 237-241 — DOI

About 10% of children with cancer carry a pathogenic mutation in genes predisposing to tumourigenesis. These mutations are being identified more and more frequently thanks to the use of next-generation sequencing techniques in the diagnostic work-up ...

Il ruolo del microbiota intestinale nella modulazione immunitaria

D. Leardini, E. Muratore, D. Zama, A. Prete, A. Pession, R. Masetti

2020/6 — pag. 130-136 — DOI

The intestinal microbiota plays a crucial role in numerous physiological and pathological processes of the developmental age. The development of new investigation methods, such as next generation sequencing, has allowed a more precise characterizatio...

Troppo stanca troppo presto: la leucemia mielomonocitica giovanile

S. Contorno

2019/4 — pag. 95-95

La gestione condivisa ospedale-territorio del bambino con malattia drepanocitica

P. Samperi, R. Colombatti, E. Cannata, L. Sainati, G. Russo

2017/10 — pag. 629-635

Sickle cell disease is a hereditary autosomal disease of haemoglobin characterized by chronic haemolytic anaemia, vaso-occlusive painful crisis, organ damage and increased susceptibility to infections. In recent years, the number of patients with s...

Leucemia linfoblastica acuta del bambino: al bivio tra successi e interrogativi

A. Biondi

2017/7 — pag. 415

La linfopenia nel bambino

C. Dallavilla, R. Badolato

2015/4 — pag. 239-246

Isolated lymphopoenia is a common finding in children evaluation. Usually, lymphopoenia is observed in children with infectious or autoimmune diseases, with nutritional disorders or under treatment with immunosuppressive drugs. However, persistence...

Valutazione della qualità della vita nei pazienti talassemici pediatrici post-trapianto

M. Ligas, M. Balzarini, F. Danjou, M.G. Orofino

2014/9

Aplasie midollari acquisite in età pediatrica: raccomandazioni diagnostico-terapeutiche

Gruppo di Lavoro “Insufficienze Midollari” dell’AIEOP

2014/6 — pag. 383-389

Acquired Aplastic Anaemia (AA) is a rare heterogeneous disease characterized by pancytopoenia and hypoplastic bone marrow. The incidence is 2-3 millions per year (all age groups) in Europe, but is higher in East Asia. The pathogenesis of AA is comp...

Anemia di Fanconi

G. Patti

2013/7 — pag. 454-455

La mucopolisaccaridosi di tipo I: l’importanza di una diagnosi precoce ai fini dei recenti progressi terapeutici

G. Andria, M. Caniglia, M. Castorina, G.V. Coppa, M. Di Rocco, C. Dionisi Vici, O. Gabrielli, E. Lanino, C. Messina, F. Papadia, R. Parini, A. Rovelli, M. Scarpa, M. Sibilio, M. Spada

2012/6 — pag. 361-370

The present contribution proposes a monograph on Mucopolysaccharidosis type I for the paediatrician. Mucopolysaccharidosis I is one of the most frequent forms of lysosomal storage diseases and is characterized by a wide range of clinical presentati...

Linfoistiocitosi emofagocitica: una sfida diagnostica per il pediatra

E. Sieni, V. Cetica, M. Aricò

2012/1 — pag. 21-29

Haemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory syndrome caused by uncontrolled but ineffective immune response. Inherited human disorders causing the defect of selected proteins involved in the cellular cytotoxicity machinery...

Le vaccinazioni nei bambini oncoematologicidurante e dopo la chemioterapia

Gruppo di Lavoro Terapia di Supporto dell’Associazione Italiana di Emato-Oncologia Pediatrica (AIEOP)

2011/1 — pag. 33-38

Aim - Defining the guidelines on vaccinations in paediatric cancer patients. Method - We reviewed the literature published from 1980 to 2009 according to the methodology suggested by the American Society of Infectious Disease. The intention was to...

ß-talassemia (Parte seconda)

G. Bartolozzi

2006/2

Sette piccoli indiani: riflessioni in merito a sette casi di eritrodermia a esordio precoce

L. D. Notarangelo

2003/8 — pag. 488

Colpire “l’alleato” per uccidere il vermeFarmaci anti-serotonina nella cura dell’intestino irritabileEpatite C nei bambini inglesi e irlandesiÈ divino (ma più ancora è doveroso) sedare il doloreLinfangiomi: OK-432 meglio della chirurgiaL’ereditarietà dell’otite mediaEcografia nel morbo di Crohn: già visto, già detto, già scrittoInterferenze tra vaccini (epatite A e B)Midollo o cellule staminali “periferiche”Infezione e atopia: una voce contro corrente

2000/4 — pag. 215-216

Il trapianto di midollo: un passo avanti per le malattie autoimmuni intrattabili

M. Andolina e coll.

1998/4 — pag. 233-236

We report the results of a series of autologous stem cell transplants in autoimmune diseases. The stem cells were treated ex vivo with vincristine and methylprednisolone as previously in allogeneic mismatched transplants in advanced leukemia. T...