Rivista di formazione e aggiornamento professionale del pediatra e del medico di base, fondata nel 1982. In collaborazione con l'Associazione Culturale Pediatri.
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Problemi speciali

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Un PTT lungo “per caso”

A PROLONGED PTT

Ugo Ramenghi, Giulia Ansaldi, Mirella Davitto

Ematologia, Dipartimento di Scienze Pediatriche, Università di Torino

Giugno 2011 - pagg. 379 -383

Abstract
The aim of this short report is to discuss the abnormality that is more frequently found in coagulation assays, i.e. prolonged aPTT. This is most frequently due to presence of low levels of lupus anticoagulants. This alteration is transient and does not lead to clinical complications. However, in some cases, it may be due to the reduction of coagulation factors, in particular factor VIII, and this may be the only sign of von Willebrand disease. The report should help paediatricians to interpret the main coagulation assays correctly.
Parole chiave
anticoagulanti Anticoagulants Coagulation coagulazione PTT
Suggerite dall'AI
Activated partial thromboplastin time Malattia di von Willebrand Tempo di tromboplastina parziale attivato Von Willebrand disease
Classificazione MeSH
Diagnosis Diagnostic Techniques and Procedures Clinical Laboratory Techniques Hematologic Tests Blood Coagulation Tests (3)
Amino Acids, Peptides, and Proteins Proteins Blood Proteins Blood Coagulation Factors Factor VIII (4)
Amino Acids, Peptides, and Proteins Proteins Blood Proteins Immunoproteins Immunoglobulins Antibodies
Diagnosis Diagnostic Techniques and Procedures Clinical Laboratory Techniques Hematologic Tests Blood Coagulation Tests Partial Thromboplastin Time (6)
Hemic and Lymphatic Diseases Hematologic Diseases Blood Coagulation Disorders Blood Coagulation Disorders, Inherited von Willebrand Diseases (5)
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RI ABC
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Romano F, Del Monte F, Ramenghi U, Parodi E. · 2023
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RI Problemi speciali
Sindromi emorragiche e lupus anticoagulante positivo
L. Facchini, C. Radice, L. Biserna, G. Poletti, F. · 2020
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RI ABC
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Del Monte F, Romano F, Parodi E, Ramenghi U. · 2023
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EL Caso contributivo
Un caso di emofilia acquisita
A. De Cunto, P. Pasquinelli, C. Biasioli, V. Agost · 2011
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RI Pagine elettroniche ; Caso Contributivo
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Bibliografia
•Male C, Lechner K, Eichinger S, et al. Clin- ical significance of lupus anticoagulants in children.J Pediatr 1999;134:199-205.
•Rajpurkar M, Lusher JM. Clinical and labo- ratory approach to the patient with bleeding. In: Nathan and Oski’s Hematology of Infancy and Childhood. Saunders, 2009:1449-62.
•Saracco P, Farinasso L. Coagulazione. In: Madon E, Gabutti V, Miniero R (Eds). Emato- logia e Oncoematologia Pediatrica. Mc Graw- Hill, 1998:170-9.
• Sutor AH. The bleeding time in pediatrics. Semin Thromb Hemost 1998;24:531-43.

Corrispondenza: ugo.ramenghi@unito.it