Aggiornamento
Isolati, multipli, ereditari: le tante facce dei polipi intestinali
Isolated, multiple, and hereditary intestinal polyps in children
Chiara Pierobon1, Marta Flammini1, Valentina Moressa1,2, Stefano Martelossi2, Alessandro Ventura1,2
1Università di Trieste; 2IRCCS Materno-Infantile “Burlo Garofolo”, Trieste
Gennaio 2015 - pagg. 16 -24
Abstract
This article provides a critical review of the clinical presentation, pathology, genetics
and management of the polyposis in childhood starting from the isolated juvenile polyp
to the hereditary polyposis syndromes. These include the juvenile polyposis syndrome,
Peutz-Jeghers syndrome, PTEN hamartoma tumor syndromes and familial adenomatous
polyposis (FAP). These conditions typically outbreak in the second decade of life but early
detection and proper screening and surveillance can minimize the risk of intestinal
and extracolonic cancers. While juvenile polyp could be easily removed, the amartomatosis
syndromes will require a specific endoscopic surveillance and a periodic
polypectomy. In the case of FAP, the paediatrician has a decisive role in defining the
colonscopic follow-up and the timing of the total colectomy.
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Corrispondenza: pierobon.chiara@gmail.com