Rivista di formazione e aggiornamento professionale del pediatra e del medico di base, fondata nel 1982. In collaborazione con l'Associazione Culturale Pediatri.
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Eritroblastopenia transitoria del bambino

TRANSIENT ERYTHROBLASTOPENIA OF CHILDHOOD (TEC)

F. MASSEI, M. NARDI, C. FAVRE, M. MENCONI, G. CASAZZA, P. MACCHIA

Istituto di Clinica Pediatrica, Università di Pisa

Aprile 1998 - pagg. 247 -250

Abstract
The Authors describe the diagnostic, therapeutical and prognostic features of transient erythroblastopenia of childhood (TEC) and report 5 cases. This disorder usually occurs in children aged between 6 mounts and 5 years. The clinical picture is characterized by severe anemia with reticulocytopenia and by the paucity of erythrocyte precursors in the bone marrow. Usually, TEC is preceeded by a viral infection. When Parvovirus B19 is involved as ethiologic factor, neutropenia and thrombocytopenia are also present. Reticulocytopenia may be absent when the child is first seen at the beginning of spontaneous recovery phase. The prognosis is good. Blood transfusion is rarely necessary. The careful observation of the patient is the only medical support really needed in most cases.
Parole chiave
anemia Eritroblastopenia transitoria dell'infanzia parvovirus Transient erythroblastopenia of childhood
Suggerite dall'AI
Parvovirus B19
Classificazione MeSH
Hemic and Lymphatic Diseases Hematologic Diseases Bone Marrow Diseases Bone Marrow Failure Disorders Congenital Bone Marrow Failure Syndromes Anemia, Hypoplastic, Congenital
Diagnosis Diagnostic Techniques and Procedures Clinical Laboratory Techniques Hematologic Tests Bone Marrow Examination (32)
Hemic and Lymphatic Diseases Hematologic Diseases Cytopenia Leukopenia Agranulocytosis Neutropenia (21)
Viruses DNA Viruses Parvoviridae Parvovirinae Erythrovirus Parvovirus B19, Human (25)
Hemic and Lymphatic Diseases Hematologic Diseases Anemia Red-Cell Aplasia, Pure (4)
Hemic and Immune Systems Blood Blood Cells Erythrocytes Reticulocytes (5)
Hemic and Lymphatic Diseases Hematologic Diseases Blood Platelet Disorders Thrombocytopenia (37)
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Bibliografia
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2. Nathan DG, Oski FA (eds): Hematology of infancy and childhood. WB Saunders Co, p. 270, 1993.
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7. Wodzinski MA, et al: Transient eythroblastopenia of childhood due to human parvovirus B19 infection. Br J Haematol 713, 127, 1989.
8. Freedman MH: “Recurrent” erythroblastopenia of childhood. An IgM-mediated RBC aplasia. Am J Dis Child 137, 458, 1983.