Rivista di formazione e aggiornamento professionale del pediatra e del medico di base, fondata nel 1982. In collaborazione con l'Associazione Culturale Pediatri.
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Blood Platelet Disorders

88 articoli — 1997-2026 Include sottocategorie MeSH

EL Casi indimenticabili
Ci fai o ci SEU?

Benigni G, Verticelli T, Pugliese F

2026/3 — pag. 72-73 — DOI

Haemolytic Uremic Syndrome (HUS) is a thrombotic microangiopathy frequently triggered by Shiga toxin-producing E. coli (STEC). This report compares two paediatric cases caused by the same pathogen (E. coli O157:H7) with divergent clinical outcomes. I...

EL Casi indimenticabili
Due fratellini inseparabili con la sindrome emolitica uremica (SEU)

Delcaro G, Dall'Amico R, Tubaro M

2026/1 — pag. 16-16 — DOI

This report describes a familial cluster of typical Haemolytic Uremic Syndrome (HUS) caused by Shiga toxin-producing E. coli (EHEC). An 18-month-old girl initially presented with haemorrhagic diarrhoea, which rapidly progressed to acute renal failure...

EL I Poster degli specializzandi
Accesso libero
Piastrinopenia nel contesto di una intercorrenza infettiva

Zago A

2025/10 — pag. 275-276 — DOI

The paper reports the case of a 10-year-old girl with acute post-infectious thrombocytopenia, presenting with widespread petechiae, ecchymoses and epistaxis, with otherwise normal blood counts. Initial platelet count was 0/mm³. Intravenous immunoglob...

RI Linee guida
Diarrea emorragica acuta, infezione da Escherichia coli produttori di Shiga tossine e sindrome emolitica uremica

Documento d’indirizzo inter-societario

2025/8 — pag. 510-518 — DOI

Haemolytic uremic syndrome (HUS) associated with Shiga toxin-producing Escherichia coli (STEC) infection is a major individual and public health challenge and is the leading cause of acute kidney injury in children. In Western countries, HUS complica...

EL Caso contributivo
Un neonato con piastrinopenia

Starita A

2025/7 — pag. 179-181 — DOI

The paper describes the case of newborn with thrombocytopenia. The final diagnosis is a rare, potentially severe disease that, therefore, should be promptly recognised....

RI Rivista sfogliabile
Rivista sfogliabile on line

2025/6

EL I Poster degli specializzandi
Accesso libero
Trombocitopenia immune: quando le immunoglobuline non funzionano

Iannicelli A, Vorini MV, Beneduce G, Giagnuolo G, Parasole R, Menna G

2025/6 — pag. 162-163 — DOI

A 9-year-old boy was initially evaluated for macrocytic anaemia, neutrophilic leukocytosis and thrombocytopenia, with spontaneous ecchymoses but with no significant medical history. After ten months of follow-up, hematologic worsening occurred alongs...

RI Casi contributivi
Un caso non casuale… di morbillo

Roncareggi S, Cereda C, Paredi M.

2025/5 — pag. 327-328 — DOI

A 9-month-old infant, the second child in the family, presented to the emergency room with a persistent fever lasting six days, accompanied by cough, runny nose and stomatitis. Initial examination revealed generalised malaise, irritability, bilateral...

RI Rivista sfogliabile
Rivista sfogliabile on line

2024/10

RI Casi indimenticabili
Una presentazione atipica della porpora trombocitopenica immune

Leone G, Consentino MC, Pappalardo MG, Leonardi R, Scarlata F, Nannola C, Timpanaro T.

2024/5 — pag. 329-331 — DOI

The authors describe a case of idiopathic autoimmune thrombocytopenia characterized by the onset of visual disturbances due to macular haemorrhage in the left eye....

RI Linee guida
La gestione della piastrinopenia immune acuta in età pediatrica

Parodi E, Russo G. a nome del GdL AIEOP

2024/5 — pag. 313-316 — DOI

This report summarizes the most relevant issues of the document that the Working Group on Coagulation Disorders of the Italian Association of Paediatric Haematology and Oncology (AIEOP) developed to gather shared expert opinions on the management of ...

EL Caso contributivo
Crisi celiaca: una complicanza rara e insidiosa della celiachia

Barca M, Boccia M, Improta M, Discepolo V

2024/4 — pag. 59-63 — DOI

Coeliac Crisis is an urgent and potentially fatal complication of Coeliac Disease (CeD), which is most frequent in early childhood. The crisis may occur at onset or develop in CeD patients with poor compliance to the gluten-free diet (GFD). Stress, s...

RI Problemi speciali
Sindromi, genetica e immunologia: dall’inizio della fine alla fine dell’inizio

Guerra F, Saettini F, Biondi A.

2023/9 — pag. 569-574 — DOI

Syndromic immunodeficiencies are defined as a group of immunodeficiencies in which the immunological defect may be found only in a subgroup of patients. They fall within a more complex clinical picture and may not represent the primary clinical probl...

EL I Poster degli specializzandi
Accesso libero
Un caso complesso di citopenia trilineare ed epatite gigantocellulare

Comella M, Licciardello M, Miraglia V, Russo G

2023/8 — pag. 165-165 — DOI

The case of a five-year-old boy presenting with autoimmune anaemia, neutropenia and thrombocytopenia associated to giant cell hepatitis is described. The diagnosis of ALPS-like syndrome was eventually made....

RI Casi indimenticabili
Infezione da virus di Epstein-Barr: citopenia e colecisti ispessita

Benvenuto S.

2023/4 — pag. 260 — DOI

The author describes the case of a 13-year-old girl presenting with abdominal pain, thrombocytopoenia and neutropoenia. A thickened gallbladder was evident at abdominal sonography. The diagnosis of EBV infection, based on serological investigation, w...

RI ABC
Le prove coagulative nel bambino che sanguina (prima parte)

Del Monte F, Romano F, Parodi E, Ramenghi U.

2023/4 — pag. 249-254 — DOI

This brief report presents a practical approach to the diagnosis of the main coagulopathies in children with haemorrhagic manifestations. It discusses the clinical-anamnestic elements that should suggest further laboratory investigations. Then, after...

EL I Poster degli specializzandi
Accesso libero
Diarrea emorragica: a volte i nodi vengono al pettine tardi

De Crescenzo S, La Scola C, Pillon R, Pasini A, Lami F, Pession A

2023/4 — pag. 72-72 — DOI

The case of a two-year-old girl finally diagnosed with haemolytic uremic syndrome is described....

EL I Poster degli specializzandi
Accesso libero
Una MIS-C come possibile spia di errori congeniti dell’immunità

Drago E, Massaccesi E, Ridella F, Scalas M, Caorsi R, Fioredda F

2023/3 — pag. 52-52 — DOI

The Authors described the case of a 2-year-old child presenting with the typical clinical features of MIS-C finally diagnosed as Wiskott-Aldrich immunodeficiency....

EL Caso contributivo
Un caso insolito di trombocitopenia

Barachino A

2023/1 — pag. 4-5 — DOI

A two-and-a-half-year-old child presents with spontaneous ecchymosis. In addition to severe thrombocytopoenia, initial investigations show the presence of neutropoenia and signs of immune-mediated haemolysis (positivity of the direct antiglobulin tes...

EL I Poster degli specializzandi
Accesso libero
Una crisi convulsiva… emolitica

Posocco F

2022/9 — pag. 193-193 — DOI

The Author describes the case of an 18-month-old child presenting with convulsions and poor general conditions and eventually diagnosed with uraemic-haemolytic syndrome....

RI L'esperienza che insegna
Quando la malaria tarda a farsi riconoscere: un’infezione da Plasmodium ovale

Polenzani I, Lisco L, Cozzolino M, Casolari S, Valenti S, Fontijn S, Uva A, Marchetti F.

2022/6 — pag. 381-385 — DOI

Plasmodium ovale is a cause of non-falciparum malaria infection that is endemic in tropical Western Africa. The life cycle of Plasmodium ovale includes hypnozoites, which are dormant stages in the liver. These stages can be reactivated after weeks, m...

RI Speciale
Nefrologia

Emma F, Pennesi M

2021/26 — pag. 8 — DOI

RI Pagine elettroniche
Tromboembolismo e malattia infiammatoria cronica dell’intestino

Bramuzzo M

2021/2 — pag. 127-129

EL Caso contributivo
Diarrea ematica nel bambino… pensa alla sindrome emolitico-uremica!

R. Letizia, G. Maiorino, M.E. Di Cicco, G.I. Baroncelli, E. De Marco, D. Peroni

2020/7 — pag. 180-185 — DOI

A healthy 5-year-old boy was brought to the Emergency Department with a 24-hour-history of fever, abdominal pain, bloody diarrhoea and vomiting. Blood tests and ultrasound of the abdomen suggested an acute gastroenteritis. The boy was admitted and in...

RI L'angolo degli specializzandi
SEUna diarrea è ematica

A. Bosco, P. Mantovani

2019/10 — pag. 653-655

RI L'esperienza che insegna
Prima la piastrinopenia poi l’embolia polmonare

F. Marchetti, C. Radice, L. Biserna, A.C. Nuzzo, L. Mambelli

2019/10 — pag. 631-633

The paper describes the case of a 17-year-old girl presenting with an initial diagnosis of severe idiopathic thrombocytopoenic purpura with negative ANA and positive Coombs test. After a first phase characterised by thrombocytopeonia with haemorrha...

RI L'esperienza che insegna
Emorragia e trombosi, le due facce del lupus eritematoso sistemico

M. Stinco, T. Giani, I. Maccora, G. Simonini, R. Cimaz

2019/10 — pag. 628-630

Systemic lupus erythematosus (SLE) is an inflammatory disease with autoimmune pathogenesis and chronic-relapsing course characterised by a wide and heterogeneous spectrum of manifestations and sometimes opposed coexisting clinical features. The paper...

RI L'esperienza che insegna
LA COMPLESSITÀ DEL LUPUS ERITEMATOSO SISTEMICO

A. Taddio

2019/10 — pag. 627

RI Percorsi clinici
Piastrinopenia immunomediata in età adolescenziale ed evoluzione in lupus eritematoso sistemico

G. Costagliola, R. Consolini

2018/2 — pag. 97-100

Thrombocytopenia, defined by a platelet count lower than 100,000 mm3, in children and adolescents is more frequently ascribable to an immune pathogenesis (Immune Thrombocytopenia, or ITP). ITP is defined “persistent” if it is still present after th...

RI Rubrica iconografica
Una ragazza con ascite e diarrea con sangue: quale diagnosi?

F. Marchetti, M. Mainetti, M. Giovannini, C. Morelli

2017/8 — pag. 519-522

RI Pagine elettroniche
Due zoppie per due diagnosi

F. Corrias

2017/7 — pag. 465-466

EL I Poster degli specializzandi
Accesso libero
Una porpora (per nulla) spaventosa

S. Carbogno

2016/10

EL I Poster degli specializzandi
Accesso libero
Esordio di lupus eritematoso sistemico con sindrome da attivazione macrofagica, nefrite lupica e microangiopatia trombotica

G. Prunotto, V. Decimi, M.L. Melzi, M.A. Pelagatti, F. Ferrario, A. Biondi

2016/6

RI L'angolo degli specializzandi
Piastrinopenia autoimmune

M. Saruggia, B. Longhi, M. Colombo

2016/5 — pag. 319-321

RI Casi indimenticabili
Quando le piastrine basse possono... attendere

E. Mazzoni, F. Lombardi, C. Fochi, A. Lambertini

2016/5 — pag. 316-318

EL Casi indimenticabili
Nascere con una severa piastrinopenia

L. Mambelli, C. Muratori, G. Piccinini, S. Dal Bo, F. Marchetti

2016/5

EL Casi indimenticabili
Accesso libero
La sindrome di Evans: chi è costei?

F. Pugliese, A. Zucchini, R. Burnelli, F. Marchetti

2015/7

EL Casi indimenticabili
Le macchie di Giorgia

D. Viggiano

2015/2

RI Aggiornamento
Piastrine che scendono, piastrine che salgono: quando preoccuparsi?

E. Parodi, G. Ansaldi, C. Botto, M. Davitto, A. Mondino, C. Olivieri, U. Ramenghi

2013/10 — pag. 629-634

Thrombocytopenia and thrombocytosis are defined by a decreased or an elevated platelet count, respectively. Changes in the platelet number are frequently observed during childhood. This article aims at quickly examining the main causes of thrombocy...

EL Caso contributivo
Trombocitopenia neonatale alloimmune HLA correlata

G. Melis, M.R. Gallina, P. Rosetta, I. Paolucci, V. Raffa, F. Ferrero, A. Guala

2013/10

Neonatal allo-immune thrombocytopoenia (NAIT) is a pathology caused by the passage of maternal antibodies against fetal platelet antigens through the placenta. The role of platelet-specific antigens of paternal origin (HPA - Human Platelet Antigen) a...

EL Casi indimenticabili
Un’anemia da sfera di cristallo

V. Dal Cengio, M. Bellettato

2013/7

EL Casi indimenticabili
Cicli da indagare (anamnesi e ancora anamnesi)

A. Paladini, G. La Fauci, M. Fornaro, E. Valletta

2013/5

RI Ricerca
La sindrome mononucleosica: revisione di 107 casi

C. Geraci, M. Pocecco

2012/8 — pag. 521-523

Childhood infectious mononucleosis is a benign and self-limited disease. Complications are rare but not unremarkable: 3 out of 107 patients experienced haematological complications (1 autoimmune haemolytic anaemia and 2 autoimmune thrombocytopenia)...

EL I Poster degli specializzandi
Accesso libero
Trombocitopenia da acido valproico o da infezione virale?

E. Gnoato, S. Masiero, C. Moretti

2012/6

EL Pediatria per immagini
Accesso libero
La pediatria per sigle: un neonato con il RICH

L. Mambelli, L. Pini, M. Baruzzi, F. Marchetti, F. Arcangeli

2012/5

RI Casi indimenticabili
Caverne

E. Ugolini, P. Fioretti

2012/4 — pag. 259-260

RI Problemi speciali
Un PTT lungo “per caso”

U. Ramenghi, G. Ansaldi, M. Davitto

2011/6 — pag. 379-383

The aim of this short report is to discuss the abnormality that is more frequently found in coagulation assays, i.e. prolonged aPTT. This is most frequently due to presence of low levels of lupus anticoagulants. This alteration is transient and d...

EL Casi indimenticabili
Una banale gastroenterite?

A. Paladini, S. Ciccone, C. Farneti

2010/10

RI Farmacoriflessioni
Utilizzo delle immunoglobuline endovenose nella pratica clinica in pediatria

G. Ventura, M. Rabusin, E. Spinelli, R. Badolato

2009/6 — pag. 371-381

Intravenous immunoglobuline is a blood product prepared from the serum of between 1,000 and 15,000 donors per batch. It is the treatment indicated for patients with antibody deficiencies and it is used in replacement doses of 200-400 mg/kg. In cont...

RI Pagine elettroniche ; Caso Contributivo
Un caso di zoppia

C. Galletto, N. Bertorello, E. Barisone, R. Mazzone, A. Andreacchio

2007/1 — pag. 51-53

In childhood and adolescence articular pains are frequent and in most of the cases they disappear rapidly and spontaneously. In a few patients the cause of the symptoms is an organic and/or a systemic pathology that require accurate examination a...

RI Pagine elettroniche ; Caso Contributivo
Un caso di polmonite con piastrinosi

F. De Maddi, C. Santoro, R. Crusco, P. Siani

2006/10 — pag. 667

The Authors describe a case of pneumonia in an 11 months old child, who presented with high inflammatory indexes. Antibiotic response was quick, with rapid improvement of symptoms, fever resolution in 72 hours and resolution of the radiological pneum...

EL Striscia... la notizia
Accesso libero
TUTTE LE NOTIZIE

I. Bruno

2005/2

RI Pagine elettroniche
Quando una sepsi neonatale nasconde una malattia metabolica

C. Forino, C. Rodriguez-Perez

2005/1 — pag. 58-58

A 50-day-old boy presented with failure to thrive, hypotonia, pustular lesions and facial erythema, neutropenia and multiple positive cultures to Staphylococcus aureus. He was treated with intravenous antibiotics without clinical benefit. He devel...

RI Pagine elettroniche
Manifestazioni ematologiche nelle malattie mitocondriali con mutazione dell’mt-DNA

R. Cerchio, F. Timeus, P. Saracco, et al.

2005/1 — pag. 57-58

We report a 10-month-old girl who, at the age of 4 months, was admitted for increasing pallor. Severe normocytic anaemia, neutropenia and thrombocytopenia and typical diffuse vacuolization of marrow haemopoietic precursors were present. She also ...

EL Pediatria per l'ospedale
Accesso libero
Emofilia A e B1° parte

G. Bartolozzi

2004/11

EL Contributi Originali - Casi contributivi
Accesso libero
Piastrinopenia isolata x-linked da mutazione missense del gene WASP: descrizione di un caso

C Locatelli, C Malaventura, R Ciambra, M Pocecco, L. D Notarangelo, L. D Notarangelo

2004/7

EL Contributi Originali - Casi contributivi
Accesso libero
PIastrinopenia isolata x-linked da mutazione missense del gene Wasp: descrizione di un caso

C Locatelli, C Malaventura, R Ciambra, M Pocecco, L. D Notarangelo, L. D Notarangelo

2004/7

RI Pagine elettroniche
Piastrinopenia isolata X-linked da mutazione del gene WASP

2004/7 — pag. 450-450

Wiskott-Aldrich (WAS) and X-linked thrombocytopenia (XLT) are two disorders caused by different mutations of the gene WASP. WAS is characterized by recurrent infections, eczema, thrombocytopenia with low mean platet volume (MPV) and increased sus...

EL Avanzi
Accesso libero
Desametazone ad alte dosi nella porpora trombocitopenica immune

G. Bartolozzi

2003/8

RI Problemi non correnti
Sette lattanti rossi: dalla dermatite atopica ai difetti congeniti dell’immunità

E. Zamuner, A. Tommasini

2003/8 — pag. 512-516

Seven infants with severe dermatitis, diarrhoea and/or infections are described. A primary immunodeficiency (PID) was considered among the diagnostic hypotheses in all cases. Thrombocytopenia, hypereosinophilia, lymphopenia and Ig deficiencies were...

EL Contributi Originali - Casi contributivi
Accesso libero
Trombocitosi grave e anemia sideropenica: un caso clinico

E. Miorin, F. Colonna

2003/4

RI Pagine elettroniche
Trombocitosi e anemia sideropenica: un caso clinico

2003/4 — pag. 258

We report a case of a 11-year-old boy with a silent thrombocytosis associated to iron deficiency anemia. Iron deficiency anemia is a known cause of increased platelet counts but the mechanisms causing this reactive thrombocytosis are unclear, perh...

EL Pediatria per l'ospedale
Accesso libero
Le malattie del viaggiatore (parte terza)

G. Bartolozzi

2003/1

RI Pagine elettroniche
Accesso libero
Piastrinopenia cronica multiresistente in bambina con sindrome linfoproliferativa autoimmune (ALPS): efficacia della ciclofosfamide

E. Barth, M. Rabusin, GA. Zanazzo, P. Tamaro

2001/8 — pag. 548-548

Report of a very severe case of thrombocytopenia with lymphoproliferative autoimmune syndrome (hereditary ALPS) resistant to classical treatments, both in high doses or bolus, with prompt and durable response to cyclophosfamide....

RI Casi indimenticabili
Accesso libero
Una lunga orticaria sfociata in una malattia sistemica

L. Lepore

2000/5 — pag. 316-318

RI Focus
Accesso libero
Lupus neonatale: una patologia autoimmune trasferita per via placentare

R. Cimaz, B. Speroni, P. Careddu

1999/6 — pag. 365-370

RI Pagina verde
Accesso libero
Un caso di polmonite tipica da mycoplasma

L. Gnemmi, M. Pocecco

1999/4 — pag. 217-218

RI Casi indimenticabili
Accesso libero
L'eczema di Piero

F. Fusco

1999/3 — pag. 191-192

RI Pagina verde
Accesso libero
La sindrome cfc: un caso con piastrinopenia

A. Borrelli, G. Pinto

1999/3 — pag. 149

RI Problemi non correnti
Accesso libero
Eritroblastopenia transitoria del bambino

F. Massei, M. Nardi, C. Favre e coll.

1998/4 — pag. 247-250

The Authors describe the diagnostic, therapeutical and prognostic features of transient erythroblastopenia of childhood (TEC) and report 5 cases. This disorder usually occurs in children aged between 6 mounts and 5 years. The clinical picture is...