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Short parents, short children - more on familial short stature
Gianluca Tornese
SCU di Clinica Pediatrica, SS di Endocrinologia, Diabetologia e Altre Malattie del Metabolismo, IRCCS Materno-Infantile “Burlo Garofolo”, Trieste
Settembre 2019 - pagg. 431 -437
Abstract
Familial short stature is the second cause of short stature immediately after constitutional
delay of growth and puberty. So far, in case of familiarity for short stature, regular
growth velocity, bone age compatible with chronological age, the indication has been
not to carry out further investigations. The advent of next generation sequencing has revolutionized,
among others, the field of short stature, and many children with familial
short stature could have a mutated gene that could benefit from growth hormone therapy
(i.e. SHOX, IHH, PTPN11...).
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Corrispondenza: gianluca.tornese@burlo.trieste.it
