Bone Marrow Examination

Trombocitopenia immune: quando le immunoglobuline non funzionano

Iannicelli A, Vorini MV, Beneduce G, Giagnuolo G, Parasole R, Menna G

2025/6 — pag. 162-163 — DOI

A 9-year-old boy was initially evaluated for macrocytic anaemia, neutrophilic leukocytosis and thrombocytopenia, with spontaneous ecchymoses but with no significant medical history. After ten months of follow-up, hematologic worsening occurred alongs...

"Amici per la pelle": un caso di leishmaniosi

Fantasia M, Vecchi M, Cavalleri L, Bruni F, Provenzi M

2025/4 — pag. 81-85 — DOI

Leishmaniasis is an infectious disease caused by protozoa of the Leishmania genus, parasites of humans and several domestic and wild animals, and transmitted via vectors. The authors describe the case of an 18-month-old girl, presenting to the Emerge...

Leishmania e linfoistiocitosi emofagocitica (HLH)

Bratta A, Arcuri L, Micalizzi C

2025/2 — pag. 51-52 — DOI

Haemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening hyperinflammatory syndrome. The paper reports the case of a 5-month-old infant hospitalised with persistent fever, splenomegaly and significant inflammatory activation. After an ini...

Un caso di anemia macrocitica non megaloblastica: la sindrome di Blackfan Diamond

Aquisti G, Basso ME, Rabbone I

2024/5 — pag. 92-93 — DOI

The case of a two-year-old child with severe isolated anaemia (6 g%) and marked macrocytosis, ultimately diagnosed as Blackfan Diamond syndrome, is described. The genetic, clinical and prognostic aspects of the disease are briefly discussed....

Quando l’anemia viene da un’infezione da parvovirus

Tolomelli E, Legnani E, Grasso A

2023/3 — pag. 53-53 — DOI

The author describes the case of a 2-year-old boy presenting with aplastic anaemia due to documented parvovirus infection of the bone marrow without a specific seroconversion....

Quando la linfoistiocitosi emofagocitica è secondaria

Ventresca S, Fabbri E, Bracaglia C, Gasperini P, Filippini B, Libertucci F, Bigucci B, Pericoli R, Vergine G.

2022/2 — pag. 97-102 — DOI

The paper describes the case of a 1-year-old Caucasian boy with a 1-month history of fever and splenomegaly. Laboratory findings showed pancytopenia, hypertriglyceridemia and hyperferritinemia. Secondary haemophagocytic lymphohistiocytosis was suspec...

La sindrome di Chediak-Higashi a esordio tardivo

Ciancia S, Dalla Porta MF, Cingolani GM, Cellini M, Soresina A, Badolato R, Mariotti I, Cano Garcinuno MdC, Iughetti L

2021/4 — pag. 118-123 — DOI

Chediak-Higashi syndrome (CHS) is a rare autosomal recessive disorder caused by mutations in the CHS1/LYST gene, encoding for LYST protein, involved in lysosomal trafficking. It is characterized by recurrent bacterial infections, oculocutaneous albin...

Un’emolisi ben mascherata

G. Del Borrello

2018/6

Chronic haemolytic anaemia is a pathophysiological process that can be the expression of many possible etiologies (e.g. a congenital defect of a membrane protein, immune-mediated destruction, enzymopathies, altered erythrocyte development). The paper...

Leucemia linfoblastica acuta del bambino: al bivio tra successi e interrogativi

A. Biondi

2017/7 — pag. 415

Ipereosinofilia severa: un caso da non dimenticare

E. Santi

2017/6

Mi fa male la schiena

S. Amoroso

2017/5

Brucellosi: un raro caso di recidiva

M.C. Castiglione

2017/1

Piastrinopenia autoimmune

M. Saruggia, B. Longhi, M. Colombo

2016/5 — pag. 319-321

Cosa deve sapere il pediatra della linfoistiocitosi emofagocitica attraverso i casi degli specializzandi

S. Lega, F. Dell’Acqua, M. Minute, F. Vendemini, C. Cattelani

2015/7 — pag. 431-441

Hemophagocytic lymphohistiocytosis (HLH) is a potentially life-threatening syndrome caused by severe hypercytokinemia due to a highly stimulated but ineffective immune response. HLH is not a disease by its own but is rather a common final consequen...

Una febbre alta e persistente con epatosplenomegalia e citopenia

L. de Seta, M.S. Sabatino, F. de Seta, P. Siani

2015/7 — pag. 431-441

The case described is that of an 11-year-old child presenting with high fever, pharyngotonsillar exudate, submandibular strangles and hepatosplenomegaly. The elevated number of VCA IgM antibodies led to a diagnosis of infectious mononucleosis. The ...

Dolore alle ossa, febbricola e aumento degli indici di flogosi: pensare anche alla osteomielite cronica multifocale ricorrente

M. Cappella, S. dal Bo, L. Berretti, F. Ravaioli, R. Burnelli, F. Marchetti

2014/7

The paper reports the case of a 7-year-old child who pre-sented with recurrent multifocal bone pain associated with low fever, elevation of flogosis indexes and negative standard radiological exams. The spectrum of differential diagnosis was wide. Th...

Leishmania: un parassita, molte infezioni

S. Virano, D. Le Serre, S. Garazzino, E. Silvestro, P.A. Tovo

2012/8

A 10-year-old child presented with persistent fever, relevant hepatosplenomegaly and pancytopenia. Abdominal US imaging, serology for most relevant pathogens and Leishmania, PCR for Parvovirus B19 and bone marrow sample were performed in order to...

Una comunicazione difficile e una diagnosi scritta in cinese

C. Landini, E. Mazzoni, A. Lambertini

2010/3

Leucemia linfoblastica acuta all\'esordio: quando nel dubbio è meglio fare...

G. Fusilli, V. Cecinati, G. Merico, M. Anna Piccione, G. Sarli, A. Granieri, G. Labalestra, F. Sarli, G. Russo, N. Santoro, D. De Mattia

2009/9

Leucemia linfoblastica acuta all’esordio: quando nel dubbio è meglio fare…

G. Fusilli, V. Cecinati, G. Merico, M.A. Piccione, G. Sarli, A. Granieri, G. Labalestra, F. Sarli, G. Russo, N. Santoro, D. De Mattia

2009/9 — pag. 597-598

Acute lymphoblastic leukemia is the most common malignancy diagnosed in children. We report the case of a female patient presenting with asthenia and limb pain when admitted to our Operative Unit of Pediatrics. Laboratory studies showed high leve...

La splenomegalia

M. Rabusin, F. Patarino

2007/8 — pag. 493-499

The spleen in infants and children is involved in a wide variety of pathological conditions. Splenic disorders may be isolated like splenic cysts or, more frequently, due to multiorgan or systemic disease including hepatic diseases, malignancy, hemo...

Un caso di eritrofagocitosi secondaria a leishmaniosi nell’entroterra friulano

F. Minen, C. Oretti, F. Marchetti, G. Zanazzo, M. Maschio, D. Lizzi, A Ventura

2007/5 — pag. 325-327

The present report describes the case of a 2-year-old girl that lives in Northern Italy suffering from a one month lasting fever, pallor and hepatosplenomegaly. Serum testing showed pancytopenia, high levels of immunoglobulins, hypertriglyceridemia a...

Un caso di zoppia

C. Galletto, N. Bertorello, E. Barisone, R. Mazzone, A. Andreacchio

2007/1 — pag. 51-53

In childhood and adolescence articular pains are frequent and in most of the cases they disappear rapidly and spontaneously. In a few patients the cause of the symptoms is an organic and/or a systemic pathology that require accurate examination a...

Manifestazioni ematologiche nelle malattie mitocondriali con mutazione dell’mt-DNA

R. Cerchio, F. Timeus, P. Saracco, et al.

2005/1 — pag. 57-58

We report a 10-month-old girl who, at the age of 4 months, was admitted for increasing pallor. Severe normocytic anaemia, neutropenia and thrombocytopenia and typical diffuse vacuolization of marrow haemopoietic precursors were present. She also ...

Sedazioni Profonde e ripetute in emato-oncologia:vissuto dei bambini affetti da leucemia e delle loro famiglie

L. Bana, I. Bruno, T. Geraraduzzi, E. Biasotto, I. Giuseppin, I. Berti, G. Zanazzo, M. Rabusin, R. Vecchi, E. Barbi, A. Sarti, P. Tamaro, A. Ventura.

2004/11

Sedazioni profonde ripetute in Emato-oncologia: vissuto dei bambini affetti da leucemia e delle loro famiglie

2004/11 — pag. 723-725

Painful procedures are a major source of distress for children with leukaemia and for their parents. Procedural sedation, and possibly deep sedation, is recommended for these patients. The aim of this study was to evaluate the attitudes of patient...

La paura e il dolore inevitabili

E. Barbi

2004/11 — pag. 675-676

Una bambina con febbre e dolore alle ossa

S. Bassanese, T. Gerarduzzi, F. Marchetti

2004/4

Una splenomegalia febbrile con neutropenia

C. Malorgio

1998/9

Una splenomegalia febbrile con neutropenia

P. Tamaro, C. Malorgio

1998/9 — pag. 581

Eritroblastopenia transitoria del bambino

F. Massei, M. Nardi, C. Favre e coll.

1998/4 — pag. 247-250

The Authors describe the diagnostic, therapeutical and prognostic features of transient erythroblastopenia of childhood (TEC) and report 5 cases. This disorder usually occurs in children aged between 6 mounts and 5 years. The clinical picture is...