Thrombocytopenia

Ci fai o ci SEU?

Benigni G, Verticelli T, Pugliese F

2026/3 — pag. 72-73 — DOI

Haemolytic Uremic Syndrome (HUS) is a thrombotic microangiopathy frequently triggered by Shiga toxin-producing E. coli (STEC). This report compares two paediatric cases caused by the same pathogen (E. coli O157:H7) with divergent clinical outcomes. I...

Piastrinopenia nel contesto di una intercorrenza infettiva

Zago A

2025/10 — pag. 275-276 — DOI

The paper reports the case of a 10-year-old girl with acute post-infectious thrombocytopenia, presenting with widespread petechiae, ecchymoses and epistaxis, with otherwise normal blood counts. Initial platelet count was 0/mm³. Intravenous immunoglob...

Occhio all'emocromo... prima che sia tardi

Di Noto F, Lo Meo F, Marra G, Dimartino G, Gilotta C, Genduso M, Ferraro T, Allegra M, Guarina A, Cardella F, Corsello G

2025/7 — pag. 190-191 — DOI

A 5-year-old boy, presented with hematemesis, diffuse petechiae, epistaxis, respiratory distress and severe pancytopenia. After poor response to immunoglobulin and steroid therapy, bone marrow evaluation revealed trilineage cytopenia. The combination...

Splenomegalia e malattia di Gaucher

Piccioni A, Santoro L, Bruschi B, Lionetti ME, Pugliese F

2025/7 — pag. 187-187 — DOI

A 4-year-old girl, asymptomatic and in good general health, is referred to a paediatric Haemato-Oncology centre for splenomegaly associated with mild anaemia and thrombocytopenia. Initial suspicion of leukaemia is ruled out after thorough clinical, l...

Un neonato con piastrinopenia

Starita A

2025/7 — pag. 179-181 — DOI

The paper describes the case of newborn with thrombocytopenia. The final diagnosis is a rare, potentially severe disease that, therefore, should be promptly recognised....

Rivista sfogliabile on line

2025/6

Un caso non casuale… di morbillo

Roncareggi S, Cereda C, Paredi M.

2025/5 — pag. 327-328 — DOI

A 9-month-old infant, the second child in the family, presented to the emergency room with a persistent fever lasting six days, accompanied by cough, runny nose and stomatitis. Initial examination revealed generalised malaise, irritability, bilateral...

Rivista sfogliabile on line

2024/10

Una trombocitopenia associata alla scabbia in un neonato: caso clinico e revisione della letteratura

Giulia La Malfa

2024/10 — pag. 220-222 — DOI

The paper presents the case of a 1-month-old infant with persistent skin lesions who was diagnosed with scabies after initial ineffective treatments. The condition was linked to thrombocytopenia and anaemia, which resolved following dermatologic ther...

Una strana pancitopenia: dalla gestione in urgenza alla diagnosi genetica

Di Filippo M, Rossoni L, Nebiolo M, Fioredda F, Carrato V, Pirlo D

2024/10 — pag. 201-206 — DOI

Wiskott-Aldrich syndrome (WAS) is a rare X-linked genetic disorder caused by a mutation in the WAS gene that codes for the WASp protein, which is involved in the functioning of the cytoskeleton of non-erythroid haematopoietic cells. This mutation lea...

Una presentazione atipica della porpora trombocitopenica immune

Leone G, Consentino MC, Pappalardo MG, Leonardi R, Scarlata F, Nannola C, Timpanaro T.

2024/5 — pag. 329-331 — DOI

The authors describe a case of idiopathic autoimmune thrombocytopenia characterized by the onset of visual disturbances due to macular haemorrhage in the left eye....

La gestione della piastrinopenia immune acuta in età pediatrica

Parodi E, Russo G. a nome del GdL AIEOP

2024/5 — pag. 313-316 — DOI

This report summarizes the most relevant issues of the document that the Working Group on Coagulation Disorders of the Italian Association of Paediatric Haematology and Oncology (AIEOP) developed to gather shared expert opinions on the management of ...

Crisi celiaca: una complicanza rara e insidiosa della celiachia

Barca M, Boccia M, Improta M, Discepolo V

2024/4 — pag. 59-63 — DOI

Coeliac Crisis is an urgent and potentially fatal complication of Coeliac Disease (CeD), which is most frequent in early childhood. The crisis may occur at onset or develop in CeD patients with poor compliance to the gluten-free diet (GFD). Stress, s...

Questioni di lacrime

Balestra E, Trombetta A.

2023/9 — pag. 599 — DOI

Un caso complesso di citopenia trilineare ed epatite gigantocellulare

Comella M, Licciardello M, Miraglia V, Russo G

2023/8 — pag. 165-165 — DOI

The case of a five-year-old boy presenting with autoimmune anaemia, neutropenia and thrombocytopenia associated to giant cell hepatitis is described. The diagnosis of ALPS-like syndrome was eventually made....

Infezione da virus di Epstein-Barr: citopenia e colecisti ispessita

Benvenuto S.

2023/4 — pag. 260 — DOI

The author describes the case of a 13-year-old girl presenting with abdominal pain, thrombocytopoenia and neutropoenia. A thickened gallbladder was evident at abdominal sonography. The diagnosis of EBV infection, based on serological investigation, w...

Diarrea emorragica: a volte i nodi vengono al pettine tardi

De Crescenzo S, La Scola C, Pillon R, Pasini A, Lami F, Pession A

2023/4 — pag. 72-72 — DOI

The case of a two-year-old girl finally diagnosed with haemolytic uremic syndrome is described....

Una MIS-C come possibile spia di errori congeniti dell’immunità

Drago E, Massaccesi E, Ridella F, Scalas M, Caorsi R, Fioredda F

2023/3 — pag. 52-52 — DOI

The Authors described the case of a 2-year-old child presenting with the typical clinical features of MIS-C finally diagnosed as Wiskott-Aldrich immunodeficiency....

Un caso insolito di trombocitopenia

Barachino A

2023/1 — pag. 4-5 — DOI

A two-and-a-half-year-old child presents with spontaneous ecchymosis. In addition to severe thrombocytopoenia, initial investigations show the presence of neutropoenia and signs of immune-mediated haemolysis (positivity of the direct antiglobulin tes...

Macrotrombocitopenia, dismorfismi facciali e ritardo dello sviluppo psicomotorio: alla scoperta del gene CDC42

Fabbri E, Giardinelli S, Filippini B, Gasperini P, Mazzocco M, Radice C, Marchetti F, Pericoli R

2022/9 — pag. 181-186 — DOI

Cell Division Control 42 (CDC42) gene encodes for a small GTPase with a fundamental role in controlling intracellular signaling pathway. Gene mutations can cause different phenotypic manifestations, which reflect the variety of the role of this media...

Quando la malaria tarda a farsi riconoscere: un’infezione da Plasmodium ovale

Polenzani I, Lisco L, Cozzolino M, Casolari S, Valenti S, Fontijn S, Uva A, Marchetti F.

2022/6 — pag. 381-385 — DOI

Plasmodium ovale is a cause of non-falciparum malaria infection that is endemic in tropical Western Africa. The life cycle of Plasmodium ovale includes hypnozoites, which are dormant stages in the liver. These stages can be reactivated after weeks, m...

Una grave anemizzazione

M. Cognigni

2020/9 — pag. 599 — DOI

CAMT: trombocitopenia amegacariocitica congenita

V. Carrato

2020/9 — pag. 239-239 — DOI

Diarrea ematica nel bambino… pensa alla sindrome emolitico-uremica!

R. Letizia, G. Maiorino, M.E. Di Cicco, G.I. Baroncelli, E. De Marco, D. Peroni

2020/7 — pag. 180-185 — DOI

A healthy 5-year-old boy was brought to the Emergency Department with a 24-hour-history of fever, abdominal pain, bloody diarrhoea and vomiting. Blood tests and ultrasound of the abdomen suggested an acute gastroenteritis. The boy was admitted and in...

Prima la piastrinopenia poi l’embolia polmonare

F. Marchetti, C. Radice, L. Biserna, A.C. Nuzzo, L. Mambelli

2019/10 — pag. 631-633

The paper describes the case of a 17-year-old girl presenting with an initial diagnosis of severe idiopathic thrombocytopoenic purpura with negative ANA and positive Coombs test. After a first phase characterised by thrombocytopeonia with haemorrha...

LA COMPLESSITÀ DEL LUPUS ERITEMATOSO SISTEMICO

A. Taddio

2019/10 — pag. 627

Cerchi una celiachia, trovi... una leucemia

S. Molinari

2018/6

Piastrinopenia immunomediata in età adolescenziale ed evoluzione in lupus eritematoso sistemico

G. Costagliola, R. Consolini

2018/2 — pag. 97-100

Thrombocytopenia, defined by a platelet count lower than 100,000 mm3, in children and adolescents is more frequently ascribable to an immune pathogenesis (Immune Thrombocytopenia, or ITP). ITP is defined “persistent” if it is still present after th...

Una ragazza con ascite e diarrea con sangue: quale diagnosi?

F. Marchetti, M. Mainetti, M. Giovannini, C. Morelli

2017/8 — pag. 519-522

Due storie di malaria: c’è sempre da imparare

M.T. Bartolini, C. Ghizzi

2017/8

Due zoppie per due diagnosi

F. Corrias

2017/7 — pag. 465-466

MAS in WAS? (una Wiskott-Aldrich non convenzionale)

S. Amoroso

2016/10

Quando le piastrine basse possono... attendere

E. Mazzoni, F. Lombardi, C. Fochi, A. Lambertini

2016/5 — pag. 316-318

La sindrome di Evans: chi è costei?

F. Pugliese, A. Zucchini, R. Burnelli, F. Marchetti

2015/7

Il sale della vita: esami di laboratorio nelle IVU?

G. Bassanese, S. Norbedo, M. Pennesi

2014/5

Severe hyponatremia has been reported as a possible complication in children with renal dysplasia and urinary tract infection (UTI). The pathogenesis of this conditions is probably due to concomitant events such as renal parenchima flogosis and the i...

Al di là dell’occhio!

G. Ferrara, E. Zanelli

2014/3

Trauma contusivo addominale

G. Ferrara, P. Assandro, L. Calligaris, F. Zennaro, M.G. Scarpa, E. Barbi

2014/2 — pag. 97-103

Blunt abdominal trauma is a common presentation in the emergency unit and still remains a leading cause of death in children older than one year of age. The spleen is the most commonly injured but other solid organs or bowel may be interested, so e...

Piastrine che scendono, piastrine che salgono: quando preoccuparsi?

E. Parodi, G. Ansaldi, C. Botto, M. Davitto, A. Mondino, C. Olivieri, U. Ramenghi

2013/10 — pag. 629-634

Thrombocytopenia and thrombocytosis are defined by a decreased or an elevated platelet count, respectively. Changes in the platelet number are frequently observed during childhood. This article aims at quickly examining the main causes of thrombocy...

La sindrome mononucleosica: revisione di 107 casi

C. Geraci, M. Pocecco

2012/8 — pag. 521-523

Childhood infectious mononucleosis is a benign and self-limited disease. Complications are rare but not unremarkable: 3 out of 107 patients experienced haematological complications (1 autoimmune haemolytic anaemia and 2 autoimmune thrombocytopenia)...

Non sempre epistassi ed ecchimosi indicano una porpora

G. Sanna, D. Ticca, V. Manca, L. Buono

2012/7

Trombocitopenia da acido valproico o da infezione virale?

E. Gnoato, S. Masiero, C. Moretti

2012/6

La pediatria per sigle: un neonato con il RICH

L. Mambelli, L. Pini, M. Baruzzi, F. Marchetti, F. Arcangeli

2012/5

Un male dell'altro mondo

S. Lasagni, G. Boschi, I. Dodi, M.A. Bandello, A. Defanti, S. Amarri

2012/5

Caverne

E. Ugolini, P. Fioretti

2012/4 — pag. 259-260

Una banale gastroenterite?

A. Paladini, S. Ciccone, C. Farneti

2010/10

Addome acuto a sorpresa

I. Giuseppin, M. Ranieri, P. Flora

2010/3

Quando le vitamine servono davvero

F. Lombardi, A.L. Quitadamo, A. Pelizzoni, P. Accorsi, F. Olivetti

2010/2

Ben nutriti da morire: ovvero bambini obesi e cardiopatia coronarica precoce Trapianto di polmone in bambini con fibrosi cistica: pausa di riflessione? “Parolacce” da imparare: Eltrombopag Complicazioni gravi e ricovero ospedaliero in corso di varicella Vaccino orale contro il Rotavirus: olé Globalizzazione: ovvero Chikungunya in Romagna Test rapido e screening per la celiachia, infermiere e… ragazzi della via Pal

2007/10 — pag. 623-624

Un caso di zoppia

C. Galletto, N. Bertorello, E. Barisone, R. Mazzone, A. Andreacchio

2007/1

Un caso di zoppia

C. Galletto, N. Bertorello, E. Barisone, R. Mazzone, A. Andreacchio

2007/1 — pag. 51-53

In childhood and adolescence articular pains are frequent and in most of the cases they disappear rapidly and spontaneously. In a few patients the cause of the symptoms is an organic and/or a systemic pathology that require accurate examination a...

Un caso di polmonite con piastrinosi

F. De Maddi, C. Santoro, R. Crusco, P. Siani

2006/10

Quando una sepsi neonatale nasconde una malattia metabolica

C. Forino, C. Rodriguez-Perez

2005/1 — pag. 58-58

A 50-day-old boy presented with failure to thrive, hypotonia, pustular lesions and facial erythema, neutropenia and multiple positive cultures to Staphylococcus aureus. He was treated with intravenous antibiotics without clinical benefit. He devel...

Manifestazioni ematologiche nelle malattie mitocondriali con mutazione dell’mt-DNA

R. Cerchio, F. Timeus, P. Saracco, et al.

2005/1 — pag. 57-58

We report a 10-month-old girl who, at the age of 4 months, was admitted for increasing pallor. Severe normocytic anaemia, neutropenia and thrombocytopenia and typical diffuse vacuolization of marrow haemopoietic precursors were present. She also ...

Una bambina con artrite reumatoide sistemica e febbre: è una ricaduta?

C. Oretti, M. Maschio, M. Lazzerini

2004/9

Piastrinopenia isolata x-linked da mutazione missense del gene WASP: descrizione di un caso

C Locatelli, C Malaventura, R Ciambra, M Pocecco, L. D Notarangelo, L. D Notarangelo

2004/7

PIastrinopenia isolata x-linked da mutazione missense del gene Wasp: descrizione di un caso

C Locatelli, C Malaventura, R Ciambra, M Pocecco, L. D Notarangelo, L. D Notarangelo

2004/7

Piastrinopenia isolata X-linked da mutazione del gene WASP

2004/7 — pag. 450-450

Wiskott-Aldrich (WAS) and X-linked thrombocytopenia (XLT) are two disorders caused by different mutations of the gene WASP. WAS is characterized by recurrent infections, eczema, thrombocytopenia with low mean platet volume (MPV) and increased sus...

Desametazone ad alte dosi nella porpora trombocitopenica immune

G. Bartolozzi

2003/8

Sette lattanti rossi: dalla dermatite atopica ai difetti congeniti dell’immunità

E. Zamuner, A. Tommasini

2003/8 — pag. 512-516

Seven infants with severe dermatitis, diarrhoea and/or infections are described. A primary immunodeficiency (PID) was considered among the diagnostic hypotheses in all cases. Thrombocytopenia, hypereosinophilia, lymphopenia and Ig deficiencies were...

La storia di Fabio

A. Pinti

2003/3 — pag. 193-195

Piastrinopenia cronica multiresistente in bambina con sindrome linfoproliferativa autoimmune (ALPS). Efficacia della ciclofosfamide

E. Barth, M. Rabusin G.A. Zanazzo, P. Tamaro

2001/8

Un caso clinico dalla letteratura internazionale, con integrazioni patogenetico-cliniche

G. Bartolozzi

2001/8

Piastrinopenia cronica multiresistente in bambina con sindrome linfoproliferativa autoimmune (ALPS): efficacia della ciclofosfamide

E. Barth, M. Rabusin, GA. Zanazzo, P. Tamaro

2001/8 — pag. 548-548

Report of a very severe case of thrombocytopenia with lymphoproliferative autoimmune syndrome (hereditary ALPS) resistant to classical treatments, both in high doses or bolus, with prompt and durable response to cyclophosfamide....

Una lunga orticaria sfociata in una malattia sistemica

L. Lepore

2000/5 — pag. 316-318

Lupus neonatale: una patologia autoimmune trasferita per via placentare

R. Cimaz, B. Speroni, P. Careddu

1999/6 — pag. 365-370

Un caso di polmonite “tipica” da mycoplasma

L. Gnemmi, M. Pocecco

1999/4

Un caso di polmonite tipica da mycoplasma

L. Gnemmi, M. Pocecco

1999/4 — pag. 217-218

La sindrome CFC (Cardio-facio-cutaneous syndrome): un caso con piastrinopenia

A. Borrelli, G. Pinto

1999/3

L'eczema di Piero

F. Fusco

1999/3 — pag. 191-192

La sindrome cfc: un caso con piastrinopenia

A. Borrelli, G. Pinto

1999/3 — pag. 149

La trombopoietinaFibrosi cistica e iperossaluriaQuale cura per la fimosi ?

G. Bartolozzi

1998/9

PEDIATRIA DI GRUPPO: A CHE PUNTO SIAMOIl gruppo di Bergamo

G. Caso, B.M. Marengoni, L. Venturelli

1998/7 — pag. 441-444

Eritroblastopenia transitoria del bambino

F. Massei, M. Nardi, C. Favre e coll.

1998/4 — pag. 247-250

The Authors describe the diagnostic, therapeutical and prognostic features of transient erythroblastopenia of childhood (TEC) and report 5 cases. This disorder usually occurs in children aged between 6 mounts and 5 years. The clinical picture is...