Nervous System Neoplasms

Cinque casi, un unico messaggio: quando il neuroblastoma si presenta in modo atipico

Grassi C.

2026/26 — pag. 192-192 — DOI

Neuroblastoma is the most common extracranial solid tumour in children, yet its diagnosis is frequently delayed due to a highly heterogeneous clinical presentation at onset. While over 50% of cases originate in the adrenal medulla causing abdominal m...

Loretta dagli occhi tremanti

Barabino A.

2026/6 — pag. 360-361 — DOI

This narrative pediatrics piece recounts the clinical encounter with Loretta, an 8-year-old girl referred for daily early-morning vomiting associated with headache, mild weight loss, and easy fatigability. Initially framed as a possible functional or...

Cefalea e vomito, a pensar male spesso ci si azzecca

Zanin F

2025/9 — pag. 247-248 — DOI

An 11-year-old boy presenting with occipital headache and vomiting was diagnosed with a posterior fossa pilocytic astrocytoma. This case underscores the need to promptly identify red flag symptoms in paediatric headaches and to perform timely neuroim...

Una Kawasaki che mima una Guillain-Barré

Miotto D

2025/8 — pag. 220-221 — DOI

A 19-month-old boy presented with gait instability and lower limb weakness, initially suggestive of Guillain-Barré syndrome or transverse myelitis. Clinical features including fever, rash, conjunctivitis, sterile pyuria and elevated inflammation mark...

Rivista sfogliabile on line

2025/2

Sintomi atipici dei tumori del sistema nervoso centrale in età pediatrica

Pignataro F, Scisci E, Perillo T, Santoro N.

2025/2 — pag. 120-122 — DOI

Paediatric central nervous system (CNS) tumours are the second most common cancer in the 0 to 14 age group; additionally, they constitute the main cause of morbidity and death associated to cancer. Although intracranial hypertension-related and local...

Sintomi atipici dei tumori del sistema nervoso centrale in età pediatrica

Pignataro F, Scisci E, Perillo T, Santoro N

2025/2 — pag. 37-42 — DOI

Paediatric central nervous system (CNS) tumours are the second most common cancer in the 0 to 14 age group; additionally, they constitute the main cause of morbidity and death associated to cancer. Although intracranial hypertension-related and local...

Nistagmo e diplopia: occhio alla diagnosi

Savino V, Bellini T, Siri L, De Grandis E, Tortora D, Piccotti E.

2024/8 — pag. 532-534 — DOI

Medulloblastoma is the most common malignant brain tumour in children, primarily located in the cerebellum. This clinical case highlights the importance of maintaining a high clinical suspicion and conducting timely evaluations, even when symptoms ar...

Le manifestazioni parossistiche non epilettiche

Tratta E, Piacentini F, Pelosi P, Cupone R, Mirri S, Bini R, Mirri G, Ferrara G.

2024/8 — pag. 532-534 — DOI

A 9-month-old infant, under follow-up for neonatal sepsis due to Streptococcus agalactiae, presented to the Emergency Department with episodes of head drooping, sometimes accompanied by blinking. During the clinical examination, the infant showed nor...

Nistagmo e diplopia: occhio alla diagnosi

Savino V, Bellini T, Siri L, De Grandis E, Tortora D, Piccotti E

2024/8 — pag. 164-165 — DOI

Medulloblastoma is the most common malignant brain tumour in children, primarily located in the cerebellum. This clinical case highlights the importance of maintaining a high clinical suspicion and conducting timely evaluations, even when symptoms ar...

La sindrome diencefalica: magro, lungo e sorridente

Mercuri C, Piccolo G, Molteni M, Verrico A, Piatelli G, Gaggero G, Ramaglia A, Milanaccio C

2024/26 — pag. 1-1 — DOI

The Authors describe the case of a 10-month-old boy with growth arrest and nystagmus related to a pilomyxoid astrocytoma in a paramedian suprasellar location....

Vomito mattutino e cefalea: pensa male

Fenato A.

2024/6 — pag. 395-395 — DOI

The paper reports the case of a six-year-old child with progressively worsening headaches and morning vomiting over several months, initially attributed to an emotional disturbance. A pilocytic astrocytoma of the posterior cranial fossa was eventuall...

"Occhi che danzano, gambe che cedono": un caso di sindrome opsoclono-mioclono

Zucconi A, Matarese S

2024/1 — pag. 18-18 — DOI

The case of a 22-month-old girl presenting with opsoclonus, irritability and tremors of her upper limbs is presented. The diagnosis of thoracic neuroblastoma was finally made....

"È intelligente ma non si applica": quando è solo una questione di anticorpi

Carnazzo SM, Balconara D, Caruso F, Ruggieri M, Falsaperla R

2023/9 — pag. 194-197 — DOI

A diagnosis of steroid responsive encephalitis associated to autoimmune thyroiditis (Hashimoto encephalitis) was eventually made in a child with complex tics and decline of school performance....

Mal di testa? Non pensare all’oculista

Campone C, Negro I, Vandone M

2023/6 — pag. 104-104 — DOI

The paper describes the case of a 3-year-old girl presenting with worsening and severe headache initially attributed to astigmatism that was finally diagnosed as cerebellar pilocytic astrocytoma....

Le multiple facce della sclerosi multipla

de Martino L, Basilio P.

2023/4 — pag. 261-263 — DOI

The authors describe the case of a 14-year-old girl complaining a lack of strength at left hemisome and finally diagnosed with multiple sclerosis....

Esposizioni radiodiagnostiche in età evolutiva

Corbella D, Tinelli D, Righini A.

2022/3 — pag. 161-167 — DOI

An increase in the quantitative lifetime radiation risk in the paediatric age, correlated with an exponential rise in computed tomography (CT) examinations, has been observed worldwide. Moreover, a positive association between the exposure to radiati...

La psicosi e i disturbi psicotici nei bambini e negli adolescenti

Gamberini G, Secci I, Vitiello B.

2022/2 — pag. 103-113 — DOI

Psychosis can present a variety of symptoms such as hallucinations, delusions, catatonia, thought and speech disorganization, alogia, avolition and general functional decline. Transient psychotic symptoms are not uncommon during development and are n...

Quando non è un banale rigurgito

Lavagetto A, Mallamaci M

2021/7 — pag. 470-470 — DOI

The case of a one-month infant presenting with vomiting accompanied by cyanosis and fainting due to a congenital meningioangiomatosis is described. The clinical aspects and the pathogenesis of this rare condition are briefly discussed....

Il craniofaringioma

Salce N, Giovannelli E, Graziani V, Cozzolino M, Mazzatenta D, Zucchelli M, Marchetti F

2021/7 — pag. 467-469 — DOI

Craniopharyngioma (CP) is a rare epithelial low-grade tumour that develops in the sellar/suprasellar region of the brain, along the craniopharyngeal duct. It has a bimodal distribution and the first peak occurs in paediatric age almost exclusively co...

Donne e coltelli

Tonin G, Ganis R, Colonna F

2021/7 — pag. 465-466 — DOI

The authors discuss the case of a 31-month-old girl coming from Burkina Faso who presented with a severe genital mutilation....

Tra reflussi e torcicolli

Brocchi S, Mambelli L, Mainetti M, Cenni P, Romeo C, Zucchelli M, Marchetti F

2021/7 — pag. 464-465 — DOI

The paper descibes the cases of a 10-year-old girl and a 3-year-old boy with CNS neoplasia. The girl presented with acute vomiting and cervicalgia while in the boy vomiting persisted for three months as the only symptom and was iniatially misinterpre...

“Mi sembra tanto depresso”… aveva tutte le ragioni per esserlo!

Iacono A

2021/7 — pag. 463-466 — DOI

The paper reports - in the form of a dialogue between paediatricians - the case of an 8-year-old boy who presented with about 10 days of sporadic episodes of vomiting, profuse asthenia and change in behaviour. Brain MRI showed the presence of a crani...

Sclerosi tuberosa ed everolimus: una nuova storia

Cervesi C, Di Marzio GM, Kiren V, Cattaruzzi E, Costa P, Carrozzi M

2021/7 — pag. 443-449 — DOI

Tuberous sclerosis complex (TSC) is a rare autosomal dominant disorder, due to inactivating muta-tions of TSC1 or TSC2 mTOR pathway genes and is characterized by variable multisystem manifestations ranging from hamartomas to malignant neoplasms. It f...

Quando non è un banale rigurgito

Lavagetto A, Mallamaci M

2021/7 — pag. 217-217 — DOI

The case of a one-month infant presenting with vomiting accompanied by cyanosis and fainting due to a congenital meningioangiomatosis is described. The clinical aspects and the pathogenesis of this rare condition are briefly discussed....

Il craniofaringioma

Salce N, Giovannelli E, Graziani V, Cozzolino M, Mazzatenta D, Zucchelli M, Marchetti F

2021/7 — pag. 210-216 — DOI

Craniopharyngioma (CP) is a rare epithelial low-grade tumour that develops in the sellar/suprasellar region of the brain, along the craniopharyngeal duct. It has a bimodal distribution and the first peak occurs in paediatric age almost exclusively co...

Un bambino più lungo che largo

G. Trippella, C. Pizza, G. Palmas

2020/9 — pag. 237-237 — DOI

Una scoliosi rapidamente progressiva

B. Bossini

2020/26 — pag. 166-166 — DOI

Scuole chiuse? Sì, forse sì, più no che sì, no “Dalle Alpi alle piramidi…” scriveva il Poeta Antiemetici nella gastroenterite acuta Né farmaci... né radici di farfaraccio Neurofibromi plessiformi in NF1: conferme per selumetinib Cani e gatti... e fratelli

2020/5 — pag. 283-284

Occhi roteanti

M. Majorana

2019/8 — pag. 531-532

Uno stridore senza parole

P. Assandro

2019/7 — pag. 147-148

Amartoma ipotalamico e crisi gelastiche

M. Carrozzi, A. Skabar, C.E. Marras

2019/4 — pag. 258-260

Gelastic seizures (GS) are a rare form of epilepsy characterised by inappropriate, uncontrolled laughter. They usually originate from hypothalamic hamartomas. The paper presents a case of GS for which EEG and MR initially excluded the diagnosis made ...

Complicanze endocrinologiche nei bambini affetti da neurofibromatosi 1 e glioma delle vie ottiche

M. Scilipoti

2019/4 — pag. 93-93

Tick-borne encephalitis con associato quadro autoimmune? Due in una

R. Pillon

2019/4 — pag. 92-92

Amartoma ipotalamico e crisi gelastiche

M. Carrozzi, A. Skabar, C.E. Marras

2019/4 — pag. 83-85

Gelastic seizures (GS) are a rare form of epilepsy characterised by inappropriate, uncontrolled laughter. They usually originate from hypothalamic hamartomas. The paper presents a case of GS for which EEG and MR initially excluded the diagnosis made ...

L’adolescente obeso: è importante valutare i genitali

B. Mainetti, M.T. Nasi, E. Valletta

2018/9 — pag. 595-596

The article describes the case of an adolescent male with obesity and pubertal delay whose hormonal and imaging investigations led to the diagnosis of prolactin secreting pituitary adenoma. After cabergoline treatment, a decrease in prolactinoma size...

15 anni, amenorrea… pensa anche al prolattinoma!

A. Troisi, M. Cozzolino, G. Graziani, V. Graziani, M. Mainetti, P. Cenni, F. Marchetti

2018/9

Prolactinoma is a rare benign neoplasia in paediatric age that mostly affects female adolescents. In most cases the adopted therapy is pharmacological with dopamine-agonists and the first choice is cabergoline that shows a good safe and efficacious p...

L’adolescente obeso: è importante valutare i genitali

B. Mainetti, M.T. Nasi, E. Valletta

2018/9

The article describes the case of an adolescent male with obesity and pubertal delay whose hormonal and imaging investigations led to the diagnosis of prolactin secreting pituitary adenoma. After cabergoline treatment, a decrease in prolactinoma size...

Encefalite da Herpes virus in una lattante

A. Fumarola, P. Ricciardelli, S. Dal Bo, I. Moneta, V. Rizzo, M. Stella, P. Cenni, F. Marchetti

2018/8

The paper presents the case of an infant with HSV-1 herpetic encephalitis. The clinical symptomatology, after contact with the virus and the development of typical vesicular lesions, is characterized by involvement of the central nervous system, with...

Diplopia, strabismo a recente insorgenza e...

M. Ronconi

2018/4 — pag. 259-261

Le Giornate di Medico e Bambino. A Trieste Vaccinare sempre: dalla gravidanza in poi… Encefaliti mediate da autoanticorpi: un capitolo da conoscere bene Asma difficile: inutile alzare la dose di corticosteroidi inalatori Profilassi antibiotica per la cistouretrografia: SÌ! I bambini non vanno picchiati Kingella kingae: la più… bella del reame

2018/3 — pag. 147-148

Siparietto e allerta sulla sclerosi tuberosa PPI 2018 Opsoclono-mioclono-atassia Chi non ricorda di avere visto... Autolesionismo e abuso emotivo Anoressia. Cosa fare e come

2018/1 — pag. 9-10

Un dubbioso esordio di sclerosi multipla

P. Largo, F. Greco, E.C. Turco

2017/10

Sembrava un’ADEM e invece era un tumore cerebrale

A. Delise

2017/10

Le crisi gelastiche

C. Pierobon, D. Driul, G. Crichiutti

2016/3

Caduta dallo scivolo

M. Orrù

2015/10

Malformazioni linfatiche e venose complesse: prova il sirolimus Encefaliti: più autoimmuni che infettive Sesso prima della nascita ADHD e incidenti: un motivo in più per curare con il farmaco Bambini selettivi (nell’alimentazione) Kingella kingae: la regina delle artriti

2015/7 — pag. 421-422

Un caso particolare di pubertà precoce

P. Scalini, M. Giacalone, S. Ricci

2015/6

Atlante dermatologico pediatrico alfabetico di Medico e Bambino P

2014/11

Encefalite da anticorpi anti-NMDAR

T. Granata, S. Matricardi

2014/10 — pag. 637-641

Anti-N-metyl-D-aspartate receptor (NMDAR) antibodies encephalitis is a potentially treatable disease characterized by the abrupt onset of a constellation of symptoms resulting from diffuse brain dysfunction. First described in young women as parane...

Non cammina bene, ha “tremori” e gli occhi sembra che danzino...

M. Grassi, F. De Leonardis, P. Muggeo, M. Sesta, G. Paradies, N. Santoro

2014/7 — pag. 445-450

The paper reports the case of a 15-month-old girl who presented with abnormalities of gait, myoclonus and opsoclonus. Paediatric opsoclonus-myoclonus syndrome is associated in more than 50% to a neuroblastoma, generally with favorable prognosis. St...

Encefalite da anticorpi anti-NMDA-R: un caso atipico

G. Mastrangelo

2014/3

La neurofibromatosi di tipo 2

2013/10 — pag. 660-661

La solita cefalea?

E. Alberti, M. Del Pistoia, M. Leoni, F. Vierucci

2013/2

Troppa acqua non fa crescere

S. Naviglio, M.C. Pellegrin, G. Patti

2012/7

Questione di... tuberi

L. Matarazzo

2012/7

Non tutti i mali vengono per nuocere

N. Gaias, D. Bettati

2012/7

Piccolo Proust

A. Skabar

2012/6 — pag. 397-398

Quando si dice...ha una testa un po’ grande...!

S. Bertelli, I. Cogo, C. Radice, R. Faggioli

2012/6

Para-paresi: un raro esordio di linfoma di Hodgkin

L. Baroni, S. Fornaciari, E. Bigi, M. Codifava, P. Bergonzini, A. Guerra, L. Iughetti, P. Paolucci

2012/5

Una mielite di origine incerta

G. Barbato, G. Monti, L. Leoni, M. Marchesi, E. Pavlidis, G. Cantalupo, F. Pisani, N. Carano

2011/6 — pag. 397-398

Transverse myelitis is a neurologic syndrome caused by acute or subacute inflammation of the spinal cord. Since its incidence is about 0.5/100,000 children/year, transverse mielitis is included in the group of rare diseases. The pathogenesis of the d...

Cellulari e tumori cerebrali: evidenze limitate, precauzioni doverose

G. Tamburlini

2011/6 — pag. 347-349

Una mielite di origine incerta

G. Barbato, G. Monti, L. Leoni, M. Marchesi, E. Pavlis, G. Cantalupo, F. Pisani, N. Carano

2011/6

Transverse myelitis is a neurologic syndrome caused by acute or subacute inflammation of the spinal cord. Since its incidence is about 0.5/100,000 children/year, transverse mielitis is included in the group of rare diseases. The pathogenesis of the d...

Un reflusso gastroesofageo molto maligno

M. Grassi, V. Cecinati, F. De Leonardis, D. Amato, L.P. Brescia, D. De Mattia, N. Santoro

2010/8 — pag. 529-530

We report a case of a 13-year-old boy with recurrent episodes of vomiting. Initially a diagnosis of gastroesophageal reflux with esophagitis was made. The patient also showed bradycardia and deflections of mood. Neurological assessment and examin...

Un reflusso gastroesofageo molto maligno

M. Grassi, V. Cecinati, F. De Leonardis, D. Amato, L.P. Brescia, D. De Mattia, N. Santoro

2010/8

We report a case of a 13-year-old boy with recurrent episodes of vomiting. Initially a diagnosis of gastroesophageal reflux with reflux esophagitis was made. The patient also showed bradycardia and deflections of mood. Neurological assessment and...

Una curva di troppo: astrocitoma pilocitico

G. Guerrini, E. Fabbri, C. Malaventura, R. Burnelli

2010/8

Neurofibromatosi tipo I (parte seconda)

G. Bartolozzi

2009/3

Neurofibromatosi tipo I (parte prima)

G. Bartolozzi

2009/2

Immagini da fissare nella mente: tra Casi Indimenticabili e Confronti in PediatriaCeliachia, sepsi e altre considerazioniAsma moderato-persistente: un’altra vittoria della terapia “a scelta del paziente”Tumori cerebrali nel primo anno divitaEBM e test rapido di infezione pneumococcicaPrevenzione dell’infarto “per legge”

2008/7 — pag. 419-420

Ipertrofia clitoridea in bambina affetta da neurofibromatosi di tipo 1

E. Ballerini, R. Luksch

2006/9 — pag. 601-602

We report the case of NF1 in a 21 month old female, who presented with hypertrophy of the clitoris. The work-up evaluations revealed the presence of multiple pelvic and abdominal neurofibromas and concomitant histologically assessed presacral ganglio...

Ipertrofia clitoridea in bambina affetta da neurofibromatosi di tipo 1

E. Ballerini, R. Luksch

2006/9

Rigidità nucale e mioclonie ipniche all’arto superiore destro come sintomi di esordio di astrocitoma midollare

2003/1 — pag. 58-58

Case description of a spinal astrocytoma with very slow onset and very discrete initial signs (stiff neck, partial paresis of two fingers of the right hand). The child was admitted to hospital for the presence of localized sleep myoclonias of the ...

La storia di martina: un mal di testa ingravescente

S. Castelli

2002/8 — pag. 530-531

Malattie maligne e Pediatria di Famiglia

M&B

2002/8 — pag. 483

Una paralisi completa degli arti in una bambina di 10 anniUn caso clinico dalla letteratura internazionale

G. Bartolozzi

2001/9

Gli enterovirus e virus coxsackie come causa di paralisi flaccida, polio-simileUso dei telefoni cellulari e tumori del cervelloUn gatto in casa riduce il rischio di asmaPermetrina + cotrimossazolo: nuova cura per i pidocchi?Vaccinazione con BCG ed equilibrio Th1/Th2Infezioni da Mycoplasma pneumoniae e risposte Th2Colite ulcerosa e appendicectomiaEfficacia del vaccino contro la varicellaIl sottotipo "adw" del virus dell'epatite B aumenta di 20 volte la lamivudina-resistenzaI ceppi europei di pneumococco sono gli stessi di quelli presenti in USA ? ovvero il vaccino USA va bene per l'Europa ?

G. Bartolozzi

2001/4

Distonia parossistica oculare (encefalite da CMV?)

A. D’Apuzzo, R. De Nicola, V. Rosanova, F. De Rosa, G. Amendola, M. Spiezie, L. Amato

2000/8

Uno strabismo autoimmune molto istruttivo

P.A. Battistella

2000/7 — pag. 460-462

Cisti aracnoidea associata a nevo di Becker

C. De Meco, M. Crisetti, M. Germano, Mi. Jussi, P. Paolucci

1999/8

Cisti aracnoidea associata a nevo di becker

C. De Meco, M. Crisetti, M. Germano, M.I. Jussi, P. Paolucci

1999/8 — pag. 471-472

Il trapianto di midollo: un passo avanti per le malattie autoimmuni intrattabili

M. Andolina e coll.

1998/4 — pag. 233-236

We report the results of a series of autologous stem cell transplants in autoimmune diseases. The stem cells were treated ex vivo with vincristine and methylprednisolone as previously in allogeneic mismatched transplants in advanced leukemia. T...